• Cryo bio-crystallography is the application of crystallography to biological macromolecules at cryogenic temperatures. Cryo crystallography enables X-ray...
    2 KB (282 words) - 05:57, 24 September 2024
  • Thumbnail for Cryogenic electron microscopy
    giant marine virus (scale bar represents 200 nm) Cryofixation Cryo bio-crystallography Electron tomography (ET) Tivol WF, Briegel A, Jensen GJ (October...
    23 KB (2,518 words) - 06:52, 3 October 2024
  • Thumbnail for Ada Yonath
    drug design. For enabling ribosomal crystallography Yonath introduced a novel technique, cryo bio-crystallography, which became routine in structural...
    23 KB (2,005 words) - 10:56, 21 October 2024
  • properties of molecules for structure determination, including X-ray crystallography, NMR and cryo-EM. Biochemical methods exploit the chemical properties of nucleic...
    35 KB (4,451 words) - 07:28, 9 August 2024
  • Thumbnail for Macromolecular assembly
    biomacromolecular complexes are studied structurally by X-ray crystallography, NMR spectroscopy of proteins, cryo-electron microscopy and successive single particle...
    23 KB (2,293 words) - 16:09, 3 November 2024
  • measurements used in X-ray crystallography. Currently, the 0.143 cutoff is the most commonly used criterion for the resolution of cryo-EM reconstructions better...
    7 KB (784 words) - 17:48, 13 March 2024
  • Thumbnail for Protein
    from synchrotrons. Since then, cryo-electron microscopy (cryo-EM) of large macromolecular assemblies has been developed. Cryo-EM uses protein samples that...
    103 KB (11,472 words) - 16:37, 31 October 2024
  • Thumbnail for Structure validation
    Task Force committees for x-ray crystallography, for NMR, for SAXS (small-angle x-ray scattering), and for cryoEM (cryo-Electron Microscopy). Validations...
    44 KB (4,702 words) - 01:52, 14 August 2024
  • translocon uses BiP. The structure of human Sec61 is resolved at 3.84 Å by cryo-EM in 2020, together with the rest of the co-translational translocon including...
    7 KB (834 words) - 02:43, 29 November 2023
  • of protein crystallography technology. His research focuses on the development of novel methods, such as protein crystallography and cryo-electron microscopy...
    7 KB (689 words) - 14:19, 15 August 2024
  • Thumbnail for Tamir Gonen
    electron cryo-microscopy (cryoEM) particularly in electron crystallography of 2D crystals and for the development of 3D electron crystallography from microscopic...
    12 KB (1,133 words) - 04:15, 30 November 2023
  • Thumbnail for Single particle analysis
    "Automated model building and protein identification in cryo-EM maps". Nature. 628 (8007): 450–457. bioRxiv 10.1101/2023.05.16.541002. doi:10.1038/s41586-024-07215-4...
    22 KB (2,691 words) - 19:21, 30 October 2024
  • Thumbnail for Prion
    highly infectious, brain-derived PrPSc structures have been discovered by cryo-electron microscopy. Another brain-derived fibril structure isolated from...
    99 KB (10,732 words) - 13:28, 2 November 2024
  • Thumbnail for ATP synthase
    currently known at low-resolution from electron cryo-microscopy (cryo-EM) studies of the complex. The cryo-EM model of ATP synthase suggests that the peripheral...
    33 KB (3,752 words) - 14:56, 17 September 2024
  • Thumbnail for Double-stranded RNA viruses
    (MRV), which is the best-studied genotype. Electron cryo-microscopy (cryoEM) and X-ray crystallography have provided a wealth of structural information about...
    17 KB (1,922 words) - 22:37, 6 September 2024
  • Thumbnail for Pamela Bjorkman
    variants arise. The Bjorkman Lab utilizes x-ray crystallography, electron microscopy, electron tomography, cryo-electron microscopy, and fluorescent microscopy...
    13 KB (1,043 words) - 12:48, 25 October 2024
  • Ricardo O. (eds.), "Chapter 10 - Structural biology techniques: X-ray crystallography, cryo-electron microscopy, and small-angle X-ray scattering", Practical...
    20 KB (2,103 words) - 20:12, 3 April 2024
  • Thumbnail for Prokaryotic large ribosomal subunit
    structure and carry out the catalytic functions of the ribosome. X-ray crystallography has yielded electron density maps allowing the structure of the 50S...
    13 KB (1,476 words) - 01:19, 21 April 2024
  • Thumbnail for Ueli Aebi
    microscopy, X-ray crystallography, and protein engineering. Among others, Aebi determined the 3-dimensional structure of the NPC by cryo-electron tomography...
    6 KB (482 words) - 11:35, 16 January 2024
  • Thumbnail for 5S ribosomal RNA
    including immuno-electron microscopy, cryo-electron microscopy, intermolecular chemical cross-linking, and X-ray crystallography, the location of the 5S rRNA within...
    21 KB (2,315 words) - 19:31, 14 July 2024
  • Thumbnail for Epitope mapping
    epitopes on target antigens: X-ray co-crystallography and cryogenic electron microscopy (cryo-EM). X-ray co-crystallography has historically been regarded as...
    23 KB (2,661 words) - 06:50, 2 November 2024
  • can be determined experimentally through techniques such as X-ray crystallography, cryo-electron microscopy and nuclear magnetic resonance, which are all...
    63 KB (5,676 words) - 21:56, 24 October 2024
  • Thumbnail for Ribosome
    determined at 3.5 Å resolution using X-ray crystallography. Then, two weeks later, a structure based on cryo-electron microscopy was published, which depicts...
    65 KB (7,284 words) - 08:11, 23 October 2024
  • Thumbnail for Human papillomavirus infection
    the Royal Society of London. Series B, Biological Sciences. 374 (1773). bioRxiv 10.1101/428912. doi:10.1098/rstb.2018.0303. PMC 6501903. PMID 30955499...
    145 KB (15,967 words) - 01:51, 19 October 2024
  • example, using molecular dynamics in combination with cryo-electron microscopy and X-ray crystallography. to study the structures of large macromolecular complexes...
    26 KB (2,688 words) - 13:40, 3 December 2023
  • Thumbnail for Hemagglutinin
    membrane-distal HA1 and the smaller membrane-proximal HA2. X-ray crystallography, NMR spectroscopy, and cryo-electron microscopy were used to solve the protein's...
    15 KB (1,582 words) - 06:46, 5 August 2024
  • Thumbnail for Bacterial microcompartment
    in Enterohemorrhagic Escherichia coli O157:H7". mBio. 3 (3): e00050–12–e00050–12. doi:10.1128/mBio.00050-12. ISSN 2150-7511. PMC 3372972. PMID 22589288...
    75 KB (8,058 words) - 01:12, 13 October 2024
  • Thumbnail for Carboxysome
    Structurally, carboxysomes are icosahedral, or quasi-icosahedral. Electron cryo-tomography studies have confirmed the approximately icosahedral geometry...
    52 KB (5,224 words) - 16:38, 26 June 2024
  • Thumbnail for Patrick Cramer
    laboratory uses integrated structural biology methods, including X-ray crystallography, cryo-electron microscopy, and biochemical tools. The Cramer laboratory...
    21 KB (2,046 words) - 07:37, 11 April 2024
  • Thumbnail for CCPForge
    Performance Computing in Engineering CCP-BioSim Biomolecular Simulation at the Life Sciences Interface CCP-EM Electron Cryo-Microscopy CCPi Tomographic Imaging...
    5 KB (392 words) - 11:17, 27 January 2024