• Thumbnail for Bortezomib
    Bortezomib, sold under the brand name Velcade among others, is an anti-cancer medication used to treat multiple myeloma and mantle cell lymphoma. This...
    24 KB (2,260 words) - 18:03, 5 October 2024
  • Thumbnail for Multiple myeloma
    improved outcomes with new chemotherapy regimens, e.g., with bortezomib. Treatment with bortezomib, melphalan, and prednisone had an estimated overall survival...
    131 KB (13,506 words) - 14:34, 29 September 2024
  • Bortezomib/dexamethasone is a combination drug against multiple myeloma. When bortezomib is used by the trade name Velcade, the combination is called Vel/Dex...
    2 KB (94 words) - 10:49, 13 September 2024
  • Thumbnail for Proteasome
    been exploited in several recently developed chemotherapy agents such as bortezomib and salinosporamide A. In response to cellular stresses – such as infection...
    105 KB (12,670 words) - 08:02, 23 August 2024
  • Thumbnail for Daratumumab
    Administration (FDA) approved daratumumab for use in combination with bortezomib, melphalan and prednisone to include the treatment of people with newly...
    22 KB (1,836 words) - 05:53, 21 September 2024
  • Exatecan Gimatecan Irinotecan Topotecan Etoposide Teniposide Tafluposide Bortezomib Erlotinib Gefitinib Imatinib Vemurafenib Vismodegib Azacitidine Azathioprine...
    5 KB (324 words) - 12:07, 20 July 2024
  • Thumbnail for Carfilzomib
    have received at least two prior therapies, including treatment with bortezomib and an immunomodulatory therapy (such as lenalidomide) and have demonstrated...
    19 KB (1,730 words) - 05:43, 7 April 2024
  • Thumbnail for Lenalidomide
    the drug combinations of lenalidomide plus dexamethasone and continuous bortezomib plus lenalidomide plus dexamethasone probably result in an increase of...
    29 KB (2,483 words) - 05:43, 9 August 2024
  • Thumbnail for Dexamethasone
    (Thal-dex), lenalidomide, bortezomib (Velcade, Vel-dex), or a combination of doxorubicin (Adriamycin) and vincristine or bortezomib/lenalidomide/dexamethasone...
    68 KB (5,999 words) - 20:41, 31 August 2024
  • amyloidosis who received daratumumab/hyaluronidase in combination with bortezomib, cyclophosphamide, and dexamethasone are upper respiratory tract infection...
    11 KB (954 words) - 06:56, 8 August 2024
  • Thumbnail for Selinexor
    December 2020, selinexor was approved by the FDA in combination with bortezomib and dexamethasone for the treatment of adults with multiple myeloma who...
    30 KB (2,715 words) - 06:09, 16 July 2024
  • been the results of that research. It is particularly known for bringing bortezomib (marketed as Velcade) through clinical trials to approval for treatment...
    13 KB (1,244 words) - 02:54, 21 May 2024
  • for those ineligible for a stem cell transplant is cyclophosphamide, bortezomib and dexamethasone (CyBorD) with daratumumab added. Daratumumab, a monoclonal...
    16 KB (1,638 words) - 20:43, 24 September 2024
  • Thumbnail for Proteasome inhibitor
    cells dependent upon suppression of pro-apoptotic pathways. For example, bortezomib causes a rapid and dramatic change in the levels of intracellular peptides...
    9 KB (1,094 words) - 16:23, 3 December 2023
  • Thumbnail for Ixazomib
    include diarrhea, constipation and low platelet count. Like the older bortezomib (which can only be given by injection), it acts as a proteasome inhibitor...
    17 KB (1,693 words) - 06:49, 1 July 2024
  • Thumbnail for Amino acid
    drugs, such as Bortezomib and MG132, are artificially synthesized and retain their protecting groups, which have specific codes. Bortezomib is Pyz–Phe–boroLeu...
    98 KB (10,141 words) - 19:21, 21 September 2024
  • include bortezomib-based treatment, an autologous stem cell transplant, and if the patient is considered eligible, an organ transplant. Bortezomib is frequently...
    16 KB (1,734 words) - 20:00, 20 December 2023
  • Thumbnail for Plasma cell leukemia
    particularly bortezomib, and/or autologous stem-cell transplantation have improved pPCL survival. For example, 28 patients treated with a bortezomib-based induction...
    18 KB (2,169 words) - 04:28, 24 June 2024
  • (February 2009). "Complete remission of primary plasma cell leukemia with bortezomib, doxorubicin, and dexamethasone: a case report". Cases J. 2 (1): 121....
    70 KB (2,582 words) - 03:15, 16 December 2023
  • Thumbnail for Pomalidomide
    medication. In the European Union, pomalidomide, in combination with bortezomib and dexamethasone, is indicated in the treatment of adults with multiple...
    18 KB (1,273 words) - 10:05, 17 June 2024
  • function.[better source needed] In 2012, 20 patients with thalidomide and bortezomib induced neuropathy were reported to have improved nerve functions and...
    47 KB (5,039 words) - 04:14, 20 September 2024
  • Thumbnail for Cell death
    caused by some cytostatic agents such as anthracyclines, oxaliplatin and bortezomib, or radiotherapy and photodynamic therapy (PDT). Pyroptosis is a highly...
    16 KB (1,909 words) - 19:13, 26 September 2024
  • disappearance of the symptoms of the TEMPI syndrome was reported with the drugs bortezomib, daratumumab and autologous stem cell transplantation. In 2010, the case...
    5 KB (363 words) - 15:45, 21 September 2024
  • Thumbnail for Tretinoin
    inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib Carfilzomib Oprozomib Ixazomib PhI (Anagrelide) IMPDI (Tiazofurin§) LI...
    31 KB (2,908 words) - 06:38, 22 September 2024
  • Thumbnail for Boron
    antiseptics. Bortezomib (marketed as Velcade and Cytomib). Boron appears as an active element in the organic pharmaceutical bortezomib, a new class of...
    127 KB (13,477 words) - 16:02, 23 September 2024
  • Thumbnail for Boronic acid
    transmetallation of its organic residue to a transition metal. The compound bortezomib with a boronic acid group is a drug used in chemotherapy. The boron atom...
    27 KB (2,662 words) - 03:08, 9 November 2023
  • Thumbnail for Iberdomide
    CC-220) in Combination with Dexamethasone (DEX) and Daratumumab (DARA) or Bortezomib (BORT) in Patients with Relapsed/Refractory Multiple Myeloma (RRMM)"....
    11 KB (746 words) - 15:52, 3 June 2024
  • Thumbnail for Green tea
    inconclusive at present". Green tea interferes with the chemotherapy drug bortezomib (Velcade) and other boronic acid-based proteasome inhibitors, and should...
    62 KB (7,065 words) - 22:48, 9 September 2024
  • Thumbnail for Methotrexate
    inhibitors (Abemaciclib Alvocidib† Palbociclib Ribociclib Seliciclib†) PrI Bortezomib Carfilzomib Oprozomib Ixazomib PhI (Anagrelide) IMPDI (Tiazofurin§) LI...
    36 KB (3,278 words) - 07:36, 30 September 2024
  • Thumbnail for Chemotherapy
    symptom of systemic lupus erythematosus. Dexamethasone along with either bortezomib or melphalan is commonly used as a treatment for AL amyloidosis. Recently...
    155 KB (17,546 words) - 16:49, 16 August 2024