organometallic chemistry, organolithium reagents are chemical compounds that contain carbon–lithium (C–Li) bonds. These reagents are important in organic...

reagent deprotonating an organic molecule to create a new organometallic reagent. The most common classes of metallated compounds are organolithium reagents...

reaction scheme. In this aspect, they are similar to organolithium reagents. Grignard reagents are rarely isolated as solids. Instead, they are normally...

n-Butyllithium C4H9Li (abbreviated n-BuLi) is an organolithium reagent. It is widely used as a polymerization initiator in the production of elastomers...

solids.[citation needed] These reagents are useful because, unlike related Grignard reagents and organolithium reagents, they react with organic halides...

copper(I) halide and organolithium are combined. In conjunction with Lewis acidic additives such as boron trifluoride etherate, these reagents are used for conjugate...

This is a list of inorganic and organic reagents commonly used in chemistry. Reagents are "substances or compounds that are added to a system in order...

formula CH3CHLiCH2CH3, abbreviated sec-BuLi or s-BuLi. This chiral organolithium reagent is used as a source of sec-butyl carbanion in organic synthesis...

through an intermediate hydrazone in the presence of 2 equivalents of organolithium reagent. The reaction was discovered by Robert H. Shapiro in 1967. The Shapiro...

Methyllithium is the simplest organolithium reagent, with the empirical formula CH3Li. This s-block organometallic compound adopts an oligomeric structure...

treatment of this species with an organometallic reagent such as a Grignard reagent or organolithium reagent. Nahm and Weinreb also reported the synthesis...

when the reagents are a weak acid and a weak base, a pH meter or a conductance meter are used. For very strong bases, such as organolithium reagent, metal...

substitution properties. Neophyl chloride is used to form a versatile organolithium reagent, neophyl lithium, by reaction with lithium. Neophyl chloride was...

allows for mono-addition of an organometallic reagent such as a Grignard reagent or organolithium reagent to an amide. Weinreb received his PhD for work...

usually with acid- or base-catalysis. Carbonation of a Grignard reagent and organolithium reagents: RLi + CO2 → RCO−2Li+ RCO−2Li+ + HCl → RCO2H + LiCl Halogenation...

intermediates in organic chemistry. In organic synthesis, organolithium reagents and Grignard reagents are commonly treated and referred to as "carbanions."...

Formylation of this structure was then achieved through using the organolithium reagent n-butyllithium followed by quenching with N,N-dimethylformamide...

the organolithium reagent (RLi > LiNR2) The Lewis basicity of the heteroatom substituent (N > O > S) When both the Lewis acidity of the organolithium compound...

Bodroux–Chichibabin aldehyde synthesis Fujimoto–Belleau reaction Organolithium reagents Sakurai reaction Indium-mediated allylation Alkynylation Smith,...

were first described by Charles R. Hauser in 1947. Compared with organolithium reagents, the magnesium compounds have more covalent, and therefore less...

Weinreb amide. When a carbon nucleophile – such as a Grignard or organolithium reagent – adds to a Weinreb amide, the metal is chelated by the carbonyl...

an imine With secondary amine gives an enamine With Grignard and organolithium reagents to give, after aqueous workup, a tertiary alcohol With an alcohols...

aggregates of organolithium species. Magnesium–halogen exchange Grignard reagents can be prepared by treating a preformed Grignard reagent with an organic...

use for atomic layer deposition of lithium compounds. Like many organolithium reagents, lithium bis(trimethylsilyl)amide can form aggregates in solution...

reactive than many other analogous organometallic reagents, such as Grignard and organolithium reagents. In 1848 Edward Frankland prepared the first organozinc...

of the cyanohydrin. Organometallic compounds, such as organolithium reagents, Grignard reagents, or acetylides, undergo nucleophilic addition reactions...

Carbolithiation is the addition of an organolithium reagent across a carbon-carbon pi-bond. The organolithium reagents used in this transformation can be...

2-methyl-3-butyn-2-ol from acetylene and acetone. Alkylation Methylation Organolithium reagent Organosodium chemistry Sonogashira coupling Glaser coupling Cadiot–Chodkiewicz...

fine chemicals, organolithium compounds function as strong bases and as reagents for the formation of carbon-carbon bonds. Organolithium compounds are prepared...

reaction, and Barbier reaction or reactions involving organolithium reagents and acetylides. These reagents are often used to perform nucleophilic additions...