• 2,5-Diketopiperazine is an organic compound with the formula (NHCH2C(O))2. The compound features a six-membered ring containing two amide groups at opposite...
    22 KB (2,289 words) - 13:18, 29 June 2024
  • Thumbnail for Diketopiperazine
    ethylenediamine. 2,5-Diketopiperazines are cyclodipeptides often obtainable via condensation of two α-amino acids. 2,6-Diketopiperazines may be viewed as...
    4 KB (413 words) - 03:16, 28 November 2023
  • Thumbnail for Tadalafil
    Tadalafil (category Diketopiperazines)
    body of inhibiting PDE11 are not known. Tadalafil is an annulated 2,5-diketopiperazine. It is also a 1,2,3,4-tetrahydro-β-carboline. Tadalafil can be synthesized...
    35 KB (3,239 words) - 13:23, 19 September 2024
  • Thumbnail for Glycylglycine
    synthesized by Emil Fischer and Ernest Fourneau in 1901 by boiling 2,5-diketopiperazine (glycine anhydride) with hydrochloric acid. Shaking with alkali and...
    6 KB (393 words) - 17:18, 18 June 2024
  • Thumbnail for Verruculogen
    Verruculogen (category Diketopiperazines)
    strains of aspergillus that belongs to a class of naturally occurring 2,5-diketopiperazines. It is an annulated analogue of cyclo(L-Trp-L-Pro) which belongs...
    3 KB (198 words) - 14:34, 25 September 2023
  • Thumbnail for Brevianamide F
    Brevianamide F (category Diketopiperazines)
    cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. It is the simplest member and the biosynthetic precursor of a large...
    6 KB (560 words) - 16:41, 4 January 2024
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    pp. 225–256. ISBN 978-3-527-33107-9. Borthwick AD (July 2012). "2,5-Diketopiperazines: synthesis, reactions, medicinal chemistry, and bioactive natural...
    7 KB (749 words) - 14:33, 28 May 2024
  • Thumbnail for Cyclic peptide
    residue to the alpha amine of another). The smallest such species are 2,5-diketopiperazines, being derived from the cyclisation of a dipeptide. Cyclic isopeptides...
    9 KB (981 words) - 18:07, 25 September 2024
  • Thumbnail for Glycine
    2CONHCH 2COO− + H2O Pyrolysis of glycine or glycylglycine gives 2,5-diketopiperazine, the cyclic diamide. It forms esters with alcohols. They are often...
    38 KB (3,445 words) - 15:52, 11 September 2024
  • Thumbnail for Spirotryprostatin A
    Spirotryprostatin A (category Diketopiperazines)
    Spirotryprostatin A is an indolic alkaloid from the 2,5-Diketopiperazine class of natural products found in the Aspergillus fumigatus fungus. Spirotryprostatin...
    3 KB (176 words) - 16:58, 16 July 2021
  • Partisi, Revolutionary Communard Party, Turkey Diketopiperazine, a class of organic compounds 2,5-Diketopiperazine, a specific form Duffin–Kemmer–Petiau algebra...
    917 bytes (136 words) - 11:23, 19 February 2024
  • Thumbnail for Cyclic glycine-proline
    Cyclic glycine-proline (category Diketopiperazines)
    small neuroactive peptide that belongs to a group of bioactive 2,5-diketopiperazines (2,5-DKPs) and is also known as cyclo-glycine-proline. cGP is a neutral...
    19 KB (1,936 words) - 22:05, 29 August 2024
  • Thumbnail for Rhodotorulic acid
    Rhodotorulic acid (category Diketopiperazines)
    Rhodotorulic acid is the smallest of the 2,5-diketopiperazine family of hydroxamate siderophores which are high-affinity chelating agents for ferric iron...
    3 KB (272 words) - 13:07, 5 August 2024
  • Thumbnail for Ethyl cyanohydroxyiminoacetate
    cyclization to oxazolinones or - especially for dipeptides - to 2,5-diketopiperazines. Subirós-Funosas, R.; Prohens, R.; Barbas, R.; El-Faham, A.; Albericio...
    9 KB (898 words) - 18:07, 30 July 2024
  • Thumbnail for Barettin
    Barettin (category Diketopiperazines)
    tryptophan linked by two peptide bonds to an arginine residue, forming a 2,5-diketopiperazine nucleus. It is a cyclic dipeptide. Barettin is the major compound...
    5 KB (403 words) - 01:59, 16 April 2024
  • Thumbnail for Stephacidin
    Stephacidin (category Diketopiperazines)
    of naturally occurring 2,5-diketopiperazines. This unusual family of fungal metabolites are complex bridged 2,5-diketopiperazine alkaloids that possess...
    5 KB (516 words) - 01:26, 11 October 2021
  • dipeptide derived from glycine and (R-)valine is converted into a 2,5-Diketopiperazine (a cyclic dipeptide). Double O-methylation gives the bis-lactim....
    4 KB (444 words) - 19:38, 27 October 2022
  • Thumbnail for Retosiban
    Retosiban (category Diketopiperazines)
    series of 2,5 diketopiperazine oxytocin antagonists the (3S, 6S, 7S) isomer is >500 less active than the (3R, 6R, 7R)-isomer. In addition to the 2,5 diketopiperazine...
    10 KB (1,099 words) - 16:40, 19 December 2023
  • Thumbnail for Roquefortine C
    Roquefortine C (category Diketopiperazines)
    C is a mycotoxin that belongs to a class of naturally occurring 2,5-diketopiperazines produced by various fungi, particularly species from the genus Penicillium...
    7 KB (566 words) - 20:24, 29 January 2023
  • acid Dihydrouracil, an intermediate in the catabolism of uracil 2,5-Diketopiperazine Ethyl diazoacetate, a reagent used in organic chemistry Muscimol...
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  • Thumbnail for Gliotoxin
    Gliotoxin (category Diketopiperazines)
    sulfur-containing mycotoxin that belongs to a class of naturally occurring 2,5-diketopiperazines produced by several species of fungi, especially those of marine...
    31 KB (3,171 words) - 18:28, 7 June 2024
  • Thumbnail for Plasmopara viticola
    (October 2014). "Lysobacter capsici AZ78 produces cyclo(L-Pro-L-Tyr), a 2,5-diketopiperazine with toxic activity against sporangia of Phytophthora infestans and...
    28 KB (3,434 words) - 22:18, 12 September 2024
  • Thumbnail for Piscarinine
    Piscarinine (category Diketopiperazines)
    piscarium Westling that belong to a class of naturally occurring 2,5-diketopiperazines. The cytotoxic dehydroproline tryptophan derivatives piscarinines...
    2 KB (159 words) - 00:28, 7 April 2022
  • Thumbnail for Erlenmeyer–Plöchl azlactone and amino-acid synthesis
    been employed as the enolate-forming component of the condensation. 2,5-Diketopiperazine can be used as a methylene component as well; its condensation products...
    5 KB (578 words) - 12:26, 26 March 2023
  • Fellutanine (category Diketopiperazines)
    diketopiperazine alkaloids isolated from the cultures of Penicillium fellutanum, that belongs to a class of naturally occurring 2,5-diketopiperazines...
    2 KB (247 words) - 15:54, 17 April 2024
  • Thumbnail for Fumitremorgin
    Fumitremorgin (category Diketopiperazines)
    and Penicillium, that belong to a class of naturally occurring 2,5-diketopiperazines. Biosynthesis pathway of fumitremorgin pathway involves several...
    3 KB (332 words) - 20:10, 24 September 2024
  • induce the formation of scabs on potato tubers. They are classed as 2,5-Diketopiperazines, with the most abundant having the chemical formula C22H22N406....
    29 KB (3,294 words) - 20:03, 19 September 2024
  • Thumbnail for Spirotryprostatin B
    Spirotryprostatin B (category Diketopiperazines)
    fumigatus fungus that belongs to a class of naturally occurring 2,5-diketopiperazines.[1] Spirotryprostatin B and several other indolic alkaloids (including...
    10 KB (871 words) - 01:03, 20 June 2023
  • Thumbnail for Bicyclomycin
    Bicyclomycin (category Diketopiperazines)
    aizumenses in 1972. It belongs to a class of naturally occurring 2,5-diketopiperazines, that are among the most numerous of all the naturally occurring...
    9 KB (839 words) - 21:35, 21 November 2023
  • Thumbnail for Rugulosuvine
    Rugulosuvine (category Diketopiperazines)
    naturally occurring 2,5-diketopiperazines. Kozlovskiĭ AG, Adanin VM, Dahse HM, Grafe U (2001). "[Rugulosuvines A and B--diketopiperazine alkaloids from Penicillium...
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