• Gi protein alpha subunit is a family of heterotrimeric G protein alpha subunits. This family is also commonly called the Gi/o (Gi /Go ) family or Gi/o/z/t...
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  • Alpha subunits (α) refers to several protein subunits, e.g.: G proteins Gi alpha subunit Gs alpha subunit Gq alpha subunit The pore-forming loop of ion...
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  • Gq protein alpha subunit is a family of heterotrimeric G protein alpha subunits. This family is also commonly called the Gq/11 (Gq/G11) family or Gq/11/14/15...
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  • Thumbnail for Gs alpha subunit
    The Gs alpha subunit (Gαs, Gsα) is a subunit of the heterotrimeric G protein Gs that stimulates the cAMP-dependent pathway by activating adenylyl cyclase...
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  • membership network GI, a complexity class in the graph isomorphism problem Galvanized iron Gi alpha subunit, a protein Gastrointestinal tract (GI tract) Gigantocellular...
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  • Thumbnail for GNAI3
    with: RGS10 RGS12, RGS14, RGS16, RGS18, RGS19, RGS5, RIC8A, and S1PR1. Gi alpha subunit GRCh38: Ensembl release 89: ENSG00000065135 – Ensembl, May 2017 GRCm38:...
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  • Thumbnail for GNAI1
    J, Spiegel A, Nirenberg M (Aug 1987). "Human cDNA clones for an alpha subunit of Gi signal-transduction protein". Proceedings of the National Academy...
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  • Thumbnail for G protein
    class of complexes is made up of alpha (Gα), beta (Gβ) and gamma (Gγ) subunits. In addition, the beta and gamma subunits can form a stable dimeric complex...
    24 KB (2,754 words) - 20:56, 30 July 2024
  • protein-coupled receptor Heterotrimeric G protein Gs alpha subunit Gi alpha subunit Gq alpha subunit Rho family of GTPases Dhanasekaran N, Dermott JM (1996)...
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  • Thumbnail for Μ-opioid receptor
    It is an inhibitory G-protein coupled receptor that activates the Gi alpha subunit, inhibiting adenylate cyclase activity, lowering cAMP levels. The structure...
    49 KB (4,883 words) - 09:13, 25 September 2024
  • Thumbnail for Heterotrimeric G protein
    the G-protein by exchanging the GDP on the alpha subunit to GTP. The binding of GTP to the alpha subunit results in a structural change and its dissociation...
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  • and activate, i.e. those containing the Gs alpha subunit, Gi alpha subunit, Gq alpha subunit and/or G12 subunit; and f) signaling pathways which they regulate...
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  • Thumbnail for G alpha subunit
    G alpha subunits are one of the three types of subunit of guanine nucleotide binding proteins, which are membrane-associated, heterotrimeric G proteins...
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  • Thumbnail for Metabotropic glutamate receptor 2
    mGluR2 is a G protein-coupled receptor (GPCR) that couples with the Gi alpha subunit. The receptor functions as an autoreceptor for glutamate, that upon...
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  • Thumbnail for G protein-gated ion channel
    Furthermore, studies have shown that G proteins, specifically the Gi alpha subunit, directly activate GIRKs which were found to participate in propagation...
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  • Thumbnail for Cav1.2
    voltage-dependent, L type, alpha 1C subunit (also known as Cav1.2) is a protein that in humans is encoded by the CACNA1C gene. Cav1.2 is a subunit of L-type voltage-dependent...
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  • Thumbnail for Alpha-2A adrenergic receptor
    relative interactions between the alpha 2C10 adrenoceptor and the guanine-nucleotide-binding proteins G(o)1 alpha and Gi 2 alpha following co-expression of these...
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  • an attached intracellular heterotrimeric G protein complex. The Gs alpha subunit of the stimulated G protein complex exchanges GDP for GTP and is released...
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  • Thumbnail for Prostaglandin DP2 receptor
    triggers Gi alpha subunit-linked heterotrimeric G proteins to dissociate into their component a) Gi alpha subunits (also termed Giα subunits) inhibit...
    26 KB (3,216 words) - 05:46, 16 September 2024
  • Thumbnail for Alpha-2 adrenergic receptor
    The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein. It consists...
    25 KB (2,231 words) - 17:54, 18 September 2024
  • Thumbnail for 5-Oxo-eicosatetraenoic acid
    site which reversibly bound 5-oxo-ETE and had the attributes of a Gi alpha subunit-linked G protein-coupled receptor based on the ability of 5-oxo-ETE...
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  • Thumbnail for Regulator of G protein signaling
    "GAIP and RGS4 are GTPase-activating proteins for the Gi subfamily of G protein alpha subunits". Cell. 86 (3): 445–52. doi:10.1016/S0092-8674(00)80117-8...
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  • Thumbnail for Luteinizing hormone
    glycoprotein. Each monomeric unit is a glycoprotein molecule; one alpha and one beta subunit make the full, functional protein. Its structure is similar to...
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  • Thumbnail for 5-Hydroxyeicosatetraenoic acid
    receptor). OXER1 couples to the G protein complex composed of the Gi alpha subunit (Gαi) and G beta-gamma complex (Gβγ); when bound to a 5-(S)-HETE family...
    48 KB (6,107 words) - 06:42, 13 August 2024
  • Thumbnail for GNAI2
    of Medicine. Didsbury JR, Ho YS, Snyderman R (Jan 1987). "Human Gi protein alpha-subunit: deduction of amino acid structure from a cloned cDNA". FEBS Letters...
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  • In contrast, the binding of PDG2 to PTGDR2 instead activates the Gi alpha subunit, decreasing cAMP levels and increasing intracellular calcium ion levels...
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  • Thumbnail for Alpha blocker
    Alpha-blockers, also known as α-blockers or α-adrenoreceptor antagonists, are a class of pharmacological agents that act as antagonists on α-adrenergic...
    34 KB (3,215 words) - 03:11, 10 September 2024
  • Thumbnail for 12-Hydroxyheptadecatrienoic acid
    ligand-bound, activate cells by releasing the Gq alpha subunit and pertussis toxin-sensitive Gi alpha subunit from Heterotrimeric G proteins. BLT1 receptor...
    32 KB (3,734 words) - 09:00, 24 January 2024
  • Thumbnail for Muscarinic acetylcholine receptor
    bioinformatic techniques. G proteins contain an alpha-subunit that is critical to the functioning of receptors. These subunits can take a number of forms. There are...
    31 KB (2,714 words) - 18:27, 22 September 2024
  • Thumbnail for Luteinizing hormone beta polypeptide
    Luteinizing hormone subunit beta also known as lutropin subunit beta or LHβ is a polypeptide that in association with an alpha subunit common to all gonadotropin...
    9 KB (1,112 words) - 00:24, 8 November 2023