U.S. Route 281 (US 281) is a north–south United States Numbered Highway. At 1,875 miles (3,018 km) it is the longest continuous three-digit U.S. Route...

U.S. Route 281 (US 281) is a United States Numbered Highway that runs from the Mexican border in the Rio Grande Valley to the Canadian border near Dunseith...

U.S. Route 281 Alternate may refer to: U.S. Route 281 Alternate (Texas), an alternate route of U.S. Route 281 in South Texas U.S. Route 281 Alternate...

U.S. Route 281 (US-281) is a part of the U.S. Highway System that runs from near the Mexican border north to the International Peace Garden, north of Dunseith...

west-northwest, meets U.S. Route 20 near Inman and the two routes overlap until US 275 ends at an intersection with U.S. Route 281 in downtown O'Neill....

U.S. Route 281 (US 281) is a part of the U.S. Highway System that travels from Hidalgo, Texas and Brownsville, Texas, to its northern terminus at the International...

with U.S. Route 283 and U.S. Route 183. At Medicine Lodge, it intersects U.S. Route 281. It continues east and at Wellington, intersects U.S. Route 81 and...

U.S. Route 277 (US 277, US-277) is a north–south United States Highway that is a spur route of U.S. Route 77. It no longer connects to its parent route...

Alternate U.S. Highway 281 (Alt. US 281) is a loop of the U.S. Highway System. The highway serves the small communities of Whitsett and Campbellton, about...

U.S. Route 380 (US 380) is an east–west United States highway. The highway's eastern terminus is in Greenville, Texas at an intersection with Interstate...

needed] it is the second longest three-digit U.S. Route, behind US 281. It serves as the major truck route between Dallas-Fort Worth and Amarillo, Texas...

U.S. Route 180 is an east–west United States highway. Like many three-digit routes, US 180 no longer meets its "parent", US 80. US 80 was decommissioned...

U.S. Route 212 (US 212) is a spur of US 12. It runs for 949 miles (1,527 km) from Yellowstone National Park to Minnesota Highway 62 at Edina, Minnesota...

U.S. Route 136 is an east-west U.S. highway that is a spur route of U.S. Route 36. It runs from Edison, Nebraska, at U.S. Route 6 and U.S. Route 34 to...

U.S. Route 82 (US 82) is an east–west United States highway in the Southern United States. Created on July 1, 1931 across central Mississippi and southern...

U.S. Route 150 (US 150) is a 571-mile (919 km) long northwest–southeast United States highway, signed as east–west. It runs from U.S. Route 6 outside...

U.S. Route 20 or U.S. Highway 20 (US 20) is an east–west United States Numbered Highway that stretches from the Pacific Northwest east to New England....

resort/retirement town near the Mexico–U.S. border. Alamo is one of the Rio Grande Valley's gateways to Mexico, via U.S. Route 281 and Nuevo Progreso, Tamaulipas...

U.S. Highway 159 (US 159) is a 83.6-mile-long (134.5 km) auxiliary route of US 59. It travels from Nortonville, Kansas at US 59 to New Point, Missouri...

U.S. Route 283 is a spur of U.S. Route 83. It currently runs for 731 miles (1,175 km) from Brady, Texas at U.S. Route 87 to Lexington, Nebraska at U.S...

U.S. Route 550 (US 550) is a spur of U.S. Highway 50 that runs from Bernalillo, New Mexico to Montrose, Colorado in the western United States. The section...

70333°N 98.12028°W / 31.70333; -98.12028 (31.703274, –98.120359). U.S. Route 281 passes through the center of the city, leading north 21 miles (34 km)...

U.S. Route 290 (US 290) is an east–west U.S. Highway located entirely within the state of Texas. Its western terminus is at Interstate 10 southeast of...

intersection of AA Road and K-191. It is accessible by a turn-off from U.S. Route 281. It is distinct from the geographic center of the 50 United States located...

U.S. Route 34 (US 34) is an east–west United States highway that runs for 1,122 miles (1,806 km) from north-central Colorado to the western suburbs of...

U.S. Route 64 (US 64) is an east–west United States highway that runs for 2,281 miles (3,672 km) from Nags Head in eastern North Carolina to just southwest...

U.S. Route 14 or U.S. Highway 14 (US 14), an east–west route, is one of the original United States Numbered Highways of 1926. It currently has a length...

Business US 281-W (Bus. US 281-W), which continues north on a reunited North Cage Boulevard through central Edinburg on US 281's former routing; meanwhile...

U.S. Route 59 (US 59) is a north–south United States highway (though it was signed east–west in parts of Texas). A latecomer to the U.S. numbered route...

U.S. Route 81 or U.S. Highway 81 (US 81) is a major north–south U.S. highway that extends for 1,220 miles (1,960 km) in the central United States and...