• Thumbnail for Protein kinase B
    Protein kinase B (PKB), also known as Akt, is the collective name of a set of three serine/threonine-specific protein kinases that play key roles in multiple...
    35 KB (3,831 words) - 18:08, 20 August 2024
  • Thumbnail for Protein kinase A
    In cell biology, protein kinase A (PKA) is a family of serine-threonine kinase whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA...
    27 KB (2,665 words) - 17:03, 6 April 2024
  • Thumbnail for Serine/threonine-specific protein kinase
    A serine/threonine protein kinase (EC 2.7.11.-) is a kinase enzyme, in particular a protein kinase, that phosphorylates the OH group of the amino-acid...
    14 KB (1,210 words) - 13:35, 14 June 2024
  • In cell biology, protein kinase C, commonly abbreviated to PKC (EC 2.7.11.13), is a family of protein kinase enzymes that are involved in controlling...
    29 KB (2,856 words) - 15:13, 2 December 2024
  • Thumbnail for AMP-activated protein kinase
    5' AMP-activated protein kinase or AMPK or 5' adenosine monophosphate-activated protein kinase is an enzyme (EC 2.7.11.31) that plays a role in cellular...
    65 KB (7,149 words) - 03:42, 28 December 2024
  • A mitogen-activated protein kinase (MAPK or MAP kinase) is a type of serine/threonine-specific protein kinases involved in directing cellular responses...
    46 KB (5,510 words) - 21:54, 29 November 2024
  • biology, extracellular signal-regulated kinases (ERKs) or classical MAP kinases are widely expressed protein kinase intracellular signalling molecules that...
    11 KB (1,128 words) - 03:46, 28 September 2024
  • Thumbnail for CGMP-dependent protein kinase
    cGMP-dependent protein kinase or protein kinase G (PKG) is a serine/threonine-specific protein kinase that is activated by cGMP. It phosphorylates a number...
    8 KB (825 words) - 21:37, 20 April 2023
  • Thumbnail for Ca2+/calmodulin-dependent protein kinase II
    Ca2+ /calmodulin-dependent protein kinase II (CaM kinase II or CaMKII) is a serine/threonine-specific protein kinase that is regulated by the Ca2+ /calmodulin...
    29 KB (3,458 words) - 01:05, 2 November 2024
  • Mitogen-activated protein kinase kinase (also known as MAP2K, MEK, MAPKK) is a dual-specificity kinase enzyme which phosphorylates mitogen-activated protein kinase (MAPK)...
    3 KB (296 words) - 17:06, 14 September 2023
  • Thumbnail for C-Jun N-terminal kinases
    transcriptional activation domain. They belong to the mitogen-activated protein kinase family, and are responsive to stress stimuli, such as cytokines, ultraviolet...
    14 KB (1,626 words) - 20:50, 30 May 2024
  • Activated Protein (MAP) kinase kinase kinase (MAPKKK, MKKK, M3K, or, MAP3K) is a serine/threonine-specific protein kinase which acts upon MAP kinase kinase. Subsequently...
    11 KB (1,345 words) - 09:11, 2 January 2024
  • Thumbnail for Phosphoinositide-dependent kinase-1
    In the field of biochemistry, PDPK1 refers to the protein 3-phosphoinositide-dependent protein kinase-1, an enzyme which is encoded by the PDPK1 gene in...
    18 KB (2,127 words) - 19:11, 8 April 2024
  • Thumbnail for Tropomyosin receptor kinase B
    Tropomyosin receptor kinase B (TrkB), also known as tyrosine receptor kinase B, or BDNF/NT-3 growth factors receptor or neurotrophic tyrosine kinase, receptor,...
    39 KB (4,391 words) - 05:30, 23 October 2024
  • Thumbnail for Tyrosine kinase
    A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to the tyrosine residues of specific proteins inside a cell. It functions as...
    44 KB (5,283 words) - 12:50, 27 December 2024
  • Thumbnail for Proto-oncogene tyrosine-protein kinase Src
    Proto-oncogene tyrosine-protein kinase Src, also known as proto-oncogene c-Src, or simply c-Src (cellular Src; pronounced "sarc", as it is short for sarcoma)...
    21 KB (2,648 words) - 12:12, 26 July 2024
  • Thumbnail for ATM serine/threonine kinase
    ATM serine/threonine kinase or Ataxia-telangiectasia mutated, symbol ATM, is a serine/threonine protein kinase that is recruited and activated by DNA...
    50 KB (5,684 words) - 10:28, 19 November 2024
  • Thumbnail for MTOR
    phosphatidylinositol 3-kinase-related kinase family of protein kinases. mTOR links with other proteins and serves as a core component of two distinct protein complexes...
    119 KB (12,661 words) - 15:12, 8 November 2024
  • CaMK or CCaMK, is an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes. CAMKs are activated by increases in the concentration...
    8 KB (886 words) - 12:46, 31 January 2024
  • Thumbnail for Cyclin-dependent kinase
    Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression...
    35 KB (3,830 words) - 11:41, 4 December 2024
  • Thumbnail for Protein phosphorylation
    by a protein kinase by the addition of a covalently bound phosphate group. Phosphorylation alters the structural conformation of a protein, causing it...
    67 KB (7,955 words) - 20:50, 29 July 2024
  • Thumbnail for BRAF (gene)
    BRAF (gene) (redirect from B-raf 1)
    the protein is more formally known as serine/threonine-protein kinase B-Raf. The B-Raf protein is involved in sending signals inside cells which are involved...
    48 KB (5,285 words) - 16:26, 21 August 2024
  • Thumbnail for Bruton's tyrosine kinase
    Bruton's tyrosine kinase (abbreviated Btk or BTK), also known as tyrosine-protein kinase BTK, is a tyrosine kinase that is encoded by the BTK gene in humans...
    27 KB (2,841 words) - 20:02, 9 December 2024
  • Thumbnail for Cyclin-dependent kinase 4
    Cyclin-dependent kinase 4 (CDK4), also known as cell division protein kinase 4, is an enzyme that is encoded by the CDK4 gene in humans. CDK4 is a member...
    30 KB (3,555 words) - 06:57, 30 December 2024
  • p38 mitogen-activated protein kinases are a class of mitogen-activated protein kinases (MAPKs) that are responsive to stress stimuli, such as cytokines...
    14 KB (1,385 words) - 10:32, 28 April 2024
  • response to extracellular signals. Key proteins involved are PI3K (phosphatidylinositol 3-kinase) and Akt (protein kinase B). Initial stimulation by one of the...
    36 KB (4,072 words) - 08:10, 29 October 2024
  • Thumbnail for Receptor tyrosine kinase
    unique tyrosine kinase genes identified in the human genome, 58 encode receptor tyrosine kinase proteins. Receptor tyrosine kinases have been shown not...
    28 KB (3,078 words) - 12:51, 27 December 2024
  • A protein kinase inhibitor (PKI) is a type of enzyme inhibitor that blocks the action of one or more protein kinases. Protein kinases are enzymes that...
    23 KB (750 words) - 23:26, 13 August 2024
  • Thumbnail for RAF kinase
    RAF kinases are a family of three serine/threonine-specific protein kinases that are related to retroviral oncogenes. The mouse sarcoma virus 3611 contains...
    5 KB (556 words) - 08:06, 3 June 2024
  • Thumbnail for Rho-associated protein kinase
    Rho-associated protein kinase or Rho-associated coiled-coil kinase (ROCK) is a kinase belonging to the AGC (PKA/ PKG/PKC) family of serine-threonine specific...
    19 KB (2,173 words) - 17:14, 20 December 2024