in humans is encoded by the BRDT gene. It is a member of the Bromodomain and Extra-terminal motif (BET) protein family. BRDT is similar to the RING3 protein...
5 KB (687 words) - 02:48, 19 December 2023
Bromodomain and Extra-Terminal motif (BET) proteins BRD2, BRD3, BRD4, and BRDT, and prevent protein-protein interaction between BET proteins and acetylated...
21 KB (2,514 words) - 21:48, 2 December 2023
67 sq mi) Population (31 December 2023) • Total 2,087,744 • Density 320/km2 (830/sq mi) GDP • Total €90.176 billion (2022) Website www.brdt.nrw.de...
5 KB (425 words) - 08:07, 20 August 2024
(bromodomain and extra terminal domain) family, which also includes BRD2, BRD3, and BRDT. BRD4, similar to other BET family members, contains two bromodomains that...
17 KB (2,120 words) - 14:32, 11 March 2024
proteins which include BRD2, BRD3, BRD4, and the testis-specific protein BRDT in mammals. BET inhibitors structurally similar to JQ1 are being tested in...
10 KB (892 words) - 06:20, 5 October 2024
HGNC:19874 Q9H0E9 1656 BRD9 HGNC:25818 Q9H8M2 1657 BRD10 HGNC:23378 Q5HYC2 1658 BRDT HGNC:1105 Q58F21 1659 BRF1 HGNC:11551 Q92994 1660 BRF2 HGNC:17298 Q9HAW0...
277 KB (17 words) - 18:34, 6 October 2024
and monkeys, though the mechanism of action requires more clarification. BRDT inhibitors such as JQ1 have been shown to produce reversible sterility in...
145 KB (15,377 words) - 20:44, 30 September 2024
reagent dispenser, a piece of laboratory equipment BRD2, BRD3, BRD4 and BRDT, bromodomain families Business requirements document Bycatch reduction device...
1 KB (177 words) - 04:40, 10 October 2024
extraterminal domain) family. Members of this family include BRD2, BRD3, BRD4 and BRDT. However proteins such as ASH1L also contain a bromodomain. Dysfunction of...
12 KB (1,243 words) - 11:42, 3 December 2023
mice – injection of a solution of the JQ1 molecule to bind to a pocket of BRDT necessary for chromatin remodeling, which gives the proteins that regulate...
59 KB (6,864 words) - 11:57, 2 November 2024
Germany and media sometimes used the abbreviations BR Deutschland, BR-Dt., BRDt., BR Dtld. or simply Dtld. After the newly established states of the German...
27 KB (2,892 words) - 16:47, 23 October 2024
Zdrojewicz, Zygmunt; Konieczny, Radosław; Papier, Paulina; Szten, Filip (2015). "Brdt Bromodomains Inhibitors and Other Modern Means of Male Contraception". Advances...
12 KB (1,413 words) - 21:54, 12 August 2024
Extra-Terminal motif (BET) protein family that also contains BRD3, BRD4, and BRDT in mammals Early descriptions demonstrated that BRD2 gene product is a mitogen-activated...
10 KB (1,177 words) - 14:20, 18 July 2024
nucleosomal histones. Recently, four members of the BET family, BRD2, 3, 4, and BRDT, each containing two bromodomains, were identified as important regulators...
21 KB (2,510 words) - 19:34, 18 March 2024
Govin J, et al. (2003). "Acetylation-dependent chromatin reorganization by BRDT, a testis-specific bromodomain-containing protein". Mol. Cell. Biol. 23 (15):...
8 KB (1,010 words) - 23:13, 31 March 2024
does not have a long C-terminal domain as BET family proteins BRD4 and BRDT do. Like other BET protein family members, BRD3 associates with acetylated...
10 KB (1,230 words) - 01:24, 28 March 2022
Tetrahedron 2018, 74, 2769–2774. Miao, Z.; Guan, X.; Jiang, J.; Georg, G. I. BRDT Inhibitors for Male Contraceptive Drug Discovery: Current Status. In Targeting...
8 KB (832 words) - 12:59, 13 August 2024
2022-05-26. Matzuk, Martin M.; et al. (2012). "Small-Molecule Inhibition of BRDT for Male Contraception". Cell. 150 (4). Elsevier BV: 673–684. doi:10.1016/j...
397 KB (38,864 words) - 17:28, 12 September 2024