• Thumbnail for Cholinesterase
    The enzyme cholinesterase (EC 3.1.1.8, choline esterase; systematic name acylcholine acylhydrolase) catalyses the hydrolysis of choline-based esters: an...
    17 KB (1,803 words) - 19:04, 26 March 2024
  • Thumbnail for Cholinesterase inhibitor
    Cholinesterase inhibitors (ChEIs), also known as anti-cholinesterase, are chemicals that prevent the breakdown of the neurotransmitter acetylcholine or...
    13 KB (1,105 words) - 12:13, 25 July 2024
  • Thumbnail for Acetylcholinesterase inhibitor
    Acetylcholinesterase inhibitors (AChEIs) also often called cholinesterase inhibitors, inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter...
    26 KB (2,386 words) - 14:39, 28 May 2024
  • are known, such as S1, F1, and F2.[citation needed] Genes encoding cholinesterase 1 (CHE1) and CHE2 have been mapped to 3q26.1-q26.2. One gene is silent...
    13 KB (1,530 words) - 17:29, 7 April 2023
  • Thumbnail for Butyrylcholinesterase
    pseudocholinesterase, or plasma (cholin)esterase, is a nonspecific cholinesterase enzyme that hydrolyses many different choline-based esters. In humans...
    20 KB (2,226 words) - 16:42, 29 May 2024
  • Cholinesterase reactivators are drugs that reverse the inhibition of cholinesterase by organophosphates or sulfonates. They are used as antidote for treating...
    935 bytes (80 words) - 11:35, 29 June 2023
  • Thumbnail for Rivastigmine
    Rivastigmine (sold under the trade name Exelon among others) is a cholinesterase inhibitor used for the treatment of mild to moderate Alzheimer's disease...
    17 KB (1,692 words) - 05:47, 8 August 2024
  • crisis may be masked by the concomitant use of atropine along with cholinesterase inhibitor medication in order to prevent side effects. Flaccid paralysis...
    7 KB (616 words) - 12:40, 22 May 2024
  • Thumbnail for Acetylcholine
    its multi-faceted action (non-selective) and rapid inactivation by cholinesterase. However, it is used in the form of eye drops to cause constriction...
    38 KB (4,232 words) - 12:54, 20 November 2023
  • receptors (thus mimicking acetylcholine), or indirectly by inhibiting cholinesterase, promoting acetylcholine release, or other mechanisms. Common uses of...
    7 KB (618 words) - 06:38, 29 April 2024
  • Thumbnail for Dimethoate
    organophosphates, dimethoate is an acetylcholinesterase inhibitor which disables cholinesterase, an enzyme essential for central nervous system function. It acts both...
    12 KB (1,065 words) - 11:36, 14 June 2024
  • Thumbnail for Suxamethonium chloride
    rapid metabolism of the drug by non-specific plasma cholinesterases. However, plasma cholinesterase activity is reduced in some people due to either genetic...
    26 KB (2,534 words) - 01:00, 8 July 2024
  • Thumbnail for MSPI (nerve agent)
    reactivated by cholinesterase reactivators. EA-2192 Guanitoxin Chabrier, P. E.; Jacob, J. (May 1980). "In vivo and in vitro inhibition of cholinesterase by methyl-1...
    1 KB (77 words) - 23:18, 3 February 2024
  • Thumbnail for Pesticide poisoning
    organophosphate pesticides, it is important to obtain a baseline cholinesterase test. Cholinesterase is an important enzyme of the nervous system, and these chemical...
    37 KB (3,818 words) - 00:14, 18 June 2024
  • administered to humans intravenously, it is capable of inhibiting the plasma cholinesterase (butyrylcholinesterase) enzyme. The dibucaine number is used to differentiate...
    10 KB (1,447 words) - 20:04, 27 December 2023
  • Thumbnail for Donepezil
    and usually improved even with continued use. Donepezil, like other cholinesterase inhibitors, can cause nightmares due to enhanced activation of the visual...
    32 KB (2,823 words) - 20:33, 16 July 2024
  • Thumbnail for Benzgalantamine
    treatment of mild to moderate dementia of the Alzheimer's type. It is a cholinesterase inhibitor. Benzgalantamine is a prodrug of galantamine. The most common...
    6 KB (202 words) - 04:32, 15 August 2024
  • Thumbnail for Vegetable
    nutrients. These include α-solanine, α-chaconine, enzyme inhibitors (of cholinesterase, protease, amylase, etc.), cyanide and cyanide precursors, oxalic acid...
    41 KB (4,011 words) - 02:14, 14 July 2024
  • Thumbnail for Pyridostigmine
    carbamate inhibitor of cholinesterase that does not cross the blood–brain barrier. It carbamylates about 30% of peripheral cholinesterase enzyme, and the carbamylated...
    11 KB (908 words) - 18:20, 2 August 2024
  • agents after surgery. It contains neostigmine as the methylsulfate, a cholinesterase inhibitor, and glycopyrronium bromide, an antimuscarinic agent....
    5 KB (207 words) - 04:58, 26 February 2023
  • Mytelase) is a cholinesterase inhibitor used in the management of myasthenia gravis. It is classified as a reversible cholinesterase inhibitor. Ambenonium...
    4 KB (212 words) - 05:24, 13 February 2023
  • Thumbnail for Echothiophate
    Echothiophate binds irreversibly to cholinesterase. Because of the very slow rate at which echothiophate is hydrolyzed by cholinesterase, its effects can last a week...
    4 KB (271 words) - 19:36, 2 December 2023
  • Thumbnail for Cocaine
    and is extensively metabolized by plasma esterases and also by liver cholinesterases, with only about 1% excreted unchanged in the urine. The metabolism...
    177 KB (18,939 words) - 07:46, 13 August 2024
  • Thumbnail for Drug
    AA Cholinergic Acetylcholine receptor agonist (Muscarinic Nicotinic) Cholinesterase inhibitor Acetylcholine receptor antagonist (Muscarinic Nicotinic (Ganglionic...
    33 KB (3,391 words) - 18:41, 6 August 2024
  • Thumbnail for Antihistamine
    AA Cholinergic Acetylcholine receptor agonist (Muscarinic Nicotinic) Cholinesterase inhibitor Acetylcholine receptor antagonist (Muscarinic Nicotinic (Ganglionic...
    32 KB (3,140 words) - 18:58, 15 July 2024
  • Thumbnail for Assassination of Kim Jong-nam
    low blood levels of cholinesterase, the enzyme inhibited by anticholinesterase agents such as VX. She also stated that cholinesterase levels were within...
    117 KB (11,450 words) - 17:03, 27 July 2024
  • Thumbnail for Bethanechol
    nicotinic receptors. Unlike acetylcholine, bethanechol is not hydrolyzed by cholinesterase and will therefore have a long duration of action. Bethanechol is sold...
    7 KB (390 words) - 21:13, 25 March 2024
  • critically ill individuals. It is unclear if the medication donepezil, a cholinesterase inhibitor, reduces delirium following surgery. There is also no clear...
    100 KB (11,038 words) - 06:51, 12 July 2024
  • The WHO Model List of Essential Medicines (aka Essential Medicines List or EML), published by the World Health Organization (WHO), contains the medications...
    67 KB (4,835 words) - 18:45, 29 July 2024
  • Thumbnail for Enzyme
    8 Acidic Sucrase 6.2 Acidic Catalase 7.0 Neutral Urease 7.0 Neutral Cholinesterase 7.0 Neutral Ribonuclease 7.0–7.5 Neutral Fumarase 7.8 Alkaline Trypsin...
    96 KB (9,819 words) - 12:03, 26 July 2024