CpG oligodeoxynucleotides (or CpG ODN) are short single-stranded synthetic DNA molecules that contain a cytosine triphosphate deoxynucleotide ("C") followed...

pore glass (CPG, see "Solid support material" below), which initiated a massive research effort in solid-phase synthesis of oligonucleotides and eventually...

ASO probes CpG Oligodeoxynucleotide, an ODN with immunostimulatory properties Polypurine reverse-Hoogsteen hairpins, PPRHs, oligonucleotides that can bind...

An anti-sense oligonucleotide (ASO) is a short piece of synthetic DNA complementary to the sequence of a variable target DNA. It acts as a probe for the...

Methylation specific oligonucleotide microarray, also known as MSO microarray, was developed as a technique to map epigenetic methylation changes in DNA...

Arthur M.; Endres, Stefan; Hartmann, Gunther (2001). "Distinct CpG oligonucleotide sequences activate human γ δ T cells via interferon-α/-β". European...

only exception for this global CpG depletion resides in a specific category of GC- and CpG-rich sequences termed CpG islands that are generally unmethylated...

receptor 9 (TLR9) using CpG motif DNA. Later on, he adopted the strategy as a platform for delivery of various oligonucleotide drugs to target oncogenic...

injected directly into a tumor in combination with an unmethylated CpG oligonucleotide, which as a TLR9 ligand activates expression of OX40 so that it can...

analysis of methylation. Oligonucleotide microarrays are designed using pairs of oligonucleotide hybridization probes targeting CpG sites of interest. One...

group of genes or gene clusters, a non-coding region, or a synthetic oligonucleotide such as a primer. Qualitatively, guanine (G) and cytosine (C) undergo...

modification primarily occurs at CpG sites, which in turn tend to cluster in regions called CpG islands. There is a small fraction of CpG islands that can overlap...

target regions of the human genome to measure methylation levels at 27,578 CpG dinucleotides in 14,495 genes. In 2008, Illumina released the Infinium HumanMethylation450...

profiles. It can be applied to large datasets generated using either oligonucleotide arrays (MeDIP-chip) or next-generation sequencing (MeDIP-seq), providing...

which involve the administration of artificial DNA oligonucleotides containing the CpG motif. CpG DNA has applications in treating allergies such as asthma...

guanine, a CpG site. The number of CpG sites in the human genome is about 28 million. Depending on the type of cell, about 70% of the CpG sites have a...

ranging from bacteria to mammals. They are preferentially localized at CpG island promoters in human cells and highly transcribed regions in yeast....

(KAT) uses a modified version of Jellyfish to analyze k-mer counts Oligonucleotide Genomic signature Some of the content in this article was copied from...

tendency of methylated cytosines to cluster at CpG islands (CGIs) to enrich for areas of the genome with a high CpG content. This reduces the cost of sequencing...

use. To improve the delivery issues, chemical modifications, and new oligonucleotide designs have been studied to enhance the drug distribution, side effects...

attention is studies that validated that its gene, EPHX3, was hypermethylated on CpG sites in its Promoter (genetics) in human prostate cancer tissues, particularly...

Cosmids Cot value Cotransduction Cotransformation Coupling Covariance cpDNA CpG island Craniosynostosis Cri du chat cRNA Cross Cross-fertilization Crossbreed...

hypermethylation in cancer cells. It is well known that hypermethylation of CpG-islands in regulatory regions of promoter and/or first exon in a variety...

Andrieu C, Guy C, Copigny F, et al. (September 2007). "High-resolution oligonucleotide array-CGH applied to the detection and characterization of large rearrangements...

Controlled pore glass (CPG) with pore sizes between 50 and 300 nm is also excellently suited for the synthesis of oligonucleotides. In this application...

dehydrogenase - cortisone alpha-reductase - cosmid - costunolide synthase - CpG - craniosynostosis - crp domain - Cu2+-exporting ATPase - cyclodeaminase...

cpDNA See chloroplast DNA. CpG island A region of a genome in which CpG sites occur repetitively or with high frequency. CpG site A sequence of DNA in...

(BNA), morpholino, and peptide nucleic acid (PNA). Although these oligonucleotides have a different backbone sugar—or, in the case of PNA, an amino acid...

this distribution was very similar to genomic distributions of genes and CpG motifs. The distribution of SINEs to genes was significantly more similar...

synthesis of long DNA structures by performing PCR on a pool of long oligonucleotides with short overlapping segments, to assemble two or more pieces of...