Cyclin-dependent kinase 1 also known as CDK1 or cell division cycle protein 2 homolog is a highly conserved protein that functions as a serine/threonine...
24 KB (2,875 words) - 23:48, 3 December 2023
Cyclin-dependent kinases (CDKs) are a predominant group of serine/threonine protein kinases involved in the regulation of the cell cycle and its progression...
35 KB (3,829 words) - 14:24, 17 June 2024
Cyclin-dependent kinase 4 also known as cell division protein kinase 4 is an enzyme that in humans is encoded by the CDK4 gene. CDK4 is a member of the...
21 KB (2,372 words) - 12:19, 28 July 2024
Cyclin-dependent kinase 2, also known as cell division protein kinase 2, or Cdk2, is an enzyme that in humans is encoded by the CDK2 gene. The protein...
35 KB (4,314 words) - 00:26, 6 July 2024
kinase 6 (CDK6) is an enzyme encoded by the CDK6 gene. It is regulated by cyclins, more specifically by Cyclin D proteins and Cyclin-dependent kinase...
35 KB (4,042 words) - 05:00, 1 April 2024
Cyclin-dependent kinase 5 is a protein, and more specifically an enzyme, that is encoded by the Cdk5 gene. It was discovered 15 years ago, and it is saliently...
42 KB (5,356 words) - 07:42, 8 May 2024
Cyclin-dependent kinase 9 or CDK9 is a cyclin-dependent kinase associated with P-TEFb. The protein encoded by this gene is a member of the cyclin-dependent...
12 KB (1,460 words) - 23:03, 27 March 2024
A cyclin-dependent kinase inhibitor protein (also known as CKIs, CDIs, or CDKIs) is a protein that inhibits the enzyme cyclin-dependent kinase (CDK) and...
10 KB (1,169 words) - 17:52, 15 August 2024
subunit of a protein kinase, cyclin-dependent kinase (CDK), with a regulatory subunit, cyclin. Once cyclin-dependent kinases bind to cyclin, the formed complex...
18 KB (2,258 words) - 22:16, 16 December 2023
Cyclin-dependent kinase 7, or cell division protein kinase 7, is an enzyme that in humans is encoded by the CDK7 gene. The protein encoded by this gene...
20 KB (2,347 words) - 23:01, 27 March 2024
kinase 8 is an enzyme that in humans is encoded by the CDK8 gene. The protein encoded by this gene is a member of the cyclin-dependent protein kinase...
21 KB (2,557 words) - 01:16, 24 April 2022
Cyclin-dependent kinase inhibitor 1C (p57, Kip2), also known as CDKN1C, is a protein which in humans is encoded by the CDKN1C imprinted gene. Cyclin-dependent...
17 KB (2,000 words) - 14:41, 9 February 2024
protein kinases". EMBO J. 11 (8): 2909–17. doi:10.1002/j.1460-2075.1992.tb05360.x. PMC 556772. PMID 1639063. "Entrez Gene: CDK3 cyclin-dependent kinase 3"...
7 KB (771 words) - 19:05, 28 December 2023
Cyclin dependent kinase like 1 is a protein that in humans is encoded by the CDKL1 gene. This gene product is a member of a large family of CDC2-related...
1 KB (169 words) - 11:03, 30 September 2023
proteins that form holoenzymes with cyclin-dependent protein kinases (Cdk), which they activate. The abundance of cyclins is generally regulated by protein...
39 KB (4,605 words) - 22:37, 27 March 2024
of which contain multiple non-AUG translation initiation sites. Cyclin-dependent kinase 10 has been shown to interact with ETS2. GRCh38: Ensembl release...
6 KB (729 words) - 22:29, 2 January 2024
CDKN2A (redirect from Cyclin-dependent kinase inhibitor 2A)
CDKN2A, also known as cyclin-dependent kinase inhibitor 2A, is a gene which in humans is located at chromosome 9, band p21.3. It is ubiquitously expressed...
26 KB (3,317 words) - 18:16, 27 April 2024
"nuclear clock." MPF is composed of two subunits: Cyclin-dependent kinase 1 (CDK1), the cyclin-dependent kinase subunit. It uses ATP to phosphorylate specific...
6 KB (873 words) - 07:41, 3 June 2024
Cyclins are proteins that control the progression of a cell through the cell cycle by activating cyclin-dependent kinases (CDK). Cyclins were originally...
19 KB (1,760 words) - 11:01, 23 August 2024
cyclin-dependent kinase regulatory subunit family is a family of proteins consisting of the regulatory subunits of cyclin-dependent protein kinases....
3 KB (318 words) - 13:13, 13 February 2024
biochemistry, PDPK1 refers to the protein 3-phosphoinositide-dependent protein kinase-1, an enzyme which is encoded by the PDPK1 gene in humans. It is...
18 KB (2,127 words) - 19:11, 8 April 2024
In cell biology, protein kinase A (PKA) is a family of serine-threonine kinase whose activity is dependent on cellular levels of cyclic AMP (cAMP). PKA...
27 KB (2,665 words) - 17:03, 6 April 2024
(CDK/MAPK/GSK3/CLK) kinase group. The closest relatives of MAPKs are the cyclin-dependent kinases (CDKs). The first mitogen-activated protein kinase to be discovered...
46 KB (5,492 words) - 14:52, 20 August 2024
cell cycle. Cyclins function as regulators of CDKs (cyclin-dependent kinase). Different cyclins exhibit distinct expression and degradation patterns...
49 KB (5,694 words) - 22:42, 27 March 2024
P21 (section p53 dependent response)
(alternatively p21Waf1), also known as cyclin-dependent kinase inhibitor 1 or CDK-interacting protein 1, is a cyclin-dependent kinase inhibitor (CKI) that is capable...
34 KB (3,978 words) - 08:00, 23 February 2024
media related to Kinases. Activation loop Autophosphorylation Ca2+/calmodulin-dependent protein kinase Cell signaling Cyclin-dependent kinase G protein-coupled...
34 KB (3,807 words) - 19:38, 18 August 2024
breast cancer. Cyclin D3 has been shown to interact with: AKAP8, CDC2L1, CDKN1B, CRABP2, Cyclin-dependent kinase 4, Cyclin-dependent kinase 6, EIF3K, and...
14 KB (1,604 words) - 22:42, 25 May 2024
CAMK (redirect from Calcium/calmodulin-dependent protein kinase II)
written as CaMK or CCaMK, is an abbreviation for the Ca2+/calmodulin-dependent protein kinase class of enzymes. CAMKs are activated by increases in the concentration...
8 KB (886 words) - 12:46, 31 January 2024
cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDKs) through conformational...
8 KB (1,042 words) - 23:25, 3 January 2024
gene CDKL5. This gene provides instructions for making a protein (cyclin-dependent kinase-like 5) that is essential for normal brain development and function...
25 KB (2,458 words) - 08:29, 3 July 2024