Myostatin (also known as growth differentiation factor 8, abbreviated GDF8) is a protein that in humans is encoded by the MSTN gene. Myostatin is a myokine...
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Myostatin inhibitors are a class of drugs that work by blocking the effects of myostatin, which inhibits muscle growth. In animal models and limited human...
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Myostatin-related muscle hypertrophy is a rare genetic condition characterized by reduced body fat and increased skeletal muscle size. Affected individuals...
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natural mutation in the myostatin gene which codes for the protein, myostatin ("myo" meaning muscle and "statin" meaning stop). Myostatin is a protein that...
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known mutations that limits and reduces the activity of the myostatin protein. Normally, myostatin limits the number of muscle fibers present at birth, and...
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identified a natural variant of the myostatin gene found in Limousins which has a significant influence on them. The myostatin gene is found in all mammals and...
86 KB (10,454 words) - 13:47, 10 January 2024
Piedmontese cattle carry a unique gene mutation identified as an inactive myostatin allele that causes hypertrophic muscle growth, or double muscling. Purebred...
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PMID 23995658. Lee SJ, Gharbi A, Shin JE, Jung ID, Park YM (March 2021). "Myostatin inhibitor YK11 as a preventative health supplement for bacterial sepsis"...
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naturally occurring gene identified as the myostatin allele mutation, or inactive myostatin gene. Myostatin prohibits muscle growth whereas an inactive...
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amount of myostatin portray deficiency in muscle development and increase of fat; on the other hand, smaller than normal amounts of myostatin greatly increase...
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second leading cause of mortality in Whippets. A 2007 study identified a myostatin mutation particular to Whippets that is significantly associated with...
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Stamulumab (category Myostatin inhibitors)
Stamulumab (MYO-029) is an experimental myostatin inhibiting drug developed by Wyeth Pharmaceuticals for the treatment of muscular dystrophy (MD). Stamulumab...
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Gene doping (section Myostatin)
small interfering RNA. Myostatin is a protein responsible for inhibiting muscle differentiation and growth. Removing the myostatin gene or otherwise limiting...
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; McPherron, Alexandra C. (October 2011). "Expression and Function of Myostatin in Obesity, Diabetes, and Exercise Adaptation". Medicine and Science in...
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binds to myostatin, it lowers the amount of myostatin that can bind to the native receptor in the membrane (ActRIIB), preventing myostatin from delivering...
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receptors regulate muscle growth. Myostatin, a TGF-beta superfamily member, is a negative regulator of muscle growth. Myostatin binds to ACVR2B and to a lesser...
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(Drm) LTBP1 Noggin TGIF Thrombospondin 1 (THBS1) Tomoregulin 1 Antibodies: Stamulumab (against myostatin) TRC105 (against endoglin) Others: Endoglin...
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Follistatin (category Myostatin inhibitors)
its role in regulation of muscle growth in mice, as an antagonist to myostatin (also known as GDF-8, a TGF superfamily member) which inhibits excessive...
19 KB (2,169 words) - 20:45, 12 May 2024
(Drm) LTBP1 Noggin TGIF Thrombospondin 1 (THBS1) Tomoregulin 1 Antibodies: Stamulumab (against myostatin) TRC105 (against endoglin) Others: Endoglin...
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Eddie Hall (category People with Myostatin-related muscle hypertrophy)
Edward Stephen Hall (born 15 January 1988) is a British media personality and retired strongman. He is best known for his world-record setting 500 kg (1...
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Apitegromab (category Myostatin inhibitors)
precursor to myostatin, which limits the size of skeletal muscle tissue, as well as inactive myostatin. It does not bind to active myostatin, activin A...
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to myostatin, a negative regulator of muscle growth, both structurally and phylogenetically. Though GDF11 is 90% structurally similar to myostatin, GDF11's...
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may refer to: Kocher–Debré–Semelaigne syndrome Adrenogenital syndrome Myostatin mutation resulting in hypertrophy and increased strength This disambiguation...
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to 1.2 the natural size with the same amount of food due to disabled myostatin, which inhibits muscle growth. Engineering first light of the Vera C....
297 KB (38,840 words) - 21:47, 4 June 2024
(Drm) LTBP1 Noggin TGIF Thrombospondin 1 (THBS1) Tomoregulin 1 Antibodies: Stamulumab (against myostatin) TRC105 (against endoglin) Others: Endoglin...
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follicle-stimulating hormone; it also has many other systemic effects. Myocytes use myostatin to tell each other to inhibit myogenesis. Melanocyte-inhibiting factor...
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Davis' law Follistatin Lean body mass Muscle atrophy Muscle dystrophy Myostatin Pseudoathletic appearance Pseudohypertrophy Baechle TR, Earle RW, eds...
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2013). "Hyperammonemia in cirrhosis induces transcriptional regulation of myostatin by an NF-κB–mediated mechanism". Proceedings of the National Academy of...
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the natural average size with the same amount of food due to disabled myostatin, which inhibits muscle growth. Creating genetically modified food is a...
144 KB (15,841 words) - 13:40, 27 May 2024