ALOX15 (also termed arachidonate 15-lipoxygenase, 15-lipoxygenase-1, 15-LO-1, 15-LOX-1) is, like other lipoxygenases, a seminal enzyme in the metabolism...

unusual in that lymphocytes typically express little or no ALOX15. It is suggested that ALOX15 and/or ALOX15B, perhaps operating through one of its arachidonic...

of 662–711 amino acids. Mammalian LOX genes contain 14 (ALOX5, ALOX12, ALOX15, ALOX15B) or 15 (ALOX12B, ALOXE3) exons with exon/intron boundaries at highly...

similar fashions, 15-lipoxygenase (15-lipoxygenase 1, 15-LOX, 15-LOX1, or ALOX15) initiates the metabolism of arachidonic acid to 15-HpETE, 15-HETE, eoxins...

(also see 5-Hydroxyeicosatetraenoic acid). The enzymes 15-lipoxygenase-1 (ALOX15) and 15-lipoxygenase-2 (ALOX15B). ALOX15B catalyzes the oxidation of arachidonic...

11Z,14Z-eicosatetraenoic acid) with a) ALOX15 (or possibly ALOX15B) followed by ALOX5; b) ALOX5 followed by ALOX15 (or possibly ALOX15B); or c) ALOX5 followed...

15-lipoxygenase-2 (15-LO-2 or 15-LOX-2), is distinguished from its related oxygenase, ALOX15 or 15-lipoxygenase-1. This gene encodes a member of the lipoxygenase family...

deemed an ortholog of ALOX15 and is designated as Alox15. Human ALOX12 and ALOX15 along with rodent leukocyte-type Alox12 and Alox15 are commonly termed...

HGNC:436 P20292 592 ALOX12 HGNC:429 P18054 593 ALOX12B HGNC:430 O75342 594 ALOX15 HGNC:433 P16050 595 ALOX15B HGNC:434 O15296 596 ALOXE3 HGNC:13743 Q9BYJ1...

responsible for metabolizing PUFA to resolvins: 15-lipoxygenase-1 (i.e. ALOX15), possibly 15-lipoxygenase-2 (i.e. ALOX15B), 5-lipoxygenase (i.e. ALOX5)...

the maresins, this class of mediators includes: the 15-lipoxygenase (i.e. ALOX15 and/or possibly ALOX15B)-derived lipoxin A4 and B4 metabolites of the omega...

15-oxo-eicosatetraenoic acid is an eicosanoid metabolite of arachidonic acid made my ALOX15; it has weak chemotactic activity for human monocytes (sees 15-Hydroxyeicosatetraenoic...

leukotriene and 5-hydroxyicosatetraenoic acid metabolites and 15-lipoxygenase (ALOX15) to overproduce pro-inflammatory 15-hydroxyicosatetraenoic acid metabolites...

catalyzed by enzymes with 15-lipoxygenase activity which in humans includes ALOX15, ALOX12, aspirin-treated cyclooxygenase 2, and cytochrome P450s of the microsomal...

distinction to the other three human lipoxygenases (ALOX5, ALOX12, and ALOX15), because they were initially defined as being highly or even exclusively...

987, 7 March 2018 RP Kristjansson et al., "A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis," Nature Genetics...

globin (HBA1 or HBA2, NM_000517.1) cccca-----cccu—cuuccccaa lipoxygenase (ALOX15, NM_001140) -ccca----gcccacuuuuccccaa alpha(I)-collagen (COL1A1, NM_000088)...

composed of two β-sheets of four β-strands each. ALOX12; ALOX12B; ALOX12P2; ALOX15; ALOX15B; ALOX5; ALOXE3; LIPC; LIPG; LOXHD1; LPL; PKD1; PKD1L1; PKD1L2;...

another pathway, ALOX5 may act in series with a second lipoxygenase enzyme, ALOX15, to metabolize AA to lipoxin A4 (LxA4) and LxB4 (see Specialized pro-resolving...

activity may be responsible for blocking the formation of the hepoxilins. ALOX15 is responsible for metabolizing arachidonic acid to 14,15-HxA3 and 14,15-HxB3...

metabolism is proposed to represent a pathway for 5(S)-HETE inactivation. ALOX15 to metabolize 5(S)-HETE to 5(S),15(S)-dihydroxy-eicosatetraenoate (5,15-diHETE)...

implicated in working together to signal for pain perception. 15-lipoxygenase 1 (ALOX15), while best known for converting the 20 carbon polyunsaturated fatty acid...

(12(S)-HpETE or 12S-HpETE). Arachidonate 15-lipoxygenase-1 (15-LO-1, 15-LOX-1, ALOX15), which is expressed in far more tissues that ALOX12, metabolizes arachidonic...

regulation of the animals’ ability to survive in low-oxygen environments (ALOX15). In the Yosemite transect, no significant change in avian species abundance...

15(S)-HpETE): Eoxin A4 Eoxin C4 Eoxin D4 Eoxin E4 A 15-lipoxygenase (i.e. ALOX15 or ALOX15B) metabolizes arachidonic acid to 15(S)-HpETE (see 15-Hydroxyicosatetraenoic...

Cells metabolize arachidonic acid with 15-lipoxygenase-1 (i.e., 15-LO-1, ALOX15) to form 15(S)-HpETE as a major product and 12(S)-hydroperoxy-5Z,8Z,10E...

in treating these skin, lung, and, possibly, nasal reactions in humans. ALOX15 5-Hydroxyeicosanoid dehydrogenase 5-HETE OXER1 Powell WS, Rokach J (April...

15S-diHETE probably by double oxygenation of AA by a 15-lipoxygenase (probably ALOX15) or serial metabolism by two enzymes. Linotrin-1 and linotrin-2 are among...

reduced to 9(S)-HODE. However, ALOX15B, similar to human 15-lipoxygenase-1 (ALOX15), metabolizes linoleic acid to 13(S)-HODE but not to 9(S)-HODEs. Like most...