• Thumbnail for Aspartate transaminase
    Aspartate transaminase (AST) or aspartate aminotransferase, also known as AspAT/ASAT/AAT or (serum) glutamic oxaloacetic transaminase (GOT, SGOT), is a...
    19 KB (2,115 words) - 13:27, 22 July 2023
  • Thumbnail for Alanine transaminase
    the appropriate terminology for AST and ALT are aspartate aminotransferase and alanine aminotransferase. The term transaminase is outdated and no longer...
    13 KB (1,370 words) - 19:23, 21 September 2024
  • Thumbnail for Malate–aspartate shuttle
    dehydrogenase in the mitochondrial matrix and intermembrane space. aspartate aminotransferase in the mitochondrial matrix and intermembrane space. malate-alpha-ketoglutarate...
    6 KB (801 words) - 19:00, 1 September 2024
  • In enzymology, an aspartate-prephenate aminotransferase (EC 2.6.1.78) is an enzyme that catalyzes the chemical reaction L-arogenate + oxaloacetate ⇌ {\displaystyle...
    2 KB (133 words) - 13:15, 26 August 2023
  • Thumbnail for Aspartic acid
    Aspartic acid (redirect from Aspartate)
    Aspartic acid (symbol Asp or D; the ionic form is known as aspartate), is an α-amino acid that is used in the biosynthesis of proteins. The L-isomer of...
    20 KB (1,867 words) - 15:34, 13 August 2024
  • Thumbnail for Transamination
    transamination reaction yielding aspartate. Glutamate + oxaloacetate ↔ α-ketoglutarate + aspartate Transamination catalyzed by aminotransferase occurs in two stages...
    5 KB (570 words) - 12:52, 22 July 2024
  • The biosynthesis of aspartate is a one step reaction that is catalyzed by a single enzyme. The enzyme aspartate aminotransferase catalyzes the transfer...
    61 KB (6,770 words) - 15:11, 20 August 2024
  • Thumbnail for GOT1
    Aspartate aminotransferase, cytoplasmic is an enzyme that in humans is encoded by the GOT1 gene. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent...
    7 KB (793 words) - 20:49, 13 October 2022
  • Thumbnail for Transaminase
    plays a key role in funneling nitrogen from amino acid metabolism to aspartate and glutamate for conversion to urea for excretion of nitrogen. In similar...
    8 KB (784 words) - 21:00, 13 April 2024
  • Thumbnail for Tovorafenib
    increased alanine aminotransferase, decreased albumin, decreased lymphocytes, decreased leukocytes, increased aspartate aminotransferase, decreased potassium...
    9 KB (513 words) - 05:52, 6 October 2024
  • Thumbnail for Imetelstat
    decreased neutrophils, increased aspartate aminotransferase, increased alkaline phosphatase, increased alanine aminotransferase, fatigue, prolonged partial...
    15 KB (714 words) - 05:23, 6 October 2024
  • ASM-135 ASAT, an air-launched anti-satellite multi-stage missile Aspartate aminotransferase, an enzyme in amino acid metabolism Association for Science in...
    295 bytes (68 words) - 18:35, 17 January 2024
  • Thumbnail for Purine nucleotide cycle
    ⇌ α-Ketoglutarate + Aspartate (catalyzed by aspartate aminotransferase) When skeletal muscle is at rest (ADP<ATP), the aspartate is no longer needed for...
    23 KB (2,658 words) - 11:45, 3 September 2024
  • tests for assessing liver damage include alanine aminotransferase (ALT), aspartate aminotransferase (AST), and alkaline phosphatase (ALP). Bilirubin may...
    24 KB (2,897 words) - 05:51, 21 July 2024
  • Thumbnail for Omaveloxolone
    include an increase in alanine transaminase and an increase of aspartate aminotransferase, which can be signs of liver damage, headache, nausea, abdominal...
    14 KB (1,011 words) - 07:36, 18 July 2024
  • Thumbnail for Theanine
    Actions on Hippocampal Neurons: Toward the Generation of Novel N-Methyl-d-aspartate Receptor Modulators Based on Its Backbone" (PDF). ACS Chemical Neuroscience...
    22 KB (2,092 words) - 17:25, 1 November 2024
  • Thumbnail for Mirvetuximab soravtansine
    were vision impairment, fatigue, increased aspartate aminotransferase, nausea, increased alanine aminotransferase, keratopathy, abdominal pain, decreased...
    12 KB (885 words) - 04:54, 21 September 2024
  • include increased levels of the liver enzymes alanine aminotransferase and aspartate aminotransferase (signs of possible liver problems), increased levels...
    17 KB (1,233 words) - 22:37, 20 September 2024
  • Thumbnail for Adagrasib
    increased aspartate aminotransferase, decreased sodium, decreased hemoglobin, increased creatinine, decreased albumin, increased alanine aminotransferase, increased...
    12 KB (751 words) - 20:10, 9 September 2024
  • Thumbnail for C4 carbon fixation
    sheath. Here, the OAA produced by PEPC is transaminated by aspartate aminotransferase to aspartate (ASP) which is the metabolite diffusing to the bundle sheath...
    38 KB (4,488 words) - 23:16, 8 May 2024
  • Thumbnail for Lurbinectedin
    decreased albumin, constipation, dyspnea, decreased sodium, increased aspartate aminotransferase, vomiting, cough, decreased magnesium and diarrhea. Lurbinectedin...
    20 KB (1,473 words) - 07:20, 19 September 2023
  • Thumbnail for GOT2
    Aspartate aminotransferase, mitochondrial is an enzyme that in humans is encoded by the GOT2 gene. Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent...
    13 KB (1,683 words) - 17:33, 17 July 2024
  • Thumbnail for Aminooxyacetic acid
    Aminooxyacetic acid inhibits aspartate aminotransferase, another PLP-dependent enzyme, which is an essential part of the malate-aspartate shuttle. The inhibition...
    12 KB (1,105 words) - 17:52, 17 May 2024
  • such as gamma glutamyl transferase (GGT), aspartate aminotransferase (AST), and alanine aminotransferase (ALT), carbohydrate-deficient transferrin can...
    4 KB (390 words) - 00:59, 5 August 2024
  • Thumbnail for Vorasidenib
    laboratory abnormalities include increased alanine aminotransferase, increased aspartate aminotransferase, GGT increased, and decreased neutrophils. Agios...
    15 KB (1,090 words) - 15:26, 1 November 2024
  • Thumbnail for Comprehensive metabolic panel
    protein (TP) Human serum albumin Bilirubin Alkaline phosphatase (ALP) Aspartate amino transferase (AST or SGOT) Alanine amino transferase (ALT or SGPT)...
    6 KB (500 words) - 01:14, 13 November 2023
  • transaminases, commonly the transaminases alanine transaminase (ALT) and aspartate transaminase (AST), may be an indicator of liver dysfunction. Other terms...
    11 KB (1,289 words) - 14:05, 25 June 2024
  • Thumbnail for Amino acid synthesis
    The oxaloacetate/aspartate family of amino acids is composed of lysine, asparagine, methionine, threonine, and isoleucine. Aspartate can be converted...
    31 KB (3,929 words) - 13:49, 28 June 2024
  • Thumbnail for Budd–Chiari syndrome
    may present with elevated liver enzymes; alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are often elevated in the acute phase and...
    22 KB (2,301 words) - 17:55, 30 September 2024
  • Thumbnail for Hypoalbuminemia
    protein, bilirubin, alkaline phosphatase, alanine aminotransferase (ALT), and aspartate aminotransferase (AST). This is commonly ordered when liver disease...
    23 KB (2,560 words) - 12:43, 28 August 2024