Statins (or HMG-CoA reductase inhibitors) are a class of medications that lower cholesterol. They are prescribed typically to people who are at high risk...
134 KB (13,069 words) - 00:18, 30 December 2024
Atorvastatin (category Statins)
Atorvastatin is a statin medication used to prevent cardiovascular disease in those at high risk and to treat abnormal lipid levels. For the prevention...
100 KB (9,527 words) - 02:17, 17 January 2025
HMG-CoA (3-hydroxy-3-methylglutaryl-CoA) reductase inhibitors, called statins, was a breakthrough in the prevention of hypercholesterolemia and related...
23 KB (2,423 words) - 21:42, 17 January 2025
Generally it is used together with dietary changes and a statin. Alone, it is less preferred than a statin. It is taken by mouth. It is also available in the...
20 KB (1,872 words) - 08:05, 14 January 2025
Rosuvastatin (category Statins)
Rosuvastatin, sold under the brand name Crestor among others, is a statin medication, used to prevent cardiovascular disease in those at high risk and...
42 KB (3,484 words) - 07:45, 14 January 2025
Statin-associated autoimmune myopathy (SAAM), also known as anti-HMGCR myopathy, is a very rare form of muscle damage caused by the immune system in people...
12 KB (1,349 words) - 18:07, 19 March 2024
Coenzyme Q10 (section Statins)
an adjunctive therapy to reduce inflammation in periodontitis. Although statins may reduce CoQ10 in the blood it is unclear if they reduce CoQ10 in muscle...
49 KB (4,901 words) - 14:44, 7 January 2025
with a statin or statin with other lipid-lowering therapies in patients unable to reach LDL-C goals with the maximum tolerated dose of a statin; or alone...
18 KB (1,589 words) - 07:00, 29 December 2024
commonly used compared to statins because it treats a different type of cholesterol abnormality to statins. While statins have strong evidence for reducing...
26 KB (2,514 words) - 06:51, 30 December 2024
widely available cholesterol-lowering drugs known collectively as the statins, which help treat dyslipidemia. HMG-CoA reductase is anchored in the membrane...
34 KB (4,113 words) - 16:29, 29 July 2024
Hydroxymethylglutaryl-coenzyme A reductase inhibitors (HMG-CoA inhibitors or statins) Statins may sometimes cause myalgia and cramps among other possible side effects...
19 KB (2,017 words) - 15:04, 31 October 2024
the United States and other countries. Lovastatin and other prescription statin drugs inhibit cholesterol synthesis by blocking action of the enzyme HMG-CoA...
24 KB (2,917 words) - 03:29, 31 October 2024
Simvastatin (category Statins)
Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. It is used along with exercise, diet, and...
33 KB (3,277 words) - 16:06, 12 January 2025
low risk, the use of statin therapy depends on individual patient factors such as age, cholesterol levels, and risk factors. Statins are considered the...
31 KB (3,036 words) - 00:18, 13 December 2024
specifically PPARα, to decrease free fatty acid production. Statin drugs, especially the synthetic statins (atorvastatin and rosuvastatin) can decrease LDL levels...
47 KB (4,486 words) - 23:17, 16 January 2025
Cardiovascular agents (section Statins)
and beta-blockers. Antihyperlipidemic agents most often prescribed are statins, ezetimibe and fibrates. They either lower low-density lipoprotein cholesterol...
46 KB (5,038 words) - 04:38, 5 December 2024
Erythromycin (redirect from Erythro-Statin)
Erythromycin is an antibiotic used for the treatment of a number of bacterial infections. This includes respiratory tract infections, skin infections,...
42 KB (3,900 words) - 06:17, 16 January 2025
with a statin or statin with other lipid-lowering therapies in people unable to reach LDL-C goals with the maximum tolerated dose of a statin, or alone...
21 KB (1,744 words) - 14:15, 24 April 2024
begins with the mevalonate or HMG-CoA reductase pathway, the target of statin drugs, which encompasses the first 18 steps. This is followed by 19 additional...
80 KB (8,656 words) - 19:58, 29 December 2024
Pitavastatin (category Statins)
salt) is a member of the blood cholesterol lowering medication class of statins. Pitavastatin is an inhibitor of HMG-CoA reductase, the enzyme that catalyses...
11 KB (977 words) - 05:22, 23 December 2024
cholesterol levels in the blood. Statins are the typically used medications, in addition to healthy lifestyle interventions. Statins can reduce total cholesterol...
61 KB (6,215 words) - 19:38, 30 October 2024
acid/ezetimibe is indicated as an adjunct to diet and maximally tolerated statin therapy for the treatment of adults with heterozygous familial hypercholesterolemia...
10 KB (782 words) - 06:09, 16 July 2024
consisting of an extended release form of the lipid-lowering drug niacin and the statin drug simvastatin. It is used for the treatment of dyslipidemia. It was approved...
3 KB (183 words) - 19:28, 20 December 2023
Clarithromycin (section Statins)
sudden cardiac deaths in stable coronary heart disease patients not using statins. Clarithromycin has been known to cause jaundice, cirrhosis, and kidney...
29 KB (2,711 words) - 14:58, 12 January 2025
reduction than the statins, including statins alone at high dose (though not necessarily the combination of statins plus ezetimibe). Statins reduce high levels...
54 KB (6,076 words) - 20:15, 29 November 2024
relationship between fungi and cholesterol biosynthesis led to the development of statin drugs, which are some of the best-selling pharmaceuticals in history. Endo...
10 KB (862 words) - 08:11, 12 December 2024
(2015-10-13). "Clinical Effectiveness of Statin Therapy After Ischemic Stroke: Primary Results From the Statin Therapeutic Area of the Patient-Centered...
23 KB (2,333 words) - 09:54, 14 October 2024
the treatment of high cholesterol and high blood pressure. It contains a statin and a calcium channel blocker. Amlodipine/atorvastatin is marketed under...
4 KB (196 words) - 06:06, 17 June 2024
Maryanne Demasi (section Statin report)
challenges the scientific consensus on cholesterol, saturated fat and statins. She has argued that high-blood cholesterol and high saturated fat consumption...
19 KB (1,809 words) - 22:09, 12 September 2023
Pravastatin (category Statins)
Pravastatin, sold under the brand name Pravachol among others, is a statin medication, used for preventing cardiovascular disease in those at high risk...
14 KB (1,096 words) - 19:44, 21 September 2024