A calpain (/ˈkælpeɪn/; EC 3.4.22.52, EC 3.4.22.53) is a protein belonging to the family of calcium-dependent, non-lysosomal cysteine proteases (proteolytic...
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Calpain-2 (EC 3.4.22.53, calcium-activated neutral protease II, m-calpain, milli-calpain) is an intracellular heterodimeric calcium-activated cysteine...
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Calpain-3 is a protein that in humans is encoded by the CAPN3 gene. Calpain, a heterodimer consisting of a large and a small subunit, is a major intracellular...
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Calpain-9 is a protein that in humans is encoded by the CAPN9 gene. Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases...
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Calpain-6 (also known as calpamodulin) is a protein in humans that is encoded by the CAPN6 gene. Calpains are a ubiquitous, well-conserved family of calcium-dependent...
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Calpain-1 (EC 3.4.22.52, mu-calpain, calcium-activated neutral protease I) is an enzyme. This enzyme catalyses the following chemical reaction Broad endopeptidase...
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Calpain-1 catalytic subunit (CANP 1) is a protein that in humans is encoded by the CAPN1 gene. The calpains, calcium-activated neutral proteases, are...
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Calpain-8 is a protein in humans that is encoded by the CAPN8 gene. GRCh38: Ensembl release 89: ENSG00000203697 – Ensembl, May 2017 GRCm38: Ensembl release...
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Calpain-2 catalytic subunit is a protein that in humans is encoded by the CAPN2 gene. The calpains, calcium-activated neutral proteases, are nonlysosomal...
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cell is calpain, a Ca2+-dependent non-lysosomal protease. About 15 minutes to half an hour after the onset of injury, a process called calpain-mediated...
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Calpain small subunit 1 (CSS1) is a protein that in humans is encoded by the CAPNS1 gene. Calpains are a ubiquitous, well-conserved family of calcium-dependent...
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CAPN10 (redirect from Calpain-10)
Calpain-10 is a protein that in humans is encoded by the CAPN10 gene. Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases...
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dysregulation plays a role. Calpain 3 is unique from other calpain proteases in that it is relatively specific to muscle. Calpain 3 is both a protease and...
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reactions. The enzymes involved are proteinases (cathepsins – B, D, H & L, and calpains) and exopeptidases (peptidase and aminopeptidase). These enzymes cause...
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including: Z line region: telethonin and alpha-actinin I band region: calpain-3 and obscurin M line region: myosin-binding protein C, calmodulin 1, CAPN3...
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is that the calcium-dependent protease calpain is involved: it has been shown that the inhibition of calpain leads to the inhibition of focal adhesion-ECM...
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the United States, in descending order, are those due to mutation of 1) calpain, 2) dysferlin, 3) collagen VI, 4) sarcoglycans, 5) anoctamin 5, and 6)...
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peptide for protein degradation. This may be mediated via the proteasome or calpain. Rogers S, Wells R, Rechsteiner M (1986). "Amino acid sequences common...
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Chishti A, Bi X, Baudry M (November 2013). "Distinct roles for μ-calpain and m-calpain in synaptic NMDAR-mediated neuroprotection and extrasynaptic NMDAR-mediated...
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abnormalities: Bernard–Soulier syndrome, velocardiofacial syndrome Caused by calpain defect: Montreal platelet syndrome Caused by alpha granules defect: gray...
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an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains...
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activity, which also can cause apoptosis via a calcium binding protease calpain. The intrinsic pathway is also known as the mitochondrial pathway. Mitochondria...
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eventually disintegrate. The disintegration is dependent on ubiquitin and calpain proteases (caused by the influx of calcium ion), suggesting that axonal...
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H. A. (2008). Effect of two dietary concentrate levels on tenderness, calpain, and calpastatin activities, and cacass merit in Waguli and Brahman steers...
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is a protease inhibitor that also acts as an inhibitor of calpain Melanostatin (prolyl-leucyl-glycinamide) is a peptide hormone produced...
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enzymes, including phospholipases, endonucleases, and proteases such as calpain. These enzymes go on to damage cell structures such as components of the...
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Ashraf MZ (February 2014). "Altered expression of platelet proteins and calpain activity mediate hypoxia-induced prothrombotic phenotype". Blood. 123 (8):...
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axonal injury, spectrin is irreversibly cleaved by the proteolytic enzyme calpain, destroying the cytoskeleton. Spectrin cleavage causes the membrane to...
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(Carica papaya), bromelain (Ananas comosus), cathepsin K (liverwort) and calpain (Homo sapiens) CD C11, C13, C14, C25, C50, C80, C84 Caspase 1 (Rattus norvegicus)...
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