Amylin, or islet amyloid polypeptide (IAPP), is a 37-residue peptide hormone. It is co-secreted with insulin from the pancreatic β-cells in the ratio of...
33 KB (4,044 words) - 20:39, 24 August 2024
In molecular biology, the amylin protein family or calcitonin/CGRP/IAPP protein family is a family of proteins, which includes the precursors of calcitonin/calcitonin...
4 KB (379 words) - 05:03, 31 October 2023
Dual amylin and calcitonin receptor agonists (DACRAs) are a class of drugs that act as agonists at the amylin receptor and calcitonin receptor that are...
3 KB (351 words) - 20:55, 25 April 2024
Pramlintide (category Amylin receptor agonists)
(trade name Symlin) is an injectable amylin analogue drug for diabetes (both type 1 and 2), developed by Amylin Pharmaceuticals (now a wholly owned subsidiary...
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diabetes. CCL2 induces amylin expression through ERK1/ERK2/JNK-AP1 and NF-κB related signaling pathways independent of CCR2. Amylin upregulation by CCL2...
20 KB (2,419 words) - 10:18, 3 November 2024
gene-related peptide (CGRP) is a member of the calcitonin family of peptides consisting of calcitonin, amylin, adrenomedullin, adrenomedullin 2 (intermedin) and...
28 KB (3,124 words) - 07:02, 9 October 2024
tirzepatide, are also agonists of the GIP receptor, glucagon receptor, and/or amylin receptor. These additional targets are hoped to improve the amount of weight...
48 KB (5,003 words) - 18:46, 2 November 2024
evidence has been reached. This hormone stimulates growth hormone release. Amylin controls glucose homeostasis and gastric motility Glucose-dependent insulinotropic...
7 KB (349 words) - 14:57, 24 October 2023
Peptide (section Example families)
(POMC) peptides Enkephalin pentapeptides Prodynorphin peptides Calcitonin Amylin AGG01 Aromatic short peptides Biomimetic peptides Peptide amphiphiles Peptide...
22 KB (2,418 words) - 23:33, 30 July 2024
proposed debt swap. In April 2009, Icahn engaged in a proxy battle for Amylin. In September 2009, he offered to buy the shares of XO he did not already...
67 KB (5,592 words) - 22:23, 23 October 2024
Motilin (redirect from Motilin family)
Motilin is a 22-amino acid polypeptide hormone in the motilin family that, in humans, is encoded by the MLN gene. Motilin is secreted by endocrine Mo cells...
14 KB (1,604 words) - 05:45, 31 December 2023
amylin, a peptide hormone co-secreted with insulin from the pancreatic β cells. As plasma glucose levels recede, the subsequent reduction in amylin secretion...
26 KB (2,990 words) - 05:47, 27 October 2024
Relaxin family peptide hormones in humans are represented by seven members: three relaxin-like (RLN) and four insulin-like (INSL) peptides: RLN1, RLN2...
14 KB (1,400 words) - 17:08, 27 November 2023
hyperplasia indicates that use is contraindicated in people with a personal or family history of medullary thyroid carcinoma or with multiple endocrine neoplasia...
72 KB (6,068 words) - 15:16, 28 October 2024
The RFamide peptide family, or the RFamide-related peptides (RFRPs), are a family of neuropeptides. They are characterized by the possession of an Arg-Phe-NH2...
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date. Tirzepatide is contraindicated for use in people with a personal or family history of medullary thyroid cancer or for use in people with multiple endocrine...
44 KB (3,499 words) - 19:48, 29 October 2024
of these medications include the following: Pramlintide (Symlin): is an Amylin agonist. It acts centrally (via the brain) to reduce food intake and blood...
26 KB (2,906 words) - 20:42, 25 September 2024
Epidermal growth factor (redirect from EGF family)
EGF-family of proteins. Members of this protein family have highly similar structural and functional characteristics. Besides EGF itself other family members...
17 KB (1,708 words) - 22:30, 15 October 2024
(theophylline), diabetes drugs (acarbose, metformin, Alpha-glucosidase inhibitor, amylin analogs, GLP-1 receptor antagonists), antihypertensive medications (angiotensin...
32 KB (3,441 words) - 21:05, 3 November 2024
AstraZeneca (category Companies related to the Wallenberg family)
acquisition of the biotechnology company Amylin Pharmaceuticals. It was agreed that Bristol Myers Squibb would acquire Amylin for $5.3 billion in cash and the...
86 KB (7,963 words) - 18:33, 12 September 2024
endocrine pancreas and the gut. Amylin is another substance that can reduce body weight, and that may interact with IL-6. Amylin-induced IL-6 production in...
63 KB (7,473 words) - 05:58, 16 October 2024
when it agreed to buy Amylin Pharmaceuticals for around US$5.3 billion in cash and pay US$1.7 billion to Eli Lilly to cover Amylin's debt and its outstanding...
97 KB (7,693 words) - 20:50, 25 October 2024
cells in the anterior pituitary. The GHRHR is a member of the secretin family of G protein-coupled receptors, and is located on chromosome 7 in humans...
12 KB (1,281 words) - 15:01, 22 July 2024
action was linked to circulating blood fractions – now understood to be a family of androgenic hormones – in the early work on castration and testicular...
149 KB (15,703 words) - 16:01, 5 November 2024
Central Drugs Standard Control Organization, Dte.GHS, Ministry of Health and Family Welfare, Government of India. Archived from the original on 21 February...
151 KB (14,475 words) - 01:04, 25 October 2024
proteins that are made of acidic polypeptides and belongs to the TGF-B family. BMPs promote the regeneration of bone tissue and cartilage. BMP exhibits...
17 KB (2,024 words) - 16:54, 18 July 2024
who are pregnant is not recommended. Gliclazide is in the sulfonylurea family of medications. It works mostly by increasing the release of insulin. Gliclazide...
18 KB (1,514 words) - 15:51, 7 June 2024
2005. RAND Corporation: chairman of the board from 1981 to 1986; 1995–1996 Amylin Pharmaceuticals: director Secretary of Defense Donald Rumsfeld and Chairman...
180 KB (16,569 words) - 18:17, 1 November 2024
Administration for treating type 1 diabetes is the amylin analog pramlintide, which replaces the beta-cell hormone amylin. Addition of pramlintide to mealtime insulin...
108 KB (12,613 words) - 05:10, 3 November 2024
It is a releasing hormone that belongs to corticotropin-releasing factor family. In humans, it is encoded by the CRH gene. Its main function is the stimulation...
26 KB (2,916 words) - 17:06, 3 September 2024