An antibody (Ab) or immunoglobulin (Ig) is a large, Y-shaped protein belonging to the immunoglobulin superfamily which is used by the immune system to...
119 KB (13,400 words) - 17:29, 29 August 2024
A monoclonal antibody (mAb, more rarely called moAb) is an antibody produced from a cell lineage made by cloning a unique white blood cell. All subsequent...
48 KB (4,964 words) - 23:05, 30 September 2024
anti-Ro antibodies, anti-La antibodies, anti-Sm antibodies, anti-nRNP antibodies, anti-Scl-70 antibodies, anti-dsDNA antibodies, anti-histone antibodies, antibodies...
54 KB (6,097 words) - 21:43, 28 June 2024
Recombinant antibodies are antibody fragments produced by using recombinant antibody coding genes. They mostly consist of a heavy and light chain of the...
28 KB (3,348 words) - 12:40, 6 August 2024
A neutralizing antibody (NAb) is an antibody that defends a cell from a pathogen or infectious particle by neutralizing any effect it has biologically...
32 KB (3,494 words) - 00:52, 30 July 2024
Immunoglobulin G (redirect from IgG antibody)
(IgG) is a type of antibody. Representing approximately 75% of serum antibodies in humans, IgG is the most common type of antibody found in blood circulation...
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Antiphospholipid syndrome (redirect from Antiphospholipid antibodies)
or antiphospholipid antibody syndrome (APS or APLS), is an autoimmune, hypercoagulable state caused by antiphospholipid antibodies. APS can lead to blood...
37 KB (3,944 words) - 17:43, 30 September 2024
Antibody opsonization is a process by which a pathogen is marked for phagocytosis through coating of a target cell with antibodies. Immunoglobulins participate...
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Antigen (redirect from Antibody generator)
antibodies are antigen-specific, meaning that an antibody can only react to and bind one specific antigen; in some instances, however, antibodies may...
20 KB (2,435 words) - 03:32, 7 October 2024
Antibody–drug conjugates or ADCs are a class of biopharmaceutical drugs designed as a targeted therapy for treating cancer. Unlike chemotherapy, ADCs are...
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An antibody elution is a clinical laboratory diagnostic procedure which removes sensitized antibodies from red blood cells, in order to determine the blood...
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Antigen-antibody interaction, or antigen-antibody reaction, is a specific chemical interaction between antibodies produced by B cells of the white blood...
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Immunofluorescence (redirect from Fluorescent antibody technique)
specificity of antibodies and antigens. The specific region an antibody recognizes on an antigen is called an epitope. Several antibodies can recognize...
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Coombs test (redirect from Coombs antibody)
The direct Coombs test detects antibodies that are stuck to the surface of the red blood cells. Since these antibodies sometimes destroy red blood cells...
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matching antibody is applied over the surface so it can bind the antigen. This antibody is linked to an enzyme and then any unbound antibodies are removed...
37 KB (4,786 words) - 04:41, 24 June 2024
Western blot (section Primary antibody)
the primary antibody, before excess antibody is washed off. A secondary antibody is added which recognizes and binds to the primary antibody. The secondary...
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Antibody-dependent cellular cytotoxicity (ADCC), also referred to as antibody-dependent cell-mediated cytotoxicity, is a mechanism of cell-mediated immune...
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Primary and secondary antibodies are two groups of antibodies that are classified based on whether they bind to antigens or proteins directly or target...
4 KB (452 words) - 19:14, 30 January 2021
Humanized antibodies are antibodies from non-human species whose protein sequences have been modified to increase their similarity to antibody variants...
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Humoral immunity (redirect from Antibody-mediated immunity)
aspect of immunity that is mediated by macromolecules – including secreted antibodies, complement proteins, and certain antimicrobial peptides – located in...
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Neuromyelitis optica spectrum disorder (redirect from NMO antibodies)
the neurologic structures the disease affects, and, to some extent, the antibodies involved. The most common initial manifestation of the disease is inflammation...
68 KB (7,285 words) - 22:42, 21 September 2024
Antithyroid autoantibodies (redirect from Antimicrosomal antibody test)
anti-thyroid peroxidase antibodies (anti-TPO antibodies, TPOAb), thyrotropin receptor antibodies (TRAb) and thyroglobulin antibodies (TgAb). TRAb's are subdivided...
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antibody (sdAb), also known as a Nanobody, is an antibody fragment consisting of a single monomeric variable antibody domain. Like a whole antibody,...
35 KB (3,898 words) - 14:53, 18 May 2024
heavy-chain antibody is an antibody which consists only of two heavy chains and lacks the two light chains usually found in antibodies. In common antibodies, the...
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A bispecific monoclonal antibody (BsMAb, BsAb) is an artificial protein that can simultaneously bind to two different types of antigen or two different...
30 KB (3,405 words) - 20:39, 11 October 2024
Antibody-dependent enhancement (ADE), sometimes less precisely called immune enhancement or disease enhancement, is a phenomenon in which binding of a...
42 KB (4,831 words) - 09:43, 1 October 2024
anti-mitochondrial antibody. In SLE, anti-DNA antibodies and anti-cardiolipin antibodies may be present individually or together; the two types of antibodies act independently...
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Diagnosis of HIV/AIDS (redirect from HIV antibody test)
that causes HIV/AIDS, in serum, saliva, or urine. Such tests may detect antibodies, antigens, or RNA. AIDS is diagnosed separately from HIV. The eclipse...
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Heterophile antibodies are antibodies induced by external antigens that may be shared between species and are not well defined (heterophile antigens)...
7 KB (912 words) - 01:54, 23 August 2024
Immunoglobulin M (redirect from IgM antibodies)
of several isotypes of antibodies (also known as immunoglobulin) that are produced by vertebrates. IgM is the first antibody to appear in the response...
35 KB (4,043 words) - 03:54, 24 May 2024