The insulin-like growth factors (IGFs) are proteins with high sequence similarity to insulin. IGFs are part of a complex system that cells use to communicate...
14 KB (1,689 words) - 01:31, 19 August 2024
Insulin-like growth factor 1 (IGF-1), also called somatomedin C, is a hormone similar in molecular structure to insulin which plays an important role...
35 KB (4,575 words) - 06:26, 15 December 2024
The insulin-like growth factor 1 (IGF-1) receptor is a protein found on the surface of human cells. It is a transmembrane receptor that is activated by...
29 KB (3,603 words) - 16:26, 25 May 2024
Insulin-like growth factor 2 (IGF-2) is one of three protein hormones that share structural similarity to insulin. The MeSH definition reads: "A well-characterized...
15 KB (1,932 words) - 08:59, 2 November 2024
insulin-like growth factor receptors (IGFRs) include the following two receptors: Insulin-like growth factor 1 receptor (IGF-1R) Insulin-like growth factor...
608 bytes (51 words) - 12:36, 21 February 2022
Insulin receptor substrate 1 plays a key role in transmitting signals from the insulin receptor (IR) and insulin-like growth factor 1 receptor (IGF-1)...
34 KB (4,304 words) - 07:20, 3 September 2024
Insulin-like growth factor 2 receptor (IGF2R), also called the cation-independent mannose-6-phosphate receptor (CI-MPR) is a protein that in humans is...
13 KB (1,664 words) - 16:27, 25 May 2024
The insulin receptor (IR) is a transmembrane receptor that is activated by insulin, IGF-I, IGF-II and belongs to the large class of receptor tyrosine kinase...
31 KB (3,785 words) - 19:26, 2 September 2024
epidermal growth factor receptor (EGFR; ErbB-1; HER1 in humans) is a transmembrane protein that is a receptor for members of the epidermal growth factor family...
60 KB (6,879 words) - 14:26, 16 July 2024
Fibroblast growth factor receptor 1 (FGFR-1), also known as basic fibroblast growth factor receptor 1, fms-related tyrosine kinase-2 / Pfeiffer syndrome...
44 KB (5,003 words) - 07:11, 15 October 2024
Insulin-like growth factors Insulin-like growth factor-1 (IGF-1) Insulin-like growth factor-2 (IGF-2) Interleukins IL-1- Cofactor for IL-3 and IL-6....
10 KB (1,131 words) - 19:14, 31 March 2024
The fibroblast growth factor receptors (FGFR) are, as their name implies, receptors that bind to members of the fibroblast growth factor (FGF) family of...
8 KB (827 words) - 22:08, 3 December 2023
arginine 3-IGF-1, abbreviated as IGF-1 LR3 or LR3-IGF-1, is a synthetic protein and lengthened analogue of human insulin-like growth factor 1 (IGF-1). It differs...
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Laron syndrome (redirect from Severe primary insulin-like growth factor-1 deficiency)
growth hormone insensitivity or growth hormone receptor deficiency (GHRD), is an autosomal recessive disorder characterized by a lack of insulin-like...
28 KB (2,885 words) - 18:38, 17 November 2024
dominant receptor types that are exclusive to research : the epidermal growth factor receptor, the neurotrophin receptor, and the insulin receptors. All growth...
5 KB (591 words) - 15:41, 29 April 2024
Hepatocyte growth factor receptor (HGF receptor) is a protein that in humans is encoded by the MET gene. The protein possesses tyrosine kinase activity...
59 KB (6,727 words) - 06:01, 27 October 2024
Breast development (redirect from Growth of the breast)
estrogen, and progesterone, growth hormone (GH), mostly via its secretory product, insulin-like growth factor 1 (IGF-1), and prolactin. These regulators...
59 KB (6,495 words) - 19:10, 25 November 2024
addictions. GLP-1 agonists work by activating the GLP-1 receptor. They slow gastric emptying, inhibit the release of glucagon, and stimulate insulin production...
49 KB (5,126 words) - 08:44, 2 January 2025
2009. de la Monte SM, Wands JR (February 2005). "Review of insulin and insulin-like growth factor expression, signaling, and malfunction in the central nervous...
121 KB (13,818 words) - 07:04, 26 December 2024
insulin-like growth factor-binding protein (IGFBP) serves as a transport protein for insulin-like growth factor 1 (IGF-1). Approximately 98% of IGF-1...
4 KB (468 words) - 09:09, 29 January 2023
ERBB3 (redirect from Receptor, erbb-3)
Receptor tyrosine-protein kinase erbB-3, also known as HER3 (human epidermal growth factor receptor 3), is a membrane bound protein that in humans is...
24 KB (2,816 words) - 06:51, 2 November 2024
Platelet-derived growth factor (PDGF) is one among numerous growth factors that regulate cell growth and division. In particular, PDGF plays a significant...
24 KB (2,882 words) - 16:31, 25 October 2024
leading to cell division and cell migration. Epidermal growth factor Insulin-like growth factor 1 Epithelial–mesenchymal transition Madin-Darby Canine Kidney...
23 KB (2,622 words) - 07:14, 1 January 2025
The glucagon-like peptide-1 receptor (GLP1R) is a G protein-coupled receptor (GPCR) found on beta cells of the pancreas and on neurons of the brain. It...
33 KB (4,125 words) - 18:11, 23 December 2024
Epidermal growth factor (EGF) is a protein that stimulates cell growth and differentiation by binding to its receptor, EGFR. Human EGF is 6-kDa and has...
17 KB (1,708 words) - 22:30, 15 October 2024
MTOR (redirect from FK506 binding protein 12-rapamycin associated protein 1)
protein kinase that promotes the activation of insulin receptors and insulin-like growth factor 1 receptors. mTORC2 has also been implicated in the control...
119 KB (12,661 words) - 15:12, 8 November 2024
Fibroblast growth factor receptor-like 1 is a protein that in humans is encoded by the FGFRL1 gene. The protein encoded by this gene is a member of the...
6 KB (842 words) - 01:10, 27 January 2024
specific fibroblast growth factor receptor (FGFR) proteins, themselves a family of closely related molecules. Fibroblast growth factor protein was first...
22 KB (2,698 words) - 17:05, 16 July 2024
Fibroblast growth factor 1 (FGF-1) also known as acidic fibroblast growth factor (aFGF), is a growth factor and signaling protein encoded by the FGF1 gene...
20 KB (2,311 words) - 22:01, 16 July 2024
GRB2 (redirect from Growth factor receptor-bound protein 2)
Growth factor receptor-bound protein 2, also known as Grb2, is an adaptor protein involved in signal transduction/cell communication. In humans, the GRB2...
82 KB (9,365 words) - 15:39, 31 March 2024