• Thumbnail for Monoamine oxidase A
    Monoamine oxidase A, also known as MAO-A, is an enzyme (E.C. 1.4.3.4) that in humans is encoded by the MAOA gene. This gene is one of two neighboring gene...
    40 KB (4,635 words) - 13:34, 21 September 2024
  • Thumbnail for Monoamine oxidase inhibitor
    Monoamine oxidase inhibitors (MAOIs) are a class of drugs that inhibit the activity of one or both monoamine oxidase enzymes: monoamine oxidase A (MAO-A)...
    37 KB (4,019 words) - 14:53, 25 September 2024
  • Thumbnail for Monoamine oxidase
    Monoamine oxidases (MAO) (EC 1.4.3.4) are a family of enzymes that catalyze the oxidation of monoamines, employing oxygen to clip off their amine group...
    36 KB (3,853 words) - 23:04, 8 September 2024
  • Thumbnail for Monoamine oxidase B
    Monoamine oxidase B, also known as MAO-B, is an enzyme that in humans is encoded by the MAOB gene. The protein encoded by this gene belongs to the flavin...
    34 KB (4,091 words) - 20:20, 23 May 2024
  • Thumbnail for Monoamine neurotransmitter
    Monoamine reuptake inhibitor Monoamine receptor Monoamine oxidase Monoamine transporter Monoamine Hypothesis Biogenic amine Trace amine Monoamine nuclei...
    7 KB (1,409 words) - 21:17, 11 March 2024
  • Thumbnail for Brunner syndrome
    diarrhea Brunner syndrome is caused by a monoamine oxidase A (MAOA) deficiency, which leads to an excess of monoamines in the brain, such as serotonin, dopamine...
    8 KB (845 words) - 19:42, 27 September 2024
  • Thumbnail for Antidepressant
    of atoms. Monoamine oxidase inhibitors (MAOIs) are chemicals that inhibit the activity of the monoamine oxidase enzyme family. They have a long history...
    186 KB (20,305 words) - 20:13, 27 September 2024
  • of a hydrogen atom, oxygen is reduced to water (H2O) or hydrogen peroxide (H2O2). Some oxidation reactions, such as those involving monoamine oxidase or...
    3 KB (333 words) - 13:46, 25 December 2023
  • generations of antidepressants. They have a much lower adverse effect profile than older antidepressants like monoamine oxidase inhibitors (MAOIs) and tricyclic...
    46 KB (4,437 words) - 19:23, 17 September 2024
  • mood. An offshoot of the monoamine hypothesis suggests that monoamine oxidase A (MAO-A), an enzyme which metabolizes monoamines, may be overly active in...
    124 KB (14,600 words) - 01:19, 13 September 2024
  • Thumbnail for Serotonin syndrome
    inhibitor (SSRI), serotonin norepinephrine reuptake inhibitor (SNRI), monoamine oxidase inhibitor (MAOI), tricyclic antidepressants (TCAs), amphetamines,...
    53 KB (5,340 words) - 23:51, 19 September 2024
  • Thumbnail for Phenethylamine
    Phenethylamine (category Drugs that are a physiological drug)
    phenethylamine, a significant amount is metabolized in the small intestine by monoamine oxidase B (MAO-B) and then aldehyde dehydrogenase (ALDH), which converts it...
    46 KB (4,509 words) - 20:09, 6 September 2024
  • Thumbnail for Harmala alkaloid
    Harmala alkaloid (category Monoamine oxidase inhibitors)
    Harmala alkaloids are several alkaloids that act as monoamine oxidase inhibitors (MAOIs). These alkaloids are found in the seeds of Peganum harmala (also...
    14 KB (1,526 words) - 03:35, 8 September 2024
  • Thumbnail for N,N-Dimethyltryptamine
    N,N-Dimethyltryptamine (category Drugs that are a physiological drug)
    Effects can last three hours or more when orally ingested along with a monoamine oxidase inhibitor (MAOI), such as the ayahuasca brew of many native Amazonian...
    144 KB (14,376 words) - 23:59, 24 September 2024
  • Thumbnail for Mirtazapine
    symptoms may occur with stopping. It is not recommended together with a monoamine oxidase inhibitor, although evidence supporting the danger of this combination...
    87 KB (7,810 words) - 18:36, 1 September 2024
  • Harmine (category Monoamine oxidase inhibitors)
    reversibly inhibits monoamine oxidase A (MAO-A), an enzyme which breaks down monoamines, making it a Reversible inhibitor of monoamine oxidase A (RIMA). Harmine...
    20 KB (2,016 words) - 19:39, 8 September 2024
  • noradrenergic and specific serotonergic antidepressants (NaSSAs). Monoamine oxidase inhibitors include Isocarboxazid (Marplan) Phenelzine (Nardil) Tranylcypromine...
    17 KB (1,478 words) - 23:23, 28 July 2024
  • Thumbnail for Selective serotonin reuptake inhibitor
    MAOIs disrupt monoamine oxidase, an enzyme which is needed to break down serotonin and other neurotransmitters. Without monoamine oxidase, the body is...
    141 KB (15,000 words) - 23:03, 26 September 2024
  • Thumbnail for Sertraline
    with a mildly elevated rate of suicidal thoughts in people under the age of 25 years old. It should not be used together with monoamine oxidase inhibitors...
    102 KB (10,567 words) - 23:29, 20 September 2024
  • Thumbnail for Moclobemide
    Moclobemide (category Monoamine oxidase inhibitors)
    Aurorix, Clobemix, Depnil and Manerix among others, is a reversible inhibitor of monoamine oxidase A (RIMA) drug primarily used to treat depression and social...
    83 KB (9,078 words) - 17:51, 7 September 2024
  • Thumbnail for 5-Hydroxyindoleacetaldehyde
    the monoamine neurotransmitter serotonin (5-hydroxytryptamine; 5-HT). 5-HIAL is formed from serotonin by oxidative deamination via monoamine oxidase (MAO)...
    7 KB (621 words) - 00:18, 9 September 2024
  • acute inhibition of both monoamine oxidase A and B reduce anxiety or freezing behavior. However, inhibition of monoamine oxidase A or B alone failed to do...
    12 KB (1,502 words) - 16:09, 9 April 2024
  • Thumbnail for Tranylcypromine
    Tranylcypromine (category Monoamine oxidase inhibitors)
    is a monoamine oxidase inhibitor (MAOI). More specifically, tranylcypromine acts as nonselective and irreversible inhibitor of the enzyme monoamine oxidase...
    27 KB (2,535 words) - 06:17, 2 September 2024
  • Thumbnail for SU-11739
    SU-11739 (category Monoamine oxidase inhibitors)
    experimental monoamine oxidase inhibitor (MAOI) that was never marketed. It is a dual or non-selective irreversible monoamine oxidase A (MAO-A) and monoamine oxidase...
    6 KB (505 words) - 15:27, 19 September 2024
  • Thumbnail for Selegiline
    Selegiline (category Monoamine oxidase inhibitors)
    liability and is not a controlled substance. Selegiline acts as a monoamine oxidase inhibitor (MAOI) and thereby increases levels of monoamine neurotransmitters...
    206 KB (20,032 words) - 18:37, 27 September 2024
  • Thumbnail for Ayahuasca
    harmine, harmaline and tetrahydroharmine (THH), which can act as monoamine oxidase inhibitors (MAOi). This halts the liver and gastrointestinal metabolism...
    91 KB (9,997 words) - 16:45, 24 September 2024
  • Thumbnail for Hydrazine (antidepressant)
    The hydrazine antidepressants are a group of non-selective, irreversible monoamine oxidase inhibitors (MAOIs) which were discovered and initially marketed...
    2 KB (162 words) - 17:14, 22 September 2024
  • Thumbnail for 9-Methyl-β-carboline
    9-Methyl-β-carboline (category Monoamine oxidase inhibitors)
    an animal model of Parkinsonism. 9-Me-BC is a known inhibitor of monoamine oxidase A and monoamine oxidase B, and has been proposed for further investigation...
    7 KB (553 words) - 19:38, 8 September 2024
  • Thumbnail for Bupropion
    tolerance. Caution should be observed when combining bupropion with a monoamine oxidase inhibitor (MAOI), as it may result in hypertensive crisis. The mechanism...
    136 KB (12,519 words) - 04:24, 22 September 2024
  • Thumbnail for Rasagiline
    Rasagiline (category Monoamine oxidase inhibitors)
    enzyme monoamine oxidase (MAO) and hence is a monoamine oxidase inhibitor (MAOI). More specifically, it is a selective inhibitor of monoamine oxidase B (MAO-B)...
    88 KB (8,602 words) - 23:49, 19 September 2024