• Thumbnail for Apoptosis
    Apoptosis (from Ancient Greek: ἀπόπτωσις, romanized: apóptōsis, lit. 'falling off') is a form of programmed cell death that occurs in multicellular organisms...
    91 KB (10,639 words) - 20:17, 21 November 2024
  • play an integral role in apoptosis. Some of these inhibitors include the Bcl-2 family, viral inhibitor crmA, and IAP's. Apoptosis, or programmed cell death...
    13 KB (1,572 words) - 12:11, 13 September 2024
  • REVIEW: Apoptosis - Allegaeon". Distorted Sound. Retrieved April 23, 2019. Gill, Kim (April 17, 2019). "ALBUM REVIEW: Allegaeon - Apoptosis". Ghost Cult...
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  • mitochondrial pathway to apoptosis and illuminated whole new avenues of research on inflammatory diseases, cancer, and apoptosis in general. By 1998, research...
    12 KB (1,598 words) - 09:38, 22 June 2024
  • Thumbnail for Fas ligand
    other hallmarks of apoptosis. Some reports have suggested that the extrinsic Fas pathway is sufficient to induce complete apoptosis in certain cell types...
    22 KB (2,547 words) - 08:19, 11 August 2024
  • Thumbnail for Phosphatidylserine
    Phosphatidylserine plays a crucial role in the process of apoptosis, or programmed cell death. During apoptosis, PS translocates from the inner to the outer leaflet...
    21 KB (1,971 words) - 08:50, 14 October 2024
  • Thumbnail for Bcl-2 family
    proteins consists of members that either promote or inhibit apoptosis, and control apoptosis by governing mitochondrial outer membrane permeabilization...
    16 KB (2,141 words) - 20:27, 19 November 2024
  • Thumbnail for Apoptosis-inducing factor
    Apoptosis inducing factor is involved in initiating a caspase-independent pathway of apoptosis (positive intrinsic regulator of apoptosis) by causing...
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  • Thumbnail for Cell death
    of "apoptosis" such as endonuclease activation can be spuriously induced without engaging a genetic cascade, however, presumably true apoptosis and programmed...
    16 KB (1,909 words) - 19:13, 26 September 2024
  • Thumbnail for Necrosis
    components. In contrast, apoptosis is a naturally occurring programmed and targeted cause of cellular death. While apoptosis often provides beneficial...
    29 KB (3,252 words) - 06:36, 4 November 2024
  • Apoptosis inhibitor of macrophage (AIM) is a protein produced by macrophages that regulates immune responses and inflammation. It plays a crucial role...
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  • Thumbnail for PAWR
    PRKC apoptosis WT1 regulator protein, or Prostate apoptosis response-4, is a tumor-suppressor protein coded for in the human by the PAWR gene, that induces...
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  • Thumbnail for CFLAR
    CASP8 and FADD-like apoptosis regulator is a protein that in humans is encoded by the CFLAR gene. Also called c-FLIP (FLICE-like inhibitory protein)....
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  • Thumbnail for Cytochrome c
    protect themselves from apoptosis by blocking the release of cytochrome c using Bcl-xL. Another way that cells can control apoptosis is by phosphorylation...
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  • connections undergo apoptosis. Programmed cell death is also necessary to start the process of menstruation. That's not to say that apoptosis is a perfect process...
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  • Programmed cell death (category Apoptosis)
    hypothesized that necroptosis can serve as a cell-death backup to apoptosis when the apoptosis signaling is blocked by endogenous or exogenous factors such...
    55 KB (6,748 words) - 20:29, 10 November 2024
  • Thumbnail for Inhibitor of apoptosis domain
    The inhibitor of apoptosis domain -- also known as IAP repeat, Baculovirus Inhibitor of apoptosis protein Repeat, or BIR -- is a structural motif found...
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  • estimated that 50 to 70 billion cells die each day from apoptosis. One of the largest promoters of apoptosis is exposure to ultraviolet (UV) light. While UV light...
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  • Thumbnail for P53 upregulated modulator of apoptosis
    with it induces apoptosis. Various studies have shown though, that PUMA does not rely on direct interaction with Bax/Bak to induce apoptosis. The majority...
    28 KB (3,387 words) - 06:12, 27 December 2023
  • Thumbnail for TRAIL
    TNF-related apoptosis-inducing ligand (TRAIL), is a protein functioning as a ligand that induces the process of cell death called apoptosis. TRAIL is a...
    11 KB (1,335 words) - 12:37, 19 July 2024
  • Thumbnail for Death mask
    Temporal lobe necrosis Programmed cell death AICD Anoikis Apoptosis Autophagy Intrinsic apoptosis Necroptosis Paraptosis Parthanatos Phenoptosis Pseudoapoptosis...
    13 KB (1,360 words) - 14:29, 27 October 2024
  • Thumbnail for Reactive oxygen species
    (CDC25). A cancer cell can die in three ways: apoptosis, necrosis, and autophagy. Excessive ROS can induce apoptosis through both the extrinsic and intrinsic...
    70 KB (8,492 words) - 09:37, 20 November 2024
  • Thumbnail for Viral shedding
    forcing the cell to undergo apoptosis or cell suicide, release of progeny into the extracellular space is possible. However, apoptosis does not necessarily result...
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  • Thumbnail for Apoptosis regulator BAX
    Apoptosis Apoptosome Bcl-2 BH3 interacting domain death agonist (BID) Caspases Cytochrome c Noxa Mitochondrion p53 upregulated modulator of apoptosis...
    18 KB (2,092 words) - 06:47, 29 September 2024
  • Thumbnail for Fas receptor
    that leads to programmed cell death (apoptosis) if it binds its ligand, Fas ligand (FasL). It is one of two apoptosis pathways, the other being the mitochondrial...
    23 KB (2,675 words) - 19:25, 12 November 2023
  • Thumbnail for Philadelphia chromosome
    to DNA damage and promotes apoptosis in normal cells. The BCR-ABL fusion, in contrast, has been shown to inhibit apoptosis, but its effect on DNA binding...
    29 KB (3,538 words) - 15:01, 5 December 2023
  • Thumbnail for The Hallmarks of Cancer
    occur, thus apoptosis cannot activate. They may also have defects in the downstream signaling itself, or the proteins involved in apoptosis, each of which...
    24 KB (2,745 words) - 20:25, 21 November 2024
  • enzyme has an adverse effect on the tumor suppressor, p53. p53 is an apoptosis transcription factor normally found in the cytosol. When cellular DNA...
    42 KB (4,944 words) - 11:56, 4 April 2024
  • Thumbnail for Karyorrhexis
    as a result of either programmed cell death (apoptosis), cellular senescence, or necrosis. In apoptosis, the cleavage of DNA is done by Ca2+ and Mg2+...
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  • Thumbnail for Apoptosis-inducing factor, mitochondria-associated 3
    Smoot DT (2008). "H. pylori-induced apoptosis in human gastric cancer cells mediated via the release of apoptosis-inducing factor from mitochondria"....
    3 KB (356 words) - 11:36, 4 March 2023