• Thumbnail for Protein kinase A
    In cell biology, protein kinase A (PKA) is a family of serine-threonine kinase whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA...
    27 KB (2,665 words) - 17:03, 6 April 2024
  • Thumbnail for Protein kinase
    A protein kinase is a kinase which selectively modifies other proteins by covalently adding phosphates to them (phosphorylation) as opposed to kinases...
    15 KB (1,635 words) - 23:25, 13 August 2024
  • In cell biology, Protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling...
    27 KB (2,716 words) - 12:30, 12 September 2024
  • A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses...
    46 KB (5,492 words) - 14:52, 20 August 2024
  • Thumbnail for AMP-activated protein kinase
    5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular...
    65 KB (7,149 words) - 04:45, 26 August 2024
  • Thumbnail for Protein kinase B
    Protein kinase B (PKB), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple...
    35 KB (3,831 words) - 18:08, 20 August 2024
  • Thumbnail for Serine/threonine-specific protein kinase
    A serine/threonine protein kinase (EC 2.7.11.-) is a kinase enzyme, in particular a protein kinase, that phosphorylates the OH group of the amino-acid...
    14 KB (1,210 words) - 13:35, 14 June 2024
  • Thumbnail for Tyrosine kinase
    A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to the tyrosine residues of specific proteins inside a cell. It functions as...
    43 KB (5,251 words) - 10:44, 24 June 2024
  • Thumbnail for Receptor tyrosine kinase
    unique tyrosine kinase genes identified in the human genome, 58 encode receptor tyrosine kinase proteins. Receptor tyrosine kinases have been shown not...
    28 KB (3,078 words) - 07:46, 3 June 2024
  • A protein kinase inhibitor (PKI) is a type of enzyme inhibitor that blocks the action of one or more protein kinases. Protein kinases are enzymes that...
    23 KB (750 words) - 23:26, 13 August 2024
  • Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a dual-specificity kinase enzyme which phosphorylates mitogen-activated protein kinase (MAPK)...
    3 KB (296 words) - 17:06, 14 September 2023
  • Thumbnail for Kinase
    ability to bind other molecules. Therefore, kinases are critical in metabolism, cell signalling, protein regulation, cellular transport, secretory processes...
    34 KB (3,807 words) - 19:38, 18 August 2024
  • Thumbnail for Rho-associated protein kinase
    Rho-associated protein kinase (ROCK) is a kinase belonging to the AGC (PKA/ PKG/PKC) family of serine-threonine specific protein kinases. It is involved...
    19 KB (2,170 words) - 06:41, 27 May 2024
  • biology, extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that...
    11 KB (1,128 words) - 19:03, 18 September 2023
  • CaMK or CCaMK, is an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes. CAMKs are activated by increases in the concentration...
    8 KB (886 words) - 12:46, 31 January 2024
  • Thumbnail for Myotonin-protein kinase
    Myotonin-protein kinase (MT-PK) also known as myotonic dystrophy protein kinase (MDPK) or dystrophia myotonica protein kinase (DMPK) is an enzyme that...
    19 KB (2,426 words) - 16:47, 30 March 2024
  • p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines...
    14 KB (1,385 words) - 10:32, 28 April 2024
  • Thumbnail for Cyclin-dependent kinase
    Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression...
    35 KB (3,829 words) - 14:24, 17 June 2024
  • Thumbnail for MTOR
    phosphatidylinositol 3-kinase-related kinase family of protein kinases. mTOR links with other proteins and serves as a core component of two distinct protein complexes...
    119 KB (12,658 words) - 19:25, 19 September 2024
  • Thumbnail for Protein kinase domain
    The protein kinase domain is a structurally conserved protein domain containing the catalytic function of protein kinases. Protein kinases are a group...
    17 KB (1,566 words) - 18:56, 22 September 2024
  • Thumbnail for C-Jun N-terminal kinases
    transcriptional activation domain. They belong to the mitogen-activated protein kinase family, and are responsive to stress stimuli, such as cytokines, ultraviolet...
    14 KB (1,626 words) - 20:50, 30 May 2024
  • Thumbnail for CGMP-dependent protein kinase
    cGMP-dependent protein kinase or protein kinase G (PKG) is a serine/threonine-specific protein kinase that is activated by cGMP. It phosphorylates a number of...
    8 KB (825 words) - 21:37, 20 April 2023
  • Thumbnail for Protein phosphorylation
    by a protein kinase by the addition of a covalently bound phosphate group. Phosphorylation alters the structural conformation of a protein, causing it...
    67 KB (7,955 words) - 20:50, 29 July 2024
  • Thumbnail for Tyrosin-protein kinase Lck
    Tyrosin-protein kinase Lck (or lymphocyte-specific protein tyrosine kinase) is a 56 kDa protein that is found inside lymphocytes and encoded in the human...
    36 KB (4,466 words) - 12:30, 11 May 2024
  • Thumbnail for Protein kinase R
    Protein kinase RNA-activated also known as protein kinase R (PKR), interferon-induced, double-stranded RNA-activated protein kinase, or eukaryotic translation...
    36 KB (4,105 words) - 14:32, 21 December 2023
  • Thumbnail for ATM serine/threonine kinase
    ATM serine/threonine kinase or Ataxia-telangiectasia mutated, symbol ATM, is a serine/threonine protein kinase that is recruited and activated by DNA...
    50 KB (5,684 words) - 10:12, 7 September 2024
  • Activated Protein (MAP) kinase kinase kinase (MAPKKK, MKKK, M3K, or, MAP3K) is a serine/threonine-specific protein kinase which acts upon MAP kinase kinase. Subsequently...
    11 KB (1,345 words) - 09:11, 2 January 2024
  • The IκB kinase enzyme complex is part of the upstream NF-κB signal transduction cascade. The IκBα (inhibitor of nuclear factor kappa B) protein inactivates...
    14 KB (1,447 words) - 09:31, 22 December 2023
  • Thumbnail for G protein-coupled receptor
    domain by protein kinases. Cyclic AMP-dependent protein kinases (protein kinase A) are activated by the signal chain coming from the G protein (that was activated...
    82 KB (9,384 words) - 16:34, 5 September 2024
  • Thumbnail for Proto-oncogene tyrosine-protein kinase Src
    tyrosine-protein kinase Src, also known as proto-oncogene c-Src, or simply c-Src (cellular Src; pronounced "sarc", as it is short for sarcoma), is a non-receptor...
    21 KB (2,648 words) - 12:12, 26 July 2024