Hydroxycarboxylic acid receptor 2 (HCA2), also known as GPR109A and niacin receptor 1 (NIACR1), is a protein which in humans is encoded (its formation...
50 KB (6,317 words) - 17:37, 30 March 2024
The hydroxycarboxylic acid receptor (abbreviated HCA receptor and HCAR) family includes the following human proteins: Hydroxycarboxylic acid receptor 1...
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D-β-hydroxybutyric acid is one of two primary endogenous agonists of hydroxycarboxylic acid receptor 2 (HCA2), a Gi/o-coupled G protein-coupled receptor (GPCR)....
14 KB (1,416 words) - 10:31, 24 August 2024
Hydroxycarboxylic acid receptor 3 (HCA3), also known as niacin receptor 2 (NIACR2) and GPR109B, is a protein which in humans is encoded by the HCAR3 gene...
7 KB (756 words) - 02:18, 10 March 2024
Hydroxycarboxylic acid receptor 1 (HCA1), formerly known as G protein-coupled receptor 81 (GPR81), is a protein that in humans is encoded by the HCAR1...
6 KB (768 words) - 07:04, 23 December 2023
Alpha hydroxy acid Beta hydroxy acid Omega hydroxy acid Hydroxycarboxylic acid receptor Miltenberger, Karlheinz (2000). "Hydroxycarboxylic Acids, Aliphatic"...
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butyric acid is one of two primary endogenous agonists of human hydroxycarboxylic acid receptor 2 (HCA2), a Gi/o-coupled G protein-coupled receptor. Butyric...
65 KB (6,428 words) - 03:51, 25 June 2024
tetrahydrocannabinol. The receptor was identified among cDNAs based on its similarity in amino-acid sequence to the cannabinoid receptor 1 (CB1) receptor, discovered...
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(also known as hydroxycarboxylic acid receptor 3, HCA3, niacin receptor 2, and NIACR2) binds and is activated by the medium-chain fatty acid, 3-hydroxyoctanoate...
26 KB (2,804 words) - 02:55, 24 May 2024
L-lactic acid is the primary endogenous agonist of hydroxycarboxylic acid receptor 1 (HCA1), which is a Gi/o-coupled G protein-coupled receptor (GPCR)....
39 KB (4,182 words) - 11:21, 15 August 2024
involve FFAR2, e.g., they activate FFAR3, GPR109A (now termed hydroxycarboxylic acid receptor 2 or HCA2), and two other GPRs, Olfr78 and Olfr558. Most of...
70 KB (8,749 words) - 19:14, 27 March 2024
receptor 1 (HCAR1, GPR81) Hydroxycarboxylic acid receptor 2, Niacin receptor 1 (HCAR2, GPR109A) Hydroxycarboxylic acid receptor 3, Niacin receptor 2 (HCAR3...
25 KB (2,172 words) - 01:01, 29 November 2023
Niacin (redirect from Nicotinic Acid)
activation of G protein-coupled receptors, including hydroxycarboxylic acid receptor 2 (HCA2)and hydroxycarboxylic acid receptor 3 (HCA3), which are highly...
92 KB (8,789 words) - 16:52, 1 July 2024
are activated by certain fatty acids that are 6 to more than 21 carbon atoms long. Hydroxycarboxylic acid receptor 2 is also activated by a SC-FA that...
48 KB (6,095 words) - 16:42, 29 June 2024
express one of the SC-FA receptors, i.e., free fatty acid receptor 2, free fatty acid receptor 3, or hydroxycarboxylic acid receptor 2. (For the functions...
53 KB (6,957 words) - 15:30, 8 July 2024
Vasopressin receptor 2 (V2R), or arginine vasopressin receptor 2 (officially called AVPR2), is a protein that acts as receptor for vasopressin. AVPR2 belongs...
15 KB (1,740 words) - 11:59, 4 January 2024
Dopamine receptor D2, also known as D2R, is a protein that, in humans, is encoded by the DRD2 gene. After work from Paul Greengard's lab had suggested...
34 KB (3,959 words) - 11:00, 25 July 2024
TAS1R1+TAS1R3 heterodimer receptor functions as an umami receptor, responding to L-amino acid binding, especially L-glutamate. The umami taste is most...
42 KB (4,345 words) - 16:41, 19 June 2024
(α1) adrenergic receptors are G protein-coupled receptors (GPCRs) associated with the Gq heterotrimeric G protein. α1-adrenergic receptors are subdivided...
16 KB (1,528 words) - 10:28, 23 June 2024
Lysophosphatidic acid receptor 2 (LPAR2; formerly known as EDG4) Lysophosphatidic acid receptor 3 (LPAR3; formerly known as EDG7) Lysophosphatidic acid receptor 4 (LPAR4;...
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The adrenergic receptors or adrenoceptors are a class of G protein-coupled receptors that are targets of many catecholamines like norepinephrine (noradrenaline)...
33 KB (2,982 words) - 11:42, 7 August 2024
The alpha-2 (α2) adrenergic receptor (or adrenoceptor) is a G protein-coupled receptor (GPCR) associated with the Gi heterotrimeric G-protein. It consists...
25 KB (2,231 words) - 08:33, 22 August 2024
glutamate receptors, such as NMDA (N-methyl-D-aspartate), AMPA (α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), and kainate receptors, have distinct...
63 KB (6,876 words) - 18:10, 26 April 2024
Opioid receptors are a group of inhibitory G protein-coupled receptors with opioids as ligands. The endogenous opioids are dynorphins, enkephalins, endorphins...
40 KB (4,427 words) - 12:37, 12 January 2024
GABAB receptors (GABABR) are G-protein coupled receptors for gamma-aminobutyric acid (GABA), therefore making them metabotropic receptors, that are linked...
16 KB (1,564 words) - 20:19, 25 March 2024
The GABA receptors are a class of receptors that respond to the neurotransmitter gamma-aminobutyric acid (GABA), the chief inhibitory compound in the...
35 KB (3,892 words) - 05:20, 16 May 2024
The angiotensin II receptors, (ATR1) and (ATR2), are a class of G protein-coupled receptors with angiotensin II as their ligands. They are important in...
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The beta-2 adrenergic receptor (β2 adrenoreceptor), also known as ADRB2, is a cell membrane-spanning beta-adrenergic receptor that binds epinephrine (adrenaline)...
33 KB (3,380 words) - 19:17, 10 July 2024
protein-coupled receptors (GPCRs), also known as seven-(pass)-transmembrane domain receptors, 7TM receptors, heptahelical receptors, serpentine receptors, and G...
82 KB (9,384 words) - 18:56, 11 June 2024
only the transmembrane regions of the receptors are considered, amino acid similarity between the two receptor subtypes is approximately 68%. In addition...
32 KB (3,086 words) - 22:54, 27 June 2024