Statins (or HMG-CoA reductase inhibitors) are a class of medications that lower cholesterol. They are prescribed typically to people who are at high risk...

HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase inhibitors, called statins, was a breakthrough in the prevention of hypercholesterolemia and related...

Atorvastatin is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. For the prevention...

Generally it is used together with dietary changes and a statin. Alone, it is less preferred than a statin. It is taken by mouth. It is also available in the...

Rosuvastatin, sold under the brand name Crestor among others, is a statin medication, used to prevent cardiovascular disease in those at high risk and...

an adjunctive therapy to reduce inflammation in periodontitis. Although statins may reduce CoQ10 in the blood it is unclear if they reduce CoQ10 in muscle...

Hydroxymethylglutaryl-coenzyme A reductase inhibitors (HMG-CoA inhibitors or statins) Statins may sometimes cause myalgia and cramps among other possible side effects...

Statin-associated autoimmune myopathy (SAAM), also known as anti-HMGCR myopathy, is a very rare form of muscle damage caused by the immune system in people...

commonly used compared to statins because it treats a different type of cholesterol abnormality to statins. While statins have strong evidence for reducing...

the United States and other countries. Lovastatin and other prescription statin drugs inhibit cholesterol synthesis by blocking action of the enzyme HMG-CoA...

Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. It is used along with exercise, diet, and...

with a statin or statin with other lipid-lowering therapies in patients unable to reach LDL-C goals with the maximum tolerated dose of a statin; or alone...

widely available cholesterol-lowering drugs known collectively as the statins, which help treat dyslipidemia. HMG-CoA reductase is anchored in the membrane...

low risk, the use of statin therapy depends on individual patient factors such as age, cholesterol levels, and risk factors. Statins are considered the...

begins with the mevalonate or HMG-CoA reductase pathway, the target of statin drugs, which encompasses the first 18 steps. This is followed by 19 additional...

specifically PPARα, to decrease free fatty acid production. Statin drugs, especially the synthetic statins (atorvastatin and rosuvastatin) can decrease LDL levels...

Erythromycin is an antibiotic used for the treatment of a number of bacterial infections. This includes respiratory tract infections, skin infections,...

with a statin or statin with other lipid-lowering therapies in people unable to reach LDL-C goals with the maximum tolerated dose of a statin, or alone...

and beta-blockers.   Antihyperlipidemic agents most often prescribed are statins, ezetimibe and fibrates. They either lower low-density lipoprotein cholesterol...

2018 by the American College of Cardiology & American Heart Association. Statins (HMG-CoA reductase inhibitors) are particularly well suited for lowering...

cholesterol levels in the blood. Statins are the typically used medications, in addition to healthy lifestyle interventions. Statins can reduce total cholesterol...

(2015-10-13). "Clinical Effectiveness of Statin Therapy After Ischemic Stroke: Primary Results From the Statin Therapeutic Area of the Patient-Centered...

the treatment of high cholesterol and high blood pressure. It contains a statin and a calcium channel blocker. Amlodipine/atorvastatin is marketed under...

sudden cardiac deaths in stable coronary heart disease patients not using statins. Clarithromycin has been known to cause jaundice, cirrhosis, and kidney...

relationship between fungi and cholesterol biosynthesis led to the development of statin drugs, which are some of the best-selling pharmaceuticals in history. Endo...

trial designed to assess the efficacy of niacin (extended-release) added to statin therapy in reducing cardiovascular events in patients with established atherosclerotic...

Pravastatin, sold under the brand name Pravachol among others, is a statin medication, used for preventing cardiovascular disease in those at high risk...

]] [[ ]] [[ ]] [[ ]] [[ ]] |alt=Statin pathway edit]] The interactive pathway map can be edited at WikiPathways: "Statin_Pathway_WP430". Diglyceride acyltransferase...

particles, with or without high LDL-C levels. Fibrates may be compared to statin drugs, which reduce LDL-cholesterol (LDL-C) and have only limited effects...

for decreasing the risk of cardiovascular disease in those already on a statin. A 2010 review had concluded that niacin was effective as a mono-therapy...