Cyclic di-GMP (also called cyclic diguanylate and c-di-GMP) is a second messenger used in signal transduction in a wide variety of bacteria. Cyclic di-GMP...
9 KB (935 words) - 06:49, 3 March 2024
cyclic adenosine monophosphate (cAMP), cyclic guanosine monophosphate (cGMP), guanosine pentaphosphate ((p)ppGpp), and cyclic di-GMP (c-di-GMP). c-di-AMP...
18 KB (2,035 words) - 09:25, 25 April 2024
Cyclic di-GMP-I riboswitches are a class of riboswitch that specifically bind cyclic di-GMP, which is a second messenger that is used in a variety of...
6 KB (574 words) - 23:59, 30 June 2024
single molecule: cyclic di-GMP. At low cyclic di-GMP concentration, P. aeruginosa has a free-swimming mode of life. But when cyclic di-GMP levels increase...
92 KB (10,021 words) - 13:15, 15 August 2024
the cyclic dinucleotide cGAMP. Cyclic GMP-AMP (cGAMP) is a cyclic dinucleotide (CDN) and the first to be found in metazoans. Other CDNs (c-di-GMP and...
23 KB (2,886 words) - 00:57, 20 August 2024
Cyclic di-GMP-II riboswitches (also c-di-GMP-II riboswitches) form a class of riboswitches that specifically bind cyclic di-GMP, a second messenger used...
4 KB (386 words) - 23:55, 30 June 2024
Kao CC, Li P (Jul 2012). "Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system". Nature...
23 KB (2,748 words) - 13:53, 21 January 2024
the cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) images, the 'cyclic' portion consists of two bonds between the phosphate...
21 KB (2,416 words) - 10:27, 3 December 2023
diphosphate and one molecule of cyclic di-3’,5’-guanylate (cyclic di-GMP). Degradation of cyclic di-GMP to guanosine monophosphate (GMP) is catalyzed by a phosphodiesterase...
13 KB (1,451 words) - 09:44, 1 August 2024
Cyclic guanosine monophosphate–adenosine monophosphate (cyclic GMP-AMP, cGAMP) is the first cyclic di-nucleotide found in metazoa. In mammalian cells...
7 KB (717 words) - 18:46, 19 February 2023
Cyclic-guanylate-specific phosphodiesterase (EC 3.1.4.52, cyclic bis(3′→5')diguanylate phosphodiesterase, c-di-GMP-specific phosphodiesterase, c-di-GMP...
3 KB (308 words) - 22:55, 29 March 2024
(see also "cyclic di-GMP" below). cyclic di-AMP riboswitches (also called ydaO/yuaA) bind the signaling molecule cyclic di-AMP. cyclic di-GMP riboswitches...
36 KB (3,891 words) - 23:57, 30 June 2024
Histidine Kinase (SHK) Family TC# 9.B.34 - The Kinase/Phosphatase/Cyclic-GMP Synthase/Cyclic di-GMP Hydrolase (KPSH) Family The first identified substrates for...
3 KB (460 words) - 11:37, 23 September 2019
models, such as 4hg6, follow similarly.) The enzyme is stimulated by cyclic di-GMP. In vivo but not in vitro, a third subunit called BcsC made up of a...
22 KB (2,529 words) - 08:38, 27 August 2024
PilZ is a c-di-GMP binding domain and PilZ domain-containing proteins represent the best studied class of c-di-GMP effectors. C-di-GMP, cyclic diguanosine...
5 KB (635 words) - 15:27, 30 January 2024
function can be the result of a combination of the binding of cyclic nucleotides (cGMP and cAMP) and either a depolarization or a hyperpolarization event...
39 KB (4,913 words) - 23:11, 11 January 2024
are located upstream of rpfG genes, which likely function as part of cyclic di-GMP signaling by degrading this molecule. This observation might suggest...
1 KB (109 words) - 20:42, 7 December 2021
reductase domains, proteins in the major facilitator superfamily and cyclic di-GMP-specific phosphodiesterases of the EAL family. It was therefore proposed...
2 KB (155 words) - 20:46, 7 December 2021
domain. Its function is to act as a diguanylate cyclase and synthesize cyclic di-GMP, which is used as an intracellular signalling molecule in a wide variety...
3 KB (270 words) - 05:57, 30 August 2021
discovery of a new signalling network, which is based on the cyclic di-nucleotide (c-di-GMP) and which coordinates bacterial surface colonization and virulence...
8 KB (690 words) - 13:09, 12 September 2023
Bacteriophytochrome Mediates Interplay between Light Sensing and the Second Messenger Cyclic Di-GMP to Control Social Behavior and Virulence". Cell Reports. 32 (13): 108202...
6 KB (721 words) - 18:50, 30 January 2024
between both the motile and sessile phases, a process regulated by cyclic-di-GMP. On top of that, C. difficile is capable of forming biofilms and cell-to-cell...
54 KB (5,746 words) - 03:44, 10 July 2024
biomolecules, e.g. acyl carrier proteins, phospholipids and the cyclic forms of GMP and AMP (cGMP and cAMP). Phosphodiester bonds make up the backbones of DNA...
5 KB (581 words) - 01:37, 14 August 2024
site Nuclear introns Group II intron Group III intron Twintron LtrA Cyclic di-GMP-II riboswitch, where there is an example of a riboswitch acting together...
13 KB (1,540 words) - 22:36, 3 August 2024
drive evolution of pro-biofilm variants in pathogens by modulating cyclic-di-GMP levels". Open Biology. 6 (11): 160162. doi:10.1098/rsob.160162. PMC 5133437...
47 KB (5,366 words) - 04:45, 25 June 2024
allowed to reach to the bacterial cells may be dangerous for the cells. Cyclic-di-GMP signaling had also been involved in the regulation of antimicrobial...
61 KB (6,549 words) - 21:38, 28 August 2024
cis regulator. However, since some known cis-regulatory RNAs, e.g., cyclic di-GMP riboswitches do control a wide variety of genes, it is possibility that...
3 KB (302 words) - 06:53, 20 April 2022
studying the mechanisms of signal transduction of the messenger substrate cyclic di-GMP and the structure-function relationships of bacterial effector proteins...
4 KB (292 words) - 23:19, 12 January 2023
the intracellular second messengers, cyclic adenosine monophosphate (cAMP) and cyclic guanosine monophosphate (cGMP) by the respective PDE subtype(s). The...
22 KB (2,350 words) - 08:18, 3 June 2024
Jeffrey A.; Boon, Elizabeth M. (2012). "Nitric Oxide Regulation of Cyclic di-GMP Synthesis and Hydrolysis inShewanella woodyi". Biochemistry. 51 (10):...
2 KB (226 words) - 01:25, 2 September 2023