• Thumbnail for CCR4
    chemokine receptor type 4 is a protein that in humans is encoded by the CCR4 gene. CCR4 has also recently been designated CD194 (cluster of differentiation...
    4 KB (520 words) - 09:06, 4 November 2023
  • Thumbnail for CCR4-Not
    Carbon Catabolite Repression—Negative On TATA-less, or CCR4-Not, is a multiprotein complex that functions in gene expression. The complex has multiple...
    10 KB (915 words) - 00:46, 14 June 2024
  • afucosylated monoclonal antibody targeting CC chemokine receptor type 4 (CCR4). It is given by injection into a vein. The most common side effects include...
    14 KB (957 words) - 14:32, 14 June 2024
  • Thumbnail for Exonuclease
    degradation. CCR4 has been found to contain RNA and single-stranded DNA 3' to 5' exonuclease activities. Another component associated with the CCR4-Not is CAF1...
    11 KB (1,424 words) - 20:56, 21 June 2024
  • Thus CCR3 plays a role in allergic reactions. CCR3 is also known as CD193. CCR4 is expressed on Th2 T lymphocytes and is up-regulated by T cell receptor...
    19 KB (1,726 words) - 12:13, 3 December 2023
  • Thumbnail for CNOT11
    CCR4-NOT transcription complex subunit 11 is a protein that in humans is encoded by the CNOT11 gene. It is a subunit of the CCR4-Not deadenylase complex...
    830 bytes (123 words) - 21:00, 3 March 2023
  • Thumbnail for Phospholipid
    are required for directional migration of T lymphocytes in response to the CCR4 ligands CCL17 and CCL22". Journal of Leukocyte Biology. 79 (6): 1369–1380...
    23 KB (1,723 words) - 18:17, 15 July 2024
  • Thumbnail for CNOT2
    CCR4-NOT transcription complex subunit 2 is a protein that in humans is encoded by the CNOT2 gene. It is a subunit of the CCR4-Not deadenylase complex...
    4 KB (501 words) - 12:05, 1 August 2023
  • Thumbnail for CNOT3
    CCR4-NOT transcription complex subunit 3 is a protein that in humans is encoded by the CNOT3 gene. It is a subunit of the CCR4-Not deadenylase complex...
    3 KB (394 words) - 02:50, 17 April 2022
  • Thumbnail for CNOT6L
    CCR4-NOT transcription complex subunit 6 like is a protein that in humans is encoded by the CNOT6L gene. It is a paralog of CNOT6 and therefore a potential...
    4 KB (527 words) - 06:10, 13 October 2022
  • skin but CCR5 is higher in lesional skin. CCR4 is receptor typically expressed in lesional skin only. CCR4 is a receptor for TARC. These differences in...
    4 KB (500 words) - 12:19, 16 January 2024
  • Thumbnail for CNOT9
    CCR4-NOT transcription complex subunit 9 is a protein that in humans is encoded by the CNOT9 gene. This gene encodes a member of the highly conserved RCD1...
    4 KB (620 words) - 21:00, 3 March 2023
  • Thumbnail for CNOT1
    CCR4-NOT transcription complex subunit 1 is a protein that in humans is encoded by the CNOT1 gene. It is a part of the CCR4-Not complex, which deadenylates...
    7 KB (730 words) - 13:52, 28 October 2022
  • Thumbnail for CNOT8
    CCR4-NOT transcription complex subunit 8 is a protein that in humans is encoded by the CNOT8 gene. It is a subunit of the CCR4-Not deadenylase complex...
    7 KB (930 words) - 09:40, 17 October 2022
  • Thumbnail for CNOT4
    CCR4-NOT transcription complex, subunit 4 is a protein that in humans is encoded by the CNOT4 gene. The protein encoded by this gene is a subunit of the...
    5 KB (572 words) - 20:45, 22 January 2024
  • Thumbnail for Ubiquitin
    CCL15 CCL18 CCL24 CCL26 CCL28 CCR4 Agonists: CCL3 (MIP-1α) CCL5 (RANTES) CCL17 CCL22 Antibodies: Mogamulizumab (against CCR4) CCR5 Agonists: CCL3 (MIP-1α)...
    98 KB (11,068 words) - 18:53, 17 August 2024
  • and HLA-DR15 (mean age of two groups: 34 and 21 years), FOXP3, CD95, and CCR4; lower expression of CD45RA (mean age: 45 years); and expression of the IL-2/STAT5...
    40 KB (4,353 words) - 06:51, 24 August 2024
  • CCR4: Dave Halley scored his 1st four-try haul and 1st hat-trick for the Bulls. CCR4: Glenn Morrison scored his 1st hat-trick for the Bulls. CCR4: Semi...
    21 KB (304 words) - 21:00, 14 April 2024
  • Thumbnail for List of therapeutic monoclonal antibodies
    EGFR extracellular domain III cancer Mogamulizumab Poteligeo mab humanized CCR4 Y adult T-cell leukemia/lymphoma Monalizumab mab humanized NKG2A rheumatoid...
    136 KB (4,020 words) - 07:14, 15 August 2024
  • Thumbnail for Post-transcriptional modification
    protects the 3'end from ribonuclease digestion by enzymes including the CCR4-Not complex. RNA splicing is the process by which introns, regions of RNA...
    11 KB (1,432 words) - 23:35, 24 July 2024
  • Thumbnail for CNOT7
    CCR4-NOT transcription complex subunit 7 is a protein that in humans is encoded by the CNOT7 gene. It is a subunit of the CCR4-Not deadenylase complex...
    10 KB (1,308 words) - 08:33, 10 February 2024
  • infiltration into the TMEis facilitated by the binding of the chemokine receptor CCR4, which is expressed on Treg cells, to its ligand CCL22, which is secreted...
    79 KB (9,493 words) - 15:51, 21 June 2024
  • Thumbnail for CNOT10
    CCR4-NOT transcription complex subunit 10 is a protein that in humans is encoded by the CNOT10 gene. It is a subunit of the CCR4-Not deadenylase complex...
    834 bytes (123 words) - 22:06, 3 March 2023
  • Thumbnail for CCL17
    binding to CCR4, a chemokine receptor expressed on type 2 helper T cells, cutaneous lymphocyte skin-localizing T cells, and regulatory T cells. CCR4 is also...
    33 KB (3,907 words) - 11:29, 29 July 2024
  • Thumbnail for Adult T-cell leukemia/lymphoma
    and cytotoxic markers. Additionally, there is partial positivity for CD30, CCR4, and FOXP3. Treatment options that have been tried include zidovudine and...
    17 KB (1,966 words) - 20:15, 28 August 2024
  • Thumbnail for CNOT6
    CCR4-NOT transcription complex subunit 6 is a protein that in humans is encoded by the CNOT6 gene. The protein encoded by this gene is a subunit of the...
    4 KB (522 words) - 07:54, 3 December 2023
  • Thumbnail for Smaug (protein)
    binding of eIF4G to eIF4E). There after it recruits deadenylation complex CCR4-Not on to the nanos mRNA which leads to deadenylation and subsequent decay...
    10 KB (1,076 words) - 10:16, 6 March 2024
  • Thumbnail for Conolidine
    CCL15 CCL18 CCL24 CCL26 CCL28 CCR4 Agonists: CCL3 (MIP-1α) CCL5 (RANTES) CCL17 CCL22 Antibodies: Mogamulizumab (against CCR4) CCR5 Agonists: CCL3 (MIP-1α)...
    10 KB (962 words) - 22:42, 28 August 2024
  • Thumbnail for Chemokine
    their surface express several receptors for chemokines: CCR1, CCR2, CCR3, CCR4, CCR5, CXCR2, and CXCR4. Ligands of these receptors CCL2 and CCL5 play an...
    30 KB (2,931 words) - 10:43, 29 July 2024
  • Thumbnail for CCR5
    CC CCR1 / CCRL1 CCR2 CCRL2 CCR3 CCR4 CCR5 CCR6 CCR7 CCR8 CCR9 CCR10 CXC IL-8 CXCR1 CXCR2 CXCR3 CXCR4 CXCR5 CXCR6 CXCR7 Other CX3C CX3CR1 XC XCR1 CCBP2...
    67 KB (7,845 words) - 11:20, 5 August 2024