Galactosidase alpha is an enzyme that in humans is encoded by the GLA gene. Two recombinant forms of human α-galactosidase are called agalsidase α (INN)...

functions.[citation needed] At least 443 disease-causing mutations in the GLA gene have been discovered. The DNA mutations that cause the disease are X-linked...

glycoproteins, glycolipids, and polysaccharides. The enzyme is encoded by the GLA gene. This enzyme is a homodimeric glycoprotein that hydrolyses the terminal...

Alpha-galactosidase, a glycoside hydrolase enzyme GLA (gene), an encoding of the enzyme alpha-galactosidase A Gla domain, a protein domain Gamma-Linolenic acid...

Matrix Gla protein (MGP) is member of a family of vitamin K2 dependent, Gla-containing proteins. MGP has a high affinity binding to calcium ions, similar...

carboxylation to form γ-carboxyglutamate (Gla). Proteins with this domain are known informally as Gla proteins. The Gla residues are responsible for the high-affinity...

Joe are all killed (the last of these murdered by Gene Lorrene, who sought revenge against the GLA). Mr. Immortal is also killed several times, though...

The bone Gla protein osteocalcin, the calcification-inhibiting matrix Gla protein (MGP), the cell growth regulating growth arrest specific gene 6 protein...

integrins to support adhesion and migration of epithelial cells. Periostin is a gla domain vitamin K dependent factor. Periostin is a secreted extracellular...

"Contributions of Gla and EGF-like domains to the function of vitamin K-dependent coagulation factors". Critical Reviews in Eukaryotic Gene Expression. 9...

terminus of the molecule to gamma-carboxyglutamic acid (Gla). In the presence of calcium, the Gla residues promote the binding of prothrombin to phospholipid...

Because osteocalcin has gla domains, its synthesis is vitamin K dependent. In humans, osteocalcin is encoded by the BGLAP gene. Its receptors include GPRC6A...

γ-carboxyglutamate residues are present in the γ-carboxyglutamic acid-rich ("GLA") domain. This GLA domain is known to be found in over a dozen known proteins, including...

that produces Factor VLeiden was noted (Bertina et al.). Two years later, Gla-domainless APC was imaged at a resolution of 2.8 Ångströms. Beginning with...

architecture. The factor IX protein is composed of four protein domains: the Gla domain, two tandem copies of the EGF domain and a C-terminal trypsin-like...

an N-terminal gamma-carboxyglutamic acid (Gla) containing module (the Gla module). In vitro studies on the Gla-cbEGF tandem isolated from factor X revealed...

resident protein 60 (ERp60) is a protein that in humans is encoded by the CALR gene. Calreticulin is a multifunctional soluble protein that binds Ca2+ ions (a...

signaling. In humans, the calretinin protein is encoded by the CALB2 gene. This gene encodes an intracellular calcium-binding protein belonging to the troponin...

in the signaling function of TF. Note that one of factor VIIa's domains, GLA domain, binds in the presence of calcium to negatively charged phospholipids...

so the function of the encoded enzyme is essential for hemostasis. Most gla domain-containing proteins depend on this carboxylation reaction for posttranslational...

brains of patients with schizophrenia. Transthyretin is known to contain a Gla domain, and thus be dependent for production on post-translational modification...

catalyzes γ‐carboxylation of specific glutamic acid residues in Gla‐factors/proteins (Gla domain) leading to their activation and participation in blood...

and flax oil). Another example is DGLA (20:3 ω-6), derived from dietary GLA (18:3 ω-6), is found in borage oil and can also. These two parallel cascades...

It was originally found as a gene upregulated by growth arrested fibroblasts. Gas6 is a gamma-carboxyglutamic acid (Gla) domain-containing protein thought...

large and 396 amino acids long. The PROZ gene is located on chromosome 13 (13q34). It has four domains: a GLA-rich region, two EGF-like domains and a trypsin-like...

JC, Adler DA, Disteche CM (1992). "Chromosomal localization of the human gene for annexin V (placental anticoagulant protein I) to 4q26----q28". Cytogenetics...

and neuronal), controlling nitric oxide production. Proline rich Gla, PRRG2, has a Gla domain which binds hyaluronan and is associated with proteins present...

Rickettsia resistance (Ric), is a protein that in humans is encoded by the SPP1 gene (secreted phosphoprotein 1). The murine ortholog is Spp1. Osteopontin is...

chain H2 is a protein that in humans is encoded by the ITIH2 gene. It is known to contain a Gla domain, and thus be dependent for production on post translational...

PLN or PLB, is a micropeptide protein that in humans is encoded by the PLN gene. Phospholamban is a 52-amino acid integral membrane protein that regulates...