• Thumbnail for Interferon gamma
    Interferon gamma (IFNG or IFN-γ) is a dimerized soluble cytokine that is the only member of the type II class of interferons. The existence of this interferon...
    56 KB (6,483 words) - 16:47, 27 December 2024
  • Thumbnail for Interferon
    significantly enhance the presentation of MHC I dependent antigens. Interferon gamma (IFN-gamma) also significantly stimulates the MHC II-dependent presentation...
    62 KB (7,065 words) - 11:04, 1 January 2025
  • Thumbnail for Interferon-gamma receptor
    The interferon-gamma receptor (IFNGR) protein complex is the heterodimer of two chains: IFNGR1 and IFNGR2. It binds interferon-γ, the sole member of interferon...
    8 KB (870 words) - 23:14, 28 May 2024
  • Interferon-γ release assays (IGRA) are medical tests used in the diagnosis of some infectious diseases, especially tuberculosis. Interferon-γ (IFN-γ)...
    4 KB (583 words) - 20:36, 8 July 2024
  • Thumbnail for Diagnosis of tuberculosis
    et al. (September 2007). "Usefulness of whole-blood interferon-gamma assay and interferon-gamma enzyme-linked immunospot assay in the diagnosis of active...
    48 KB (5,466 words) - 06:30, 21 October 2024
  • Thumbnail for Interferon gamma receptor 1
    Interferon gamma receptor 1 (IFNGR1) also known as CD119 (Cluster of Differentiation 119), is a protein that in humans is encoded by the IFNGR1 gene. The...
    12 KB (1,390 words) - 22:37, 2 April 2024
  • Thumbnail for Cell-mediated immunity
    chemokines CXCL9, CXCL10 and CXCL11 in response to interferon gamma. Additionally, interferon gamma secreted by these cells seems to be important in downregulating...
    14 KB (1,377 words) - 16:49, 20 November 2024
  • Thumbnail for Interferon type I
    The type-I interferons (IFN) are cytokines which play essential roles in inflammation, immunoregulation, tumor cells recognition, and T-cell responses...
    24 KB (2,934 words) - 03:44, 16 December 2024
  • Thumbnail for Cytokine
    Interferon-alpha, an interferon type I, was identified in 1957 as a protein that interfered with viral replication. The activity of interferon-gamma (the...
    35 KB (3,949 words) - 11:35, 2 January 2025
  • Thumbnail for Interleukin 10
    IL-22, IL-24 (Mda-7), IL-26 and interferons type-I (IFN-alpha, -beta, -epsilon, -kappa, -omega), type-II (IFN-gamma) and type-III (IFN-lambda, including...
    40 KB (4,619 words) - 06:54, 7 November 2024
  • responses to some cytokines, such as interferon-gamma. JAK1 and JAK2 are involved in type II interferon (interferon-gamma) signalling, whereas JAK1 and TYK2...
    9 KB (974 words) - 14:46, 22 June 2024
  • (SERPINA12) progranulin CTRP-4 Interleukin 8 (IL-8), interleukin 10 (IL-10), interferon gamma (IFN-γ) and inducible protein 10 (IP-10 or CXCL10) have been shown...
    4 KB (443 words) - 07:08, 27 April 2024
  • Pegylated interferon alfa-2a, sold under the brand name Pegasys among others, is medication used to treat hepatitis C and hepatitis B. For hepatitis C...
    11 KB (905 words) - 00:05, 5 September 2024
  • Interferon alfa (INN) or HuIFN-alpha-Le, trade name Multiferon, is a pharmaceutical drug composed of natural interferon alpha (IFN-α), obtained from the...
    7 KB (662 words) - 22:43, 14 September 2024
  • Thumbnail for PD-L1
    treatment with interferon-gamma, miR-513 was down-regulated, thereby lifting suppression of PD-L1 protein. In this way, interferon-gamma can induce PD-L1...
    25 KB (3,052 words) - 15:34, 14 September 2024
  • complete deficiency in the interferon-gamma receptor have significant elevations in plasma concentrations of interferon-gamma, which can be measured by...
    14 KB (1,413 words) - 03:44, 11 October 2023
  • created to make cytokines, like interferon gamma, that activate macrophages and cytotoxic T lymphocytes (CTLs). Interferon gamma represents an example of pluripotency...
    4 KB (490 words) - 23:43, 5 March 2023
  • Thumbnail for Interferon beta-1a
    Interferon beta-1a (also interferon beta 1-alpha) is a cytokine in the interferon family used to treat multiple sclerosis (MS). It is produced by mammalian...
    32 KB (2,851 words) - 23:22, 16 August 2024
  • (IL-1), IL-6, IL-12, and IL-18, tumor necrosis factor alpha (TNF-α), interferon gamma (IFNγ), and granulocyte-macrophage colony stimulating factor (GM-CSF)...
    20 KB (2,244 words) - 10:26, 2 December 2024
  • Interferon beta-1b is a cytokine in the interferon family used to treat the relapsing-remitting and secondary-progressive forms of multiple sclerosis (MS)...
    13 KB (1,292 words) - 19:17, 6 April 2024
  • Thumbnail for Interferon gamma receptor 2
    Interferon gamma receptor 2 also known as IFN-γR2 is a protein which in humans is encoded by the IFNGR2 gene. This gene (IFNGR2) encodes the non-ligand-binding...
    2 KB (245 words) - 00:15, 8 October 2023
  • Interferon alfa-2b is an antiviral or antineoplastic drug. It is a recombinant form of the protein Interferon alpha-2 that was originally sequenced and...
    10 KB (793 words) - 08:11, 15 September 2024
  • Interferon-gamma release assays (IGRAs) are diagnostic tools for latent tuberculosis infection (LTBI). They are surrogate markers of Mycobacterium tuberculosis...
    21 KB (2,680 words) - 05:55, 20 October 2024
  • of interferon signaling. interferon-alpha/beta receptor interferon-gamma receptor Interferon type III receptor Interleukin-10 receptor Interleukin-20...
    6 KB (616 words) - 18:29, 7 June 2023
  • antidepressant bupropion lowers production of tumor necrosis factor-alpha and interferon-gamma in mice". International Immunopharmacology. 6 (6): 903–907. doi:10...
    33 KB (3,686 words) - 17:04, 29 December 2024
  • Thumbnail for Tuberculosis
    Hodgkin's lymphoma, malnutrition, and most notably, active tuberculosis. Interferon gamma release assays, on a blood sample, are recommended in those who are...
    166 KB (16,894 words) - 05:55, 30 December 2024
  • Thumbnail for STAT1
    Specifically STAT1 can be activated by several ligands such as Interferon alpha (IFNα), Interferon gamma (IFNγ), Epidermal Growth Factor (EGF), Platelet Derived...
    31 KB (3,768 words) - 23:07, 20 December 2024
  • Thumbnail for Interferon gamma receptor (IFNGR1) family
    biology, the interferon gamma receptor (IFNGR1) family is a family of proteins which includes several eukaryotic and viral interferon gamma receptor proteins...
    3 KB (313 words) - 20:28, 22 December 2020
  • Thumbnail for Natural killer cell
    functions; often, NKT cell activity promotes NK cell activity by secreting interferon gamma. In contrast to NKT cells, NK cells do not express T-cell antigen receptors...
    75 KB (9,227 words) - 23:32, 16 October 2024
  • Thumbnail for Mantoux test
    addition to tuberculin skin tests such as (principally) the Mantoux test, interferon gamma release assays (IGRAs) have become common in clinical use in the 2010s...
    23 KB (2,616 words) - 16:06, 19 December 2024