chemists as chiral or handed molecules. Each twin is called an enantiomer. Drugs that exhibit handedness are referred to as chiral drugs. Chiral drugs that are...

Chirality /kaɪˈrælɪtiː/ is a property of asymmetry important in several branches of science. The word chirality is derived from the Greek χείρ (kheir)...

improved therapeutic efficacy. The switch from a racemic drug to an enantiopure drug is called a chiral switch. In many cases, the enantiomers have distinct...

In chemistry, a molecule or ion is called chiral (/ˈkaɪrəl/) if it cannot be superposed on its mirror image by any combination of rotations, translations...

enantiomers from racemate drugs. For example, levofloxacin is a chiral switch of racemic ofloxacin. The essential principle of a chiral switch is that there...

one of many chiral forms, so different enantiomers of a chiral drug molecule bind differently (or not at all) to target receptors. Chirality can be observed...

enantioselective analysis. Chiral analysis includes all analytical procedures focused on the characterization of the properties of chiral drugs. Chiral analysis is usually...

optically active compounds, including drugs. Another term with the same meaning is optical resolution. The use of chiral resolution to obtain enantiomerically...

of drugs (oxazepam, lorazepam, temazepam), thalidomide, and tiaprofenic acid. A brief list of select pharmaceutical drugs that go through chiral inversion...

Chiral column chromatography is a variant of column chromatography that is employed for the separation of chiral compounds, i.e. enantiomers, in mixtures...

In stereochemistry, a chiral auxiliary is a stereogenic group or unit that is temporarily incorporated into an organic compound in order to control the...

common from around 1960, distinguishes these drugs from corticosteroids, another class of anti-inflammatory drugs, which during the 1950s had acquired a bad...

PMID 10189176. S2CID 38496241. Lin GQ, You QD, Cheng JF, eds. (August 8, 2011). Chiral Drugs: Chemistry and Biological Action. John Wiley & Sons. p. 88. ISBN 9781118075630...

reaction (or reaction sequence) in which one or more new elements of chirality are formed in a substrate molecule and which produces the stereoisomeric...

Limited) Ibuprofen Ketoprofen Thalidomide Chirality Chiral drugs Chiral inversion "FDA-sourced list of all drugs with black box warnings (Use Download Full...

Chemical structures of the catecholamines Sympathomimetic drugs (also known as adrenergic drugs and adrenergic amines) are stimulant compounds which mimic...

is one that has equal amounts of left- and right-handed enantiomers of a chiral molecule or salt. Racemic mixtures are rare in nature, but many compounds...

The chiral pool is a "collection of abundant enantiopure building blocks provided by nature" used in synthesis. In other words, a chiral pool would be...

Inc. p. 172. Nguyen, Lien Ai; He, Hua; Pham-Huy, Chuong (2016-11-20). "Chiral Drugs: An Overview". International Journal of Biomedical Science. 2 (2): 85–100...

Skálová L, Szotáková B (December 2004). "Chiral inversion of drugs: coincidence or principle?". Current Drug Metabolism. 5 (6): 517–533. doi:10.2174/1389200043335360...

doi:10.1016/0006-2952(88)90762-9. PMID 3276314. Simonyi M (1984). "On chiral drug action". Medicinal Research Reviews. 4 (3): 359–413. doi:10.1002/med...

tissues and fluids. 50% is excreted unchanged in urine. Chiral drugs Chirality Enantiopure drug Stereochemistry Hamilton R (2015). Tarascon Pocket Pharmacopoeia...

classes of drugs are suspected to be particularly problematic because of their chemistry. Some of these include chiral drugs, poorly absorbed drugs, and cytotoxic...

unaffected. Chiral switch Enantiopure drug Chirality Eudysmic ratio Ibuprofen Hardikar MS (September 2008). "Chiral non-steroidal anti-inflammatory drugs--a review"...

OCLC 1097808137. Agranat I, Caner H (July 1999). "Intellectual property and chirality of drugs". Drug Discovery Today. 4 (7): 313–321. doi:10.1016/s1359-6446(99)01363-x...

and the way a drug works depends on what kind of enantiomer it is. Many drugs are chiral and it is important that the shape of the drug matches the shape...

patient. Many drugs are available as both a racemic mixture (equal amounts of both chiralities) and an enantiopure drug (only one chirality). Depending...

failure. A number of drug interactions can occur between MDMA and other drugs, including serotonergic drugs. MDMA also interacts with drugs which inhibit CYP450...

WHO/MVP/EMP/IAU/2019.06. License: CC BY-NC-SA 3.0 IGO. Lin GQ, You QD, Cheng JF (2011). Chiral Drugs: Chemistry and Biological Action. John Wiley & Sons. p. 120. ISBN 9781118075630...

orphenadrine and other drugs used as NSAIDs or adjuvant, atypical or potentiators for pain treatment. Trials are going on for using this drug along with ibuprofen...