The terms glycans and polysaccharides are defined by IUPAC as synonyms meaning "compounds consisting of a large number of monosaccharides linked glycosidically"...
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N-linked glycosylation (redirect from N-glycan)
carbohydrate consisting of several sugar molecules, sometimes also referred to as glycan, to a nitrogen atom (the amide nitrogen of an asparagine (Asn) residue of...
25 KB (2,510 words) - 20:41, 27 September 2024
Glycan arrays, like that offered by the Consortium for Functional Glycomics (CFG), National Center for Functional Glycomics (NCFG) and Z Biotech, LLC,...
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cell. In contrast, perturbation of glycan processing (enzymatic removal/addition of carbohydrate residues to the glycan), which occurs in both the endoplasmic...
28 KB (2,653 words) - 04:14, 23 July 2024
Glycan nomenclature is the systematic naming of glycans, which are carbohydrate-based polymers made by all living organisms. In general glycans can be...
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Nomenclature For Glycans (SNFG) is a community-curated standard for the depiction of simple monosaccharides and complex carbohydrates (glycans) using various...
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Glycosylation is the reaction in which a carbohydrate (or 'glycan'), i.e. a glycosyl donor, is attached to a hydroxyl or other functional group of another...
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O-linked glycosylation (redirect from O-linked glycan)
ways by changing protein stability and regulating protein activity. O-glycans, which are the sugars added to the serine or threonine, have numerous functions...
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Glycan-Protein interactions represent a class of biomolecular interactions that occur between free or protein-bound glycans and their cognate binding...
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the structure, biosynthesis, and biology of saccharides (sugar chains or glycans) that are widely distributed in nature. Sugars or saccharides are essential...
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systematic study of all glycan structures of a given cell type or organism" and is a subset of glycobiology. "Carbohydrate", "glycan", "saccharide", and "sugar"...
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Moreover, glycans can be modified (modified sugars), this increases its complexity. Complex biosynthetic pathways for glycans. Usually glycans are found...
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GlycoRNAs are small non-coding RNAs with sialylated glycans. Glycans mediate inter- and intramolecular interactions by adding polysaccharide chains onto...
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host glycans Immune recognition of glycans Glycans in immune cell communication Glycans in development and physiology Glycans in cancer biology Glycans in...
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synthetic methods developed by Wong along with his work on the development of glycan microarrays for the high-throughput analysis of protein-carbohydrate interaction...
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Glycosylphosphatidylinositol (redirect from Phosphatidylinositol glycan anchor)
Glycosylphosphatidylinositol (pronunciation) or glycophosphatidylinositol (GPI) is a phosphoglyceride that can be attached to the C-terminus of a protein...
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PIGA (redirect from Phosphatidylinositol glycan A)
N-acetylglucosaminyltransferase subunit A (PIG-A, or phosphatidylinositol glycan, class A) is the catalytic subunit of the phosphatidylinositol...
9 KB (1,106 words) - 20:03, 27 October 2023
Glycopeptide (section N-Linked glycans)
Glycopeptides are peptides that contain carbohydrate moieties (glycans) covalently attached to the side chains of the amino acid residues that constitute...
14 KB (1,528 words) - 03:08, 8 November 2023
Autoimmune disease (section Altered glycan theory)
ME, Patel F, Wilken R, et al. (February 2015). "Glycans in the immune system and The Altered Glycan Theory of Autoimmunity: a critical review". Journal...
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deoxy sugar with the chemical formula C6H12O5. It is found on N-linked glycans on the mammalian, insect and plant cell surface. Fucose is the fundamental...
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and autoreactive processes. Intelectins (X-type lectins) bind microbial glycans and may function in the innate immune system as well. Lectins may be involved...
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consistent. MIRAGE Glycan microarray guidelines for the comprehensive description of Glycan array experiments the reporting guidelines for glycan microarray analysis...
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projects are: Analysis of potential glycan-binding proteins on various glycan arrays (CFG glycan array, Microbial glycan array, NCFG-derived arrays)[clarification...
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Metabolism (section Carbohydrates and glycans)
usually being used to maintained glucose level in blood. Polysaccharides and glycans are made by the sequential addition of monosaccharides by glycosyltransferase...
113 KB (12,407 words) - 18:55, 25 September 2024
tool to help glycomics researchers to determine asparagine-linked glycan (N-glycan) structures based on collision-induced dissociation (CID) tandem mass...
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with the addition of a precursor glycan. The precursor glycan is modified in the Golgi apparatus to produce complex glycan bound covalently to the nitrogen...
40 KB (4,342 words) - 18:58, 2 April 2024
● Blue: envelope ● Turquoise: spike glycoprotein (S) ● Pink: envelope proteins (E) ● Green: membrane proteins (M) ● Orange: glycan...
122 KB (12,462 words) - 03:40, 15 August 2024
the mass of the trimeric envelope spike is N-linked glycans. The density is high as the glycans shield the underlying viral protein from neutralisation...
123 KB (14,115 words) - 13:33, 14 October 2024
include endothelin receptor antagonists, tyrosine kinase inhibitors, beta-glycan peptides, halofuginone, basiliximab, alemtuzumab, abatacept, and haematopoietic...
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considerable amount of mannose residues due to the tight clustering of glycans in its viral spike. These mannose residues are the target for broadly neutralizing...
17 KB (1,727 words) - 02:40, 16 September 2024