Infliximab, a chimeric monoclonal antibody, sold under the brand name Remicade among others, is a medication used to treat a number of autoimmune diseases...
46 KB (4,047 words) - 21:12, 30 June 2024
not infectious. Treatments may include corticosteroids, ciclosporin, infliximab, or canakinumab. The disease was identified in 1930. It affects approximately...
14 KB (1,417 words) - 05:19, 12 August 2024
of a monoclonal antibody to be approved worldwide was a biosimilar of infliximab in the EU in 2013. On March 6, 2015, the FDA approved the United States'...
95 KB (6,480 words) - 22:51, 13 May 2024
1988, a monoclonal antibody called infliximab was discovered at New York University's School of Medicine. Infliximab works by binding to TNF, stopping...
28 KB (3,327 words) - 19:25, 25 July 2024
such as infliximab from binding antigen in a laboratory test. Specifically, neutralization occurs when the anti-drug antibody binds to infliximab's antigen...
116 KB (12,975 words) - 22:38, 2 September 2024
Management of Crohn's disease (section Infliximab)
disease A combination of azathioprine and infliximab treatment may be more effective than a single dose of infliximab to induce steroid-free remission for...
44 KB (4,617 words) - 19:57, 12 September 2024
Inhibition of TNF effects can be achieved with a monoclonal antibody such as infliximab, adalimumab, certolizumab pegol, and golimumab, or with a circulating...
33 KB (3,686 words) - 07:30, 20 May 2024
allergies, azathioprine and antibodies, including mepolizumab, omalizumab, infliximab, and adalimumab. The word enteritis (/ˌɛntəˈraɪtɪs/) uses combining forms...
19 KB (1,909 words) - 11:30, 29 April 2024
(disease-modifying antirheumatic drugs), monoclonal antibodies, such as infliximab and adalimumab, the TNF inhibitor etanercept, and methotrexate for moderate...
15 KB (1,475 words) - 17:04, 29 July 2024
Calcipotriol Calcipotriol plus betamethasone dipropionate ointment. Efalizumab Infliximab Golimumab Low dose methotrexate Intralesional corticosteroid injection...
14 KB (1,415 words) - 13:11, 3 September 2024
fistulas will need surgery to fix. Medications such as antibiotics and Infliximab may be prescribed to help close the rectovaginal fistula or prepare for...
7 KB (642 words) - 03:02, 22 March 2024
develop in patients undergoing autoimmune disease therapy with the drug infliximab. This drug can cause the patient to develop antibodies to the medicine...
858 bytes (85 words) - 11:30, 30 August 2023
pathogen entry into cells to prevent further infection and replication. Infliximab is a monoclonal antibody binding with tumour necrosis factor-alpha (TNF-alpha)...
33 KB (3,822 words) - 15:39, 25 July 2024
active disease. Use of certain medications, such as corticosteroids and infliximab (an anti-αTNF monoclonal antibody), is another important risk factor,...
165 KB (16,712 words) - 15:07, 12 September 2024
binding protein is a monoclonal antibody or a circulating receptor such as infliximab (Remicade), etanercept (Enbrel), or adalimumab (Humira) that binds to...
29 KB (3,378 words) - 13:22, 5 September 2024
anakinra, tocilizumab, cyclophosphamide, adalimumab, rituximab, and infliximab. Newer medications target interleukin-1 (IL-1), particularly IL-1β. A...
17 KB (1,757 words) - 08:18, 25 August 2024
Trastuzumab Monoclonal antibodies used for autoimmune diseases include infliximab and adalimumab, which are effective in rheumatoid arthritis, Crohn's disease...
49 KB (4,964 words) - 04:02, 9 August 2024
patients with inflammatory bowel disease. TNF-α Inhibitor treatments (infliximab, adalimumab, certolizumab, natalizumab, and etanercept) are thought to...
162 KB (18,422 words) - 04:18, 12 September 2024
promote tumor survival, invasion, and metastasis. TNF-blockers such as infliximab and etanercept did not induce a response in most advanced or metastatic...
68 KB (8,832 words) - 08:43, 7 September 2024
often used for severe disease manifestations. Anti-TNF therapy such as infliximab has shown promise in treating the uveitis associated with the disease...
46 KB (5,149 words) - 22:14, 7 September 2024
simvastatin for high-risk, post-acute-coronary-syndrome patients. Remicade (infliximab) is a monoclonal antibody directed toward the cytokine TNF-alpha and used...
96 KB (9,413 words) - 14:30, 14 September 2024
molecules (e.g., atorvastatin, fluticasone, clopidogrel) and "biologics" (infliximab, erythropoietin, insulin glargine), the latter of which are most often...
16 KB (1,943 words) - 03:31, 24 June 2024
similar to that seen with infliximab, but as adalimumab has better tolerability profile it may be preferred over infliximab. Ursodeoxycholic acid has...
118 KB (12,860 words) - 03:15, 27 August 2024
sometimes ciclosporin. Many anti-inflammatory biological mediators, such as infliximab, etanercept, and anakinra are being tried. In January 2020, the US Food...
29 KB (2,836 words) - 04:03, 24 June 2024
leflunomide, hydroxychloroquine, TNF inhibitors (certolizumab, adalimumab, infliximab and etanercept), abatacept, anakinra, and auranofin. Additionally, rituximab...
147 KB (15,992 words) - 01:02, 12 September 2024
from biological blockade using the TNFa antagonists etanercept and infliximab. Infliximab is also useful in reducing spondyloarthropathy and intestinal inflammation...
29 KB (2,841 words) - 05:02, 9 August 2024
Biologics prescribed for psoriatic arthritis are TNF-α inhibitors, including infliximab, etanercept, golimumab, certolizumab pegol and adalimumab, as well as...
32 KB (3,438 words) - 14:55, 9 July 2024
hydroxychloroquine, cyclophosphamide, pentoxifylline, thalidomide and infliximab have been reported to be effective in small studies. In patients unresponsive...
18 KB (2,010 words) - 21:37, 3 December 2023
induce apoptosis of inflammatory cells and decrease chemotaxis csDMARD infliximab TNF inhibitor bDMARD leflunomide Pyrimidine synthesis inhibitor csDMARD...
10 KB (869 words) - 17:44, 20 August 2024
Vandergheynst F, Decaux G (2008). "Inefficacy of intravenous immunoglobulins and infliximab in Degos' disease". Acta Clin Belg. 63 (2): 99–102. doi:10.1179/acb.2008...
14 KB (1,651 words) - 12:26, 6 August 2024