• Thumbnail for Hepatocyte growth factor receptor
    Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
    58 KB (6,927 words) - 03:33, 17 June 2024
  • Thumbnail for Hepatocyte growth factor
    Hepatocyte growth factor (HGF) or scatter factor (SF) is a paracrine cellular growth, motility and morphogenic factor. It is secreted by mesenchymal cells...
    23 KB (2,711 words) - 10:05, 2 June 2024
  • Artemin Growth differentiation factor-9 (GDF9) Hepatocyte growth factor (HGF) Hepatoma-derived growth factor (HDGF) Insulin Insulin-like growth factors Insulin-like...
    10 KB (1,131 words) - 19:14, 31 March 2024
  • Thumbnail for Epidermal growth factor receptor
    epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
    60 KB (6,879 words) - 09:57, 15 January 2024
  • A growth factor receptor is a receptor that binds to a growth factor. Growth factor receptors are the first stop in cells where the signaling cascade...
    5 KB (591 words) - 15:41, 29 April 2024
  • The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of...
    8 KB (827 words) - 22:08, 3 December 2023
  • Thumbnail for Nerve growth factor
    Nerve growth factor (NGF) is a neurotrophic factor and neuropeptide primarily involved in the regulation of growth, maintenance, proliferation, and survival...
    23 KB (2,786 words) - 23:53, 26 April 2024
  • Thumbnail for Insulin-like growth factor 1
    is known as mechano-growth factor (MGF). Laron syndrome (LS), also known as growth hormone insensitivity or growth hormone receptor deficiency (GHRD),...
    36 KB (4,822 words) - 06:03, 26 June 2024
  • Thumbnail for Fibroblast growth factor receptor 2
    Fibroblast growth factor receptor 2 (FGFR2) also known as CD332 (cluster of differentiation 332) is a protein that in humans is encoded by the FGFR2 gene...
    14 KB (1,748 words) - 14:34, 11 December 2023
  • Thumbnail for Platelet-derived growth factor receptor
    Platelet-derived growth factor receptors (PDGF-R) are cell surface tyrosine kinase receptors for members of the platelet-derived growth factor (PDGF) family...
    13 KB (1,563 words) - 09:00, 13 March 2024
  • Thumbnail for MST1
    Macrophage-stimulating protein (MSP), also known as hepatocyte growth factor-like protein (HLP, HGFL, or HGFLP), is a protein that in humans is encoded...
    7 KB (901 words) - 22:17, 3 March 2023
  • Thumbnail for Crizotinib
    Crizotinib (category Receptor tyrosine kinase inhibitors)
    cell lung carcinoma (NSCLC). Crizotinib inhibits the c-Met/Hepatocyte growth factor receptor (HGFR) tyrosine kinase, which is involved in the oncogenesis...
    22 KB (1,864 words) - 09:03, 1 July 2024
  • Thumbnail for Fibroblast growth factor receptor 1
    Fibroblast growth factor receptor 1 (FGFR1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
    44 KB (5,001 words) - 17:06, 4 January 2024
  • Thumbnail for Insulin-like growth factor
    The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate...
    14 KB (1,689 words) - 00:46, 6 December 2023
  • Thumbnail for Hepatocyte nuclear factor 4 alpha
    Hepatocyte nuclear factor 4 alpha (HNF4A) also known as NR2A1 (nuclear receptor subfamily 2, group A, member 1) is a nuclear receptor that in humans is...
    19 KB (2,210 words) - 12:51, 22 December 2023
  • Thumbnail for Low-affinity nerve growth factor receptor
    nerve growth factor. p75NTR is a neurotrophic factor receptor. Neurotrophic factor receptors bind Neurotrophins including Nerve growth factor, Neurotrophin-3...
    37 KB (4,235 words) - 13:48, 29 June 2024
  • Thumbnail for Platelet-derived growth factor receptor A
    Platelet-derived growth factor receptor A, also termed CD140a, is a receptor located on the surface of a wide range of cell types. The protein is encoded...
    29 KB (3,354 words) - 17:01, 9 December 2023
  • Growth factor receptor inhibitors (growth factor inhibitors, growth factor receptor blockers, growth factor blockers, growth factor receptor antagonists...
    4 KB (381 words) - 22:35, 2 December 2023
  • Thumbnail for TNF receptor superfamily
    exception of nerve growth factor (NGF), all TNFs are homologous to the archetypal TNF-alpha. In their active form, the majority of TNF receptors form trimeric...
    8 KB (501 words) - 01:30, 27 December 2023
  • Thumbnail for Insulin-like growth factor 2 receptor
    Insulin-like growth factor 2 receptor (IGF2R), also called the cation-independent mannose-6-phosphate receptor (CI-MPR) is a protein that in humans is...
    13 KB (1,664 words) - 16:27, 25 May 2024
  • Thumbnail for Fibroblast growth factor receptor 3
    Fibroblast growth factor receptor 3 is a protein that in humans is encoded by the FGFR3 gene. FGFR3 has also been designated as CD333 (cluster of differentiation...
    17 KB (1,955 words) - 06:59, 15 April 2024
  • Thumbnail for Insulin-like growth factor 1 receptor
    The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by...
    29 KB (3,603 words) - 16:26, 25 May 2024
  • Thumbnail for Tumor necrosis factor
    The binding of TNF to its receptor and its displacement by LT confirmed the functional homology between the two factors. The sequential and functional...
    52 KB (6,302 words) - 07:19, 27 April 2024
  • Thumbnail for Insulin-like growth factor 2
    Insulin-like growth factor 2 has been shown to interact with IGFBP3 and transferrin. Insulin-like growth factor 2 receptor Insulin-like growth factor II IRES...
    15 KB (1,928 words) - 06:37, 31 March 2024
  • Thumbnail for Transforming growth factor beta
    Transforming growth factor beta (TGF-β) is a multifunctional cytokine belonging to the transforming growth factor superfamily that includes three different...
    70 KB (8,485 words) - 08:12, 19 May 2024
  • Thumbnail for Basic fibroblast growth factor
    specific fibroblast growth factor receptor (FGFR) proteins, themselves a family of closely related molecules. Fibroblast growth factor protein was first...
    22 KB (2,693 words) - 04:46, 19 April 2024
  • Thumbnail for Brain-derived neurotrophic factor
    responding to this growth factor, TrkB (pronounced "Track B") and the LNGFR (for low-affinity nerve growth factor receptor, also known as p75). It may...
    45 KB (5,341 words) - 08:28, 10 June 2024
  • Thumbnail for VEGF receptor
    VEGF receptors (VEGFRs) are receptors for vascular endothelial growth factor (VEGF). There are three main subtypes of VEGFR, numbered 1, 2 and 3. Depending...
    8 KB (755 words) - 18:51, 2 November 2023
  • Vascular endothelial growth factor (VEGF, /vɛdʒˈɛf/), originally known as vascular permeability factor (VPF), is a signal protein produced by many cells...
    40 KB (4,580 words) - 05:24, 3 June 2024
  • Thumbnail for Platelet-derived growth factor
    Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
    24 KB (2,877 words) - 10:08, 2 June 2024