• Pattern recognition receptors (PRRs) play a crucial role in the proper function of the innate immune system. PRRs are germline-encoded host sensors, which...
    43 KB (5,173 words) - 21:02, 10 August 2024
  • in the host. They are recognized by toll-like receptors (TLRs) and other pattern recognition receptors (PRRs) in both plants and animals. This allows...
    13 KB (1,476 words) - 12:50, 13 January 2024
  • neuroscience, pattern recognition describes a cognitive process that matches information from a stimulus with information retrieved from memory. Pattern recognition...
    35 KB (4,573 words) - 15:07, 13 July 2024
  • Thumbnail for Toll-like receptor
    on interacting with TLR5 on human T cells. TLRs are a type of pattern recognition receptor (PRR) and recognize molecules that are broadly shared by pathogens...
    61 KB (6,763 words) - 16:03, 3 September 2024
  • Thumbnail for RIG-I
    RIG-I (category RIG-I-like receptors)
    RIG-I (retinoic acid-inducible gene I) is a cytosolic pattern recognition receptor (PRR) that can mediate induction of a type-I interferon (IFN1) response...
    23 KB (2,831 words) - 16:57, 27 August 2024
  • receptors (retinoic acid-inducible gene-I-like receptors, RLRs) are a type of intracellular pattern recognition receptor involved in the recognition of...
    25 KB (3,011 words) - 17:07, 24 May 2024
  • Thumbnail for Viral strategies for immune response evasion
    cells utilize specialized receptors known as Pattern Recognition Receptors(PRRs) to detect viral infection; these receptors are able to recognize pathogen-associated...
    8 KB (1,059 words) - 14:12, 24 January 2024
  • Thumbnail for C-reactive protein
    protein C (blood coagulation). C-reactive protein was the first pattern recognition receptor (PRR) to be identified. Discovered by Tillett and Francis in...
    47 KB (5,296 words) - 20:17, 16 August 2024
  • Thumbnail for Toll-like receptor 4
    gene. TLR4 belongs to the toll-like receptor family which is representative of the pattern recognition receptors (PRR), so named for their ability to...
    75 KB (9,082 words) - 10:46, 12 June 2024
  • Thumbnail for CLEC7A
    immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor for a variety of β-1,3-linked and β-1,6-linked glucans from fungi...
    15 KB (1,690 words) - 13:18, 4 January 2024
  • Thumbnail for EF-Tu receptor
    EF-Tu receptor, abbreviated as EFR, is a pattern-recognition receptor (PRR) that binds to the prokaryotic protein EF-Tu (elongation factor thermo unstable)...
    12 KB (1,511 words) - 12:42, 27 December 2023
  • Thumbnail for MDA5
    MDA5 (category RIG-I-like receptors)
    family, which also includes RIG-I and LGP2, and functions as a pattern recognition receptor capable of detecting viruses. It is generally believed that MDA5...
    18 KB (2,222 words) - 09:48, 7 July 2024
  • Thumbnail for RAGE (receptor)
    through a common structural motif, RAGE is often referred to as a pattern recognition receptor. RAGE also has at least one other agonistic ligand: high mobility...
    19 KB (2,337 words) - 03:47, 26 April 2024
  • essential for pathogen defense are pattern recognition receptors (PRRs), wall associated kinase (WAKs), receptors with nucleotide-binding domain (NLRs)...
    18 KB (2,099 words) - 18:35, 12 August 2024
  • Thumbnail for Pamela Ronald
    the Ronald laboratory isolated and characterized the rice XA21 pattern recognition receptor. Subsequent discoveries in flies, humans, mice, and Arabidopsis...
    45 KB (4,306 words) - 01:23, 9 July 2024
  • Thumbnail for Danger model
    being activated by pattern recognition receptors (PRRs) that recognize evolutionarily conserved pathogen-associated molecular patterns (PAMPs) as infectious...
    11 KB (1,153 words) - 15:53, 1 September 2024
  • via the phagocytic pathway. In this way, the mannose receptor acts as a pattern recognition receptor. The presence of a di-aromatic FENTLY (Phe-Glu-Asn-Thr-Leu-Tyr)...
    32 KB (3,688 words) - 06:43, 3 June 2024
  • promotes a noninfectious inflammatory response by binding to a pattern recognition receptor (PRR). Inflammation is a key aspect of the innate immune response;...
    35 KB (3,558 words) - 10:17, 24 July 2024
  • Thumbnail for Immune receptor
    receptors in the immune system are pattern recognition receptors (PRRs), Toll-like receptors (TLRs), killer activated and killer inhibitor receptors (KARs...
    2 KB (113 words) - 22:22, 12 July 2023
  • Thumbnail for Innate immune system
    mast cells. These cells present receptors contained on the surface or within the cell, named pattern recognition receptors (PRRs), which recognize molecules...
    43 KB (4,797 words) - 03:20, 11 July 2024
  • Thumbnail for NOD2
    NOD2 (category NOD-like receptors)
    and stimulates an immune reaction. NOD2 is an intracellular pattern recognition receptor, which is similar in structure to resistant proteins of plants...
    13 KB (1,530 words) - 16:58, 31 August 2024
  • Thumbnail for Toll-like receptor 6
    family, which belongs to the pattern recognition receptor (PRR) family. TLR6 acts in a heterodimer form with toll-like receptor 2 (TLR2). Its ligands include...
    8 KB (1,073 words) - 21:43, 4 April 2024
  • Thumbnail for Toll-like receptor 1
    Toll-like receptor 1 (TLR1) is a member of Toll-like receptors (TLRs), which is a family of pattern recognition receptors (PRRs) that form the cornerstone...
    12 KB (1,377 words) - 21:42, 4 April 2024
  • Thumbnail for MARCO
    MARCO (category Scavenger receptors)
    found on particular subsets of macrophages. Scavenger receptors are pattern recognition receptors (PRRs) found most commonly on immune cells. Their defining...
    21 KB (2,232 words) - 05:14, 2 January 2024
  • Thumbnail for CD14
    CD14 was the first described pattern recognition receptor. CD14 acts as a co-receptor (along with the Toll-like receptor TLR 4 and MD-2) for the detection...
    7 KB (845 words) - 09:05, 27 March 2024
  • Thumbnail for CpG oligodeoxynucleotide
    genomes. The CpG PAMP is recognized by the pattern recognition receptor (PRR) Toll-Like Receptor 9 (TLR9), which is constitutively expressed only in...
    11 KB (1,393 words) - 18:39, 23 February 2024
  • Thumbnail for Toll-like receptor 3
    by the TLR3 gene. TLR3 is a member of the toll-like receptor family of pattern recognition receptors of the innate immune system. TLR3 recognizes double-stranded...
    9 KB (1,027 words) - 06:24, 13 September 2024
  • Thumbnail for Immune system
    response is usually triggered when microbes are identified by pattern recognition receptors, which recognize components that are conserved among broad groups...
    118 KB (13,486 words) - 16:39, 9 September 2024
  • CD3δ / two CD3ε ζ-chain (CD247, CD3ζ, TCRζ) Pattern recognition receptor Membrane-bound PRRs Toll-like receptors (TLRs) TLR1 TLR2 TLR3 TLR4 TLR5 TLR6 TLR7...
    38 KB (2,656 words) - 12:11, 30 October 2023
  • Thumbnail for Receptor (biochemistry)
    is the receptor that is not responding sufficiently to the hormone. The main receptors in the immune system are pattern recognition receptors (PRRs),...
    26 KB (2,672 words) - 14:14, 22 July 2024