Transcriptional regulator ATRX also known as ATP-dependent helicase ATRX, X-linked helicase II, or X-linked nuclear protein (XNP) is a protein that in...

a P-loop, or Walker motif-containing family. The ATRX gene encodes the ATP-dependent helicase, ATRX (also known as XH2 and XNP) of the SNF2 subgroup family...

synaptophysin. Genetic testing thereof typically shows altered MEN1 and DAXX/ATRX. The new 2019 WHO classification and grading criteria for neuroendocrine...

Alpha-thalassemia mental retardation syndrome (ATRX), also called alpha-thalassemia X-linked intellectual disability syndrome, nondeletion type or ATR-X...

PanNet. Other genes that are frequently mutated include DAXX, mTOR, and ATRX. The symptoms of pancreatic adenocarcinoma do not usually appear in the disease's...

(PRMT). ATRX-syndrome (α-thalassemia X-linked mental retardation) and α-thalassemia myelodysplasia syndrome are caused by mutations in ATRX, a SNF2-related...

Fernandes AD, Tremblay DC, Seah C, Bérubé NG (2008). "The SWI/SNF protein ATRX co-regulates pseudoautosomal genes that have translocated to autosomes in...

immunohistochemistry for the presence of R132H-mutant IDH1 and loss of nuclear ATRX. In patients aged >55 years with a histologically typical glioblastoma, without...

However, mutations have also been found in FMR1, FLNA, UPF3B, CASK, MECP2 and ATRX genes. Mutations on these different genes lead to the different types of...

1p and 19q indicates the tumor is an oligodendroglioma Loss of TP53 and ATRX characterizes astrocytomas Genes EGFR, TERT, and PTEN, are commonly altered...

Laboratories". Bloomberg.com. Retrieved 2023-08-24. "Atrix Laboratories, Inc. (ATRX) Receives FDA Approval For Erythromycin/Benzoyl Peroxide", Biospace.com,...

Diagnosis of diffuse glioma, with astrocytomas mainly being diagnosed under IDH mutant and nuclear ATRX lost....

protein UBF, which binds to NOR DNA. In addition to UBF, NORs also bind to ATRX protein, treacle, sirtuin-7 and other proteins. UBF has been identified as...

HGNC:33499 Q8WXE1 1314 ATRN HGNC:885 O75882 1315 ATRNL1 HGNC:29063 Q5VV63 1316 ATRX HGNC:886 P46100 1317 ATXN1 HGNC:10548 P54253 1318 ATXN1L HGNC:33279 P0C7T5...

grade glioma, with a non-midline tumor location and with retained nuclear ATRX expression, immunohistochemical negativity for IDH1 R132H suffices for the...

proliferation and cell death); 3) mutations in the ATRX gene that encodes transcriptional regulator ATRX protein which contributes to regulating the expression...

VIPER-assessed activity of only four proteins (IRF3, ARL2BP, ZBTB17, and ATRX). The DarwinOncoMarker achieved a predictability measure (AUC = 0.862) in...

targets and aneuploidy links thymoma to myasthenia gravis. Sarcoma 206 TP53, ATRX, and RB1 among the few genes recurrently mutated across sarcoma types; copy...

play important roles in cancer, such as PIK3CA, IDH1, IDH2, ARID1A, ARID2, ATRX, DAXX, MLL2, MLL3, CIC, and RNF43. Vogelstein pioneered the idea that somatic...

Wickramasinghe J, Zheng H, Kossenkov AV, Lieberman PM (August 2022). "DAXX-ATRX regulation of p53 chromatin binding and DNA damage response". Nature Communications...

consists of three major protein domains: the Pro-Trp-Trp-Pro (PWWP) domain, the ATRX-DNMT3-DNMT3L (ADD) domain and the catalytic methyltransferase domain. The...

Xiao-Yang Liu; Noha Gerges; Andrey Korshunov; et al. (12 August 2012). "Frequent ATRX mutations and loss of expression in adult diffuse astrocytic tumors carrying...

X-linked mental retardation. The third gene located upstream of CXorf26 is ATRX, which encodes for an ATPase/helicase domain, and when mutated causes an...

founded to have a mutation of the gene in the ATRX on the X chromosome, also known as the Xq13 location. ATRX is a gene disease that is associated with other...

PML-NB disrupted cells were treated and Daxx relocalized with the PML-NB. ATRX, a centromeric heterochromatin component co-localizes with Daxx. This partnership...

has been used to detect germline mutations in human genes. For example, ATRX for X-linked mental retardation, and the HBB gene linked to β-thalassemia...

the regulation of the human alpha-globin gene cluster and the role of the ATRX protein in genetic disease" 2015 Irwin McLean "for his major contribution...

myelodysplasia syndrome, somatic; 300448; ATRX Alpha-thalassemia mental retardation syndrome; 301040; ATRX Alport syndrome; 301050; COL4A5 Alport syndrome...

associated with antiviral pathways such as PML, SP100, Daxx, and ATRX. In particular, Daxx and ATRX assemble viral DNA around histone 3, forming heterochromatin...

been shown to be cell cycle regulated via the chromatin-remodeling protein ATRX, with the highest expression of TERRA being present at the G1 phase following...