α-Galactosylceramide (α-GalCer, KRN7000) is a synthetic glycolipid derived from structure-activity relationship studies of galactosylceramides isolated...
4 KB (276 words) - 21:06, 7 June 2023
New components like α-galactosylceramide (α-GalCer) are also being researched to be used as nasal vaccines against influenza. Since α-GalCer induced immune...
29 KB (3,397 words) - 23:36, 24 August 2024
synthases responsible for the synthesis of glucuronosylceramide and α-galactosylceramide". Journal of Biological Chemistry. 295 (31): 10709–10725. doi:10...
49 KB (5,666 words) - 18:01, 30 October 2024
type I NKT cells recognize the marine sponge-derived glycolipid, α-galactosylceramide (α-GalCer). After the encounter with the antigen Type I NKT cells...
13 KB (1,585 words) - 05:15, 24 September 2023
Moriya Tsuji, Moriya (4 March 2002). "Natural Killer T Cell Ligand α-Galactosylceramide Enhances Protective Immunity Induced by Malaria Vaccines". Journal...
18 KB (2,096 words) - 22:09, 15 September 2024
Sonnenburg JL, Comstock LE, Bluestone JA, Fischbach MA. Production of α-galactosylceramide by a prominent member of the human gut microbiota. PLoS Biol. 2013...
9 KB (965 words) - 09:35, 25 April 2024
is also known as R3G1 Some of the known ligands for CD1d are: α-galactosylceramide (α-GalCer), a compound originally derived from the marine sponge Agelas...
15 KB (1,840 words) - 04:22, 15 October 2024
inversion of the glycosidic bond stereochemistry, changing from α →β. Synthesis of galactosylceramide, and glucosylceramide occurs on the lumenal surface of the...
6 KB (723 words) - 14:38, 6 December 2023
CD1 are not well characterized, but a synthetic glycolipid, alpha-galactosylceramide (α-GalCer), originally isolated from a compound found in a marine sponge...
15 KB (1,695 words) - 16:50, 21 April 2024
archae(bacteri)a. The best characterised O-mannosylated human protein is α-dystroglycan. O-Man sugars separate two domains of the protein, required to...
28 KB (3,150 words) - 21:50, 22 May 2024
University, 2016 SISACS Volunteer of the Year Award, 2016 Production of α-Galactosylceramide by a Prominent Member of the Human Gut Microbiota. L. C. Wieland...
4 KB (403 words) - 02:10, 30 June 2023
glycolipid antigens. The best known antigen of iNKT cells is alpha-galactosylceramide (αGalCer), which is a synthetic form of a chemical purified from the...
14 KB (1,648 words) - 09:58, 18 July 2023
sulfotransferase EC 2.8.2.10: Renilla-luciferin sulfotransferase EC 2.8.2.11: galactosylceramide sulfotransferase EC 2.8.2.12: deleted, identical to EC 2.8.2.8, [heparan...
215 KB (21,664 words) - 23:41, 8 May 2024
virotoxin model of HIV-1 enteropathy: involvement of GPR15/Bob and galactosylceramide in the cytopathic effects induced by HIV-1 gp120 in the HT-29-D4 intestinal...
13 KB (1,503 words) - 10:24, 23 March 2024
extremely compact and rigidly disulfide-linked molecules. Each saposin has an α-helical structure that is seen as being important for stimulation because...
14 KB (1,791 words) - 14:17, 9 October 2024