• Thumbnail for Cathepsin G
    Cathepsin G is a protein that in humans is encoded by the CTSG gene. It is one of the three serine proteases of the chymotrypsin family that are stored...
    24 KB (2,860 words) - 07:04, 3 January 2024
  • Thumbnail for Cathepsin
    protease) Cathepsin F (cysteine proteinase) Cathepsin G (serine protease) Cathepsin H (cysteine protease) Cathepsin K (cysteine protease) Cathepsin L1 (cysteine...
    20 KB (2,371 words) - 22:28, 25 April 2024
  • Thumbnail for Cathepsin B
    Cathepsin B belongs to a family of lysosomal cysteine proteases known as the cysteine cathepsins and plays an important role in intracellular proteolysis...
    12 KB (1,346 words) - 00:48, 3 December 2023
  • Thumbnail for Neutrophil elastase
    to other cytotoxic immune serine proteases, such as the granzymes and cathepsin G. It is more distantly related to the digestive CELA1. The neutrophil...
    9 KB (1,111 words) - 20:35, 7 May 2024
  • Thumbnail for Cathepsin D
    Cathepsin D is a protein that in humans is encoded by the CTSD gene. This gene encodes a lysosomal aspartyl protease composed of a protein dimer of disulfide-linked...
    22 KB (2,616 words) - 02:37, 10 March 2024
  • Thumbnail for Cathepsin C
    Cathepsin C (CTSC) also known as dipeptidyl peptidase I (DPP-I) is a lysosomal exo-cysteine protease belonging to the peptidase C1 protein family, a subgroup...
    15 KB (1,845 words) - 10:11, 3 December 2023
  • Thumbnail for Neutrophil extracellular traps
    NETs contain proteins from azurophilic granules (neutrophil elastase, cathepsin G and myeloperoxidase), specific granules (lactoferrin), tertiary granules...
    26 KB (3,020 words) - 15:40, 20 February 2024
  • serine proteases, bactericidal permeability-increasing protein, lysozyme, cathepsin G, proteinase 3, and proteoglycans.[citation needed] Azurophil granules...
    3 KB (216 words) - 19:28, 5 December 2023
  • Thumbnail for Protease
    immune system. Other proteases are present in leukocytes (elastase, cathepsin G) and play several different roles in metabolic control. Some snake venoms...
    26 KB (2,799 words) - 15:02, 30 June 2024
  • Thumbnail for Cathepsin S
    Cathepsin S is a protein that in humans is encoded by the CTSS gene. Transcript variants utilizing alternative polyadenylation signals exist for this...
    17 KB (2,262 words) - 22:29, 25 April 2024
  • Thumbnail for Anti-neutrophil cytoplasmic antibody
    MPO. p-ANCA without nuclear extension occurs with antibodies to BPI, cathepsin G, elastase, lactoferrin and lysozyme. GS-ANA are antibodies directed to...
    20 KB (2,245 words) - 16:12, 21 June 2024
  • Thumbnail for P-ANCA
    result in a p-ANCA pattern. These include lactoferrin, elastase, and cathepsin G.[citation needed] When the condition is a vasculitis, the target is usually...
    4 KB (445 words) - 21:42, 28 February 2024
  • Thumbnail for Serpin
    2 is a novel serpin that inhibits the chymotrypsin-like proteinases cathepsin G and mast cell chymase". The Journal of Biological Chemistry. 272 (3):...
    136 KB (14,251 words) - 15:12, 4 May 2024
  • Thumbnail for Interleukin-1 family
    IL-33109-270, which are processed from a precursor by serine proteases cathepsin G and elastase, are even more potent activators of inflammatory responses...
    49 KB (6,005 words) - 16:30, 10 June 2024
  • Thumbnail for Cathepsin K
    Cathepsin K, abbreviated CTSK, is an enzyme that in humans is encoded by the CTSK gene. The protein encoded by this gene is a cysteine cathepsin, a lysosomal...
    15 KB (1,710 words) - 16:04, 7 November 2023
  • proteases expressed by innate immune cells, such as neutrophil elastase and cathepsin G. Granzyme B activates apoptosis by activating caspases (especially caspase-3)...
    14 KB (1,786 words) - 13:08, 2 June 2024
  • Thumbnail for Granulocyte
    parasites (e.g., enteric nematodes) because their granules contain a unique, toxic basic protein and cationic protein (e.g., cathepsin); receptors that...
    22 KB (2,352 words) - 06:41, 29 April 2024
  • Thumbnail for Neutrophil
    neutrophils minimizes propagation of those pathogens that parasitize phagocytes (e.g. Leishmania) because the more time such parasites spend outside a host cell...
    52 KB (5,608 words) - 04:26, 29 June 2024
  • metalloproteases, cathepsin G, plasmin, urokinase plasminogen activator (uPA, or urokinase), and in the GPI anchor (phospholipase C and D, cathepsin G, plasmin)...
    13 KB (1,767 words) - 18:16, 12 March 2024
  • Thumbnail for Sodium aurothiomalate
    the following enzymes: Acid phosphatase Beta-glucuronidase Elastase Cathepsin G Thrombin Microsomal prostaglandin E synthase-1 Reports of favorable use...
    8 KB (701 words) - 02:17, 28 March 2024
  • to infiltrate organs such as the lung. [citation needed] Mediation by cathepsin G has been suggested. The treatment of RAS usually involves administering...
    3 KB (357 words) - 22:57, 4 February 2024
  • Thumbnail for Cathepsin L2
    Cathepsin L2 (EC 3.4.22.43, also known as cathepsin V or cathepsin U) is a protein encoded in humans by the CTSV gene. The protein is a human cysteine...
    8 KB (1,017 words) - 22:41, 2 April 2024
  • Thumbnail for Osteoclast
    Several other cathepsins are expressed in osteoclasts including cathepsins B, C, D, E, G, and L. The function of these cysteine and aspartic proteases is...
    26 KB (2,925 words) - 20:28, 17 May 2024
  • Thumbnail for Cathepsin E
    non-pepsin proteinase, cathepsin D-like acid proteinase, cathepsin E-like acid proteinase, cathepsin D-type proteinase) is an enzyme. Cathepsin E is a protease...
    18 KB (2,278 words) - 03:10, 24 December 2023
  • Thumbnail for Cathepsin Z
    cathepsin B, cathepsin C, cathepsin F, cathepsin H, cathepsin K, cathepsin L, cathepsin L2 or V, cathepsin O, cathepsin S, cathepsin Z, and cathepsin...
    15 KB (1,787 words) - 22:29, 25 April 2024
  • Thumbnail for Cathepsin L1
    Cathepsin L1 is a protein that in humans is encoded by the CTSL1 gene. The protein is a cysteine cathepsin, a lysosomal cysteine protease that plays a...
    14 KB (1,708 words) - 00:31, 22 June 2024
  • Thumbnail for Cathepsin F
    Cathepsin F is a protein that in humans is encoded by the CTSF gene. Cysteine cathepsins are a family of cysteine proteases that represent a major component...
    8 KB (990 words) - 17:07, 29 May 2024
  • Thumbnail for LEKTI
    inhibits the exogenous serine proteases trypsin, plasmin, subtilisin A, cathepsin G and human neutrophil elastase. LEKTI may play a role in skin and hair...
    10 KB (1,230 words) - 16:10, 5 March 2024
  • Thumbnail for Alpha 1-antichymotrypsin
    1-antichymotrypsin inhibits the activity of certain enzymes called proteases, such as cathepsin G that is found in neutrophils, and chymases found in mast cells, by cleaving...
    4 KB (475 words) - 00:49, 14 October 2022
  • Thumbnail for Cathepsin H
    kidney cathepsin H". Biol Chem Hoppe-Seyler. 369 (6): 469–75. doi:10.1515/bchm3.1988.369.1.469. PMID 2849458. "Entrez Gene: CTSH cathepsin H". Sawicki G, Warwas...
    8 KB (938 words) - 01:57, 4 March 2023