• Thumbnail for ADH1B
    Alcohol dehydrogenase 1B is an enzyme that in humans is encoded by the ADH1B gene. The protein encoded by this gene is a member of the alcohol dehydrogenase...
    13 KB (1,621 words) - 12:11, 24 January 2024
  • Thumbnail for Alcohol flush reaction
    acetaldehyde is worsened by another gene variant; in this case the allele ADH1B*2, which results in the alcohol dehydrogenase enzyme converting alcohol...
    15 KB (1,659 words) - 13:14, 30 August 2024
  • Thumbnail for Alcohol tolerance
    (PDF) on March 27, 2011. Eng, MY; Luczak, SE; Wall, TL (2007). "ALDH2, ADH1B, and ADH1C genotypes: A literature review". Alcohol Research & Health. 30...
    16 KB (1,602 words) - 19:34, 31 August 2024
  • Thumbnail for Alcoholism
    East. The alcohol dehydrogenase allele ADH1B*3 also causes a more rapid metabolism of alcohol. The allele ADH1B*3 is only found in some individuals of...
    148 KB (14,881 words) - 15:14, 3 September 2024
  • an allele of the gene coding for the enzyme alcohol dehydrogenase called ADH1B*2, which results in the alcohol dehydrogenase enzyme converting alcohol...
    25 KB (2,540 words) - 15:11, 20 August 2024
  • Thumbnail for Alcohol dehydrogenase
    have a major role in nitric oxide signaling. In humans, sequencing of the ADH1B gene (responsible for production of an alcohol dehydrogenase polypeptide)...
    50 KB (5,578 words) - 17:07, 15 June 2024
  • Thumbnail for Short-term effects of alcohol consumption
    disorders in Han Chinese and Japanese (due to presence of ADH1B*2 ) and in African (due to presence of ADH1B*3). On the other hand, presence of ALDH2*2 in East...
    48 KB (5,429 words) - 04:39, 26 July 2024
  • Thumbnail for Timeline of human evolution
    Xue-bin; Xiao, Chun-jie; Zhong, Hua; Ma, Run-lin Z; Su, Bing (2010). "The ADH1B Arg47His polymorphism in East Asian populations and expansion of rice domestication...
    87 KB (3,541 words) - 02:48, 4 September 2024
  • Thumbnail for Ethanol
    typically accompanied by another mutation in the alcohol dehydrogenase enzyme ADH1B in roughly 80 % of east Asians, which improves the catalytic efficiency...
    106 KB (10,639 words) - 07:07, 20 August 2024
  • Thumbnail for Ryukyuan people
    Koganebuchi; et al. (2016). "The allele frequency of ALDH2*Glu504Lys and ADH1B*Arg47His for the Ryukyu islanders and their history of expansion among East...
    95 KB (11,004 words) - 07:58, 5 September 2024
  • Thumbnail for Rhinitis
    a genetic variant in the gene that metabolizes ethanol to acetaldehyde, ADH1B, is associated with alcohol-induced rhinitis. It is suggested that this...
    34 KB (3,103 words) - 20:08, 11 April 2024
  • Thumbnail for Alcohol (drug)
    Goan YG, Chou SH, Wu IC, et al. (March 2008). "Carcinogenetic impact of ADH1B and ALDH2 genes on squamous cell carcinoma risk of the esophagus with regard...
    236 KB (24,287 words) - 10:59, 10 September 2024
  • problems with alcohol misuse. Having a particular genetic variant (A-allele of ADH1B rs1229984) is associated with non-drinking and lower alcohol consumption...
    73 KB (8,333 words) - 07:32, 9 September 2024
  • Academia Sinica found that genes in alcohol metabolism pathway, especially ADH1B and ALDH2, conferred the major genetic risk for alcohol dependence in Taiwanese...
    51 KB (4,263 words) - 16:11, 24 August 2024
  • of alleles, including variants of the EDAR, ADH1B, ABCC1, and ALDH2 genes. The East Asian types of ADH1B in particular are associated with rice domestication...
    47 KB (5,247 words) - 05:06, 28 July 2024
  • Thumbnail for Early modern human
    related to agriculture and animal domestication including East Asian types of ADH1B associated with rice domestication, or lactase persistence, are due to recent...
    115 KB (12,513 words) - 08:20, 4 September 2024
  • Thumbnail for Early human migrations
    pressures. This concerns the genes EDAR, ADH1B, ABCC1, and ALDH2 in particular. The East Asian types of ADH1B are associated with rice domestication and...
    112 KB (11,948 words) - 23:52, 21 August 2024
  • NAD+-dependent alcohol dehydrogenase (ADH) class I enzymes (i.e. ADH1A, ADH1B, and ADH1C), and then metabolize acetaldehyde primarily by NAD2-dependent...
    16 KB (2,276 words) - 11:24, 25 April 2024
  • Thumbnail for Pharmacology of ethanol
    alcohol dehydrogenase, particularly the IB (class I), beta polypeptide (ADH1B, EC 1.1.1.1) enzyme. The reaction uses NAD+ to convert the ethanol into...
    96 KB (10,550 words) - 10:57, 20 July 2024
  • related to agriculture and animal domestication include East Asian types of ADH1B associated with rice domestication, and lactase persistence. As Europeans...
    102 KB (11,865 words) - 00:53, 9 August 2024
  • Luczak SE, Glatt SJ, Wall TL (July 2006). "Meta-analyses of ALDH2 and ADH1B with alcohol dependence in Asians". Psychological Bulletin. 132 (4): 607–21...
    83 KB (7,999 words) - 11:38, 1 September 2024
  • Thumbnail for Alcohol abuse
    multiple genes may be potentially implicated, alcohol dehydrogenase 1B (ADH1B) and aldehyde dehydrogenase 2 (ALDH2; mitochondrial aldehyde dehydrogenase)...
    78 KB (8,762 words) - 02:47, 24 August 2024
  • HGNC:20822 Q9HBW9 349 ADGRV1 HGNC:17416 Q8WXG9 350 ADH1A HGNC:249 P07327 351 ADH1B HGNC:250 P00325 352 ADH1C HGNC:251 P00326 353 ADH4 HGNC:252 P08319 354 ADH5...
    277 KB (17 words) - 23:17, 27 April 2024
  • Thumbnail for Alcohol and cancer
    which is a byproduct that can be excreted through the liver. Those with ADH1B*1 have higher rates of conversion of ethanol into acetaldehyde while, people...
    123 KB (13,421 words) - 14:50, 1 August 2024
  • et al. (September 2003). "Allelic variation at alcohol metabolism genes ( ADH1B, ADH1C, ALDH2) and alcohol dependence in an American Indian population"...
    94 KB (10,799 words) - 18:42, 11 September 2024
  • Thumbnail for ADH1A
    ALCOHOL DEHYDROGENASE (ADH1A) 1hsz: HUMAN BETA-1 ALCOHOL DEHYDROGENASE (ADH1B*1) 1ht0: HUMAN GAMMA-2 ALCOHOL DEHYDROGENSE 1htb: CRYSTALLIZATION OF HUMAN...
    6 KB (841 words) - 14:27, 24 January 2024
  • Thumbnail for ADH1C
    ALCOHOL DEHYDROGENASE (ADH1A) 1hsz: HUMAN BETA-1 ALCOHOL DEHYDROGENASE (ADH1B*1) 1ht0: HUMAN GAMMA-2 ALCOHOL DEHYDROGENSE 1htb: CRYSTALLIZATION OF HUMAN...
    8 KB (950 words) - 21:23, 1 September 2023
  • PMID 10923994. Cited by 275 as of October 18, 2019. Bierut LJ et al. (2012) "ADH1B is associated with alcohol dependence and alcohol consumption in populations...
    34 KB (2,363 words) - 16:13, 16 June 2024
  • Thumbnail for CYP2A7
    Mohelnikova-Duchonova B, Vrana D, Holcatova I, et al. (2010). "CYP2A13, ADH1B, and ADH1C gene polymorphisms and pancreatic cancer risk". Pancreas. 39...
    9 KB (1,076 words) - 18:28, 6 November 2023