• Thumbnail for Kinetochore
    A kinetochore (/kɪˈnɛtəkɔːr/, /-ˈniːtəkɔːr/) is a disc-shaped protein structure associated with duplicated chromatids in eukaryotic cells where the spindle...
    65 KB (7,839 words) - 18:06, 1 July 2024
  • Thumbnail for Spindle apparatus
    Depolymerization of microtubules generates tension at kinetochores; bipolar attachment of sister kinetochores to microtubules emanating from opposite cell poles...
    28 KB (3,300 words) - 12:32, 30 September 2024
  • Spindle and kinetochore-associated protein 2 is a protein that in humans is encoded by the SKA2 gene found in chromosome 17. SKA2 is a part of a spindle...
    12 KB (1,492 words) - 06:13, 17 September 2021
  • Thumbnail for Spindle checkpoint
    the kinetochores of the chromosomes, as well as the alignment of the chromosomes in the middle of the cell. Each chromatid has its own kinetochore, and...
    73 KB (9,145 words) - 07:11, 31 August 2024
  • Thumbnail for Centromere
    the centromere via the kinetochore. The physical role of the centromere is to act as the site of assembly of the kinetochores – a highly complex multiprotein...
    40 KB (4,197 words) - 01:49, 16 October 2024
  • homolog, kinetochore complex component pseudogene is a mouse pseudogene with symbol 2700099C18Rik. "Entrez Gene: NDC80 homolog, kinetochore complex component...
    547 bytes (37 words) - 13:41, 24 July 2024
  • Thumbnail for Metaphase
    centrosomes on opposite poles of the cell have completed attachment to kinetochores on condensed chromosomes. The centromeres of the chromosomes convene...
    6 KB (555 words) - 17:31, 16 September 2024
  • Thumbnail for Prometaphase
    composed of two types, kinetochore microtubules and non-kinetochore microtubules. Kinetochore microtubules begin searching for kinetochores to attach to. A number...
    4 KB (337 words) - 15:31, 7 March 2024
  • Thumbnail for Mitosis
    envelope. In late prometaphase, kinetochore microtubules begin to search for and attach to chromosomal kinetochores. A kinetochore is a proteinaceous microtubule-binding...
    71 KB (7,317 words) - 12:42, 26 August 2024
  • Thumbnail for Aster (cell biology)
    the kinetochore microtubules extending from each centrosome connect to the centromeres of the chromosomes. Next, during anaphase, the kinetochore microtubules...
    5 KB (631 words) - 13:52, 4 October 2024
  • Thumbnail for Anaphase
    involved in creating the forces necessary to separate the chromatids: kinetochore microtubules, interpolar microtubules, and astral microtubules. The centromeres...
    6 KB (719 words) - 02:00, 2 May 2024
  • Thumbnail for Microtubule
    attach to the kinetochores can aid in chromosome congregation through lateral interaction with the kinetochores. K fibers/Kinetochore microtubules are...
    64 KB (7,838 words) - 19:01, 10 September 2024
  • emanating from different microtubule organizing centres (MTOCs) attach to kinetochores of sister chromatids. This results in the sister chromatids moving to...
    4 KB (482 words) - 06:01, 15 November 2023
  • Thumbnail for Meiosis
    chromosome kinetochores form end-on attachments to microtubules. Homologous pairs move together along the metaphase plate: As kinetochore microtubules...
    64 KB (7,478 words) - 23:27, 22 August 2024
  • Thumbnail for NDC80
    Kinetochore protein NDC80 homolog is a protein that in humans is encoded by the NDC80 gene. Ndc80 is one of the proteins of outer kinetochore. It forms...
    10 KB (1,178 words) - 15:32, 6 April 2024
  • Thumbnail for DNA replication factor CDT1
    negative regulation of protein localization to kinetochore positive regulation of protein localization to kinetochore positive regulation of DNA-dependent DNA...
    12 KB (1,439 words) - 01:55, 12 October 2024
  • Holocentric chromosomes are chromosomes that possess multiple kinetochores along their length rather than the single centromere typical of other chromosomes...
    43 KB (4,763 words) - 10:49, 21 July 2024
  • Thumbnail for Chromatid
    material during the prophase I of meiosis (See Homologous chromosome pair). Kinetochore Look up chromatid in Wiktionary, the free dictionary. "What is a Chromatid...
    4 KB (326 words) - 00:14, 27 June 2024
  • the Shugoshin protein in eukaryotes. It has a role in attaching to the kinetochores, structures on the chromatids where microtubules attach. Shugoshin has...
    5 KB (552 words) - 21:30, 21 February 2024
  • Thumbnail for CENPA
    is a histone H3 variant which is the critical factor determining the kinetochore position(s) on each chromosome in most eukaryotes including humans. CENPA...
    17 KB (1,927 words) - 22:46, 25 March 2024
  • attachments of kinetochores to the microtubules responsible for chromatid separation. Merotelic attachments occur when a single centromere kinetochore attaches...
    12 KB (1,534 words) - 01:12, 29 January 2023
  • Thumbnail for NUF2
    Kinetochore protein Nuf2 is a protein that in humans is encoded by the NUF2 gene. This gene encodes a protein that is highly similar to yeast Nuf2, a...
    8 KB (945 words) - 23:48, 6 April 2024
  • Thumbnail for NSL1
    Kinetochore-associated protein NSL1 homolog is a protein that in humans is encoded by the NSL1 gene. This gene encodes a protein with two coiled-coil...
    5 KB (646 words) - 08:31, 18 August 2023
  • Thumbnail for Cell division
    centrosome to attach to the kinetochores on the sister chromatids. Stable attachment of the spindle apparatus to the kinetochores on the sister chromatids...
    41 KB (4,735 words) - 07:20, 9 October 2024
  • Thumbnail for Strømme syndrome
    in which it forms part of a disc-shaped protein complex known as a kinetochore. CENPF also has a role in orienting long, cylindrical structures called...
    25 KB (2,717 words) - 18:28, 25 March 2024
  • Monopolin receptor and kinetochore protein, DSN1, to bind to and fuse the sister kinetochores. Microtubules can then attach to the kinetochores on the homologous...
    5 KB (310 words) - 08:38, 15 February 2023
  • Thumbnail for Chromosome regions
    certain chromosomes. Named regions include: Arms (p and q) Centromere Kinetochore Telomere Sub telomere satellite chromosome or trabant. NOR region During...
    4 KB (360 words) - 05:08, 28 November 2023
  • yeast strain in which a kinetochore binding protein was missing. The protein was shown to be present at unattached kinetochores and antibody inhibition...
    10 KB (1,150 words) - 15:42, 12 April 2024
  • Thumbnail for Anti-centromere antibodies
    solid, anticentromere) are autoantibodies specific to centromere and kinetochore function. They occur in some autoimmune diseases, frequently in limited...
    3 KB (269 words) - 00:59, 5 February 2024
  • Thumbnail for Protein filament
    Center (MTOC). The positive end of these microtubules will attach to the kinetochore on the chromosome allowing for cellular division when applicable. Nerve...
    14 KB (1,806 words) - 22:50, 17 August 2024