• Thumbnail for Cyclin A1
    Cyclin-A1 is a protein that in humans is encoded by the CCNA1 gene. The protein encoded by this gene belongs to the highly conserved cyclin family, whose...
    11 KB (1,435 words) - 20:58, 22 December 2023
  • Thumbnail for Cyclin-dependent kinase 2
    Cyclin-dependent kinase 2, also known as cell division protein kinase 2, or Cdk2, is an enzyme that in humans is encoded by the CDK2 gene. The protein...
    35 KB (4,314 words) - 00:26, 6 July 2024
  • Thumbnail for Cyclin A2
    Cyclin-A2 is a protein that in humans is encoded by the CCNA2 gene. It is one of the two types of cyclin A: cyclin A1 is expressed during meiosis and...
    21 KB (2,580 words) - 03:53, 26 August 2024
  • form. Cyclin A1 is prevalently expressed during meiosis and early on in embryogenesis. Cyclin A2 is expressed in dividing somatic cells. Cyclin A, along...
    14 KB (1,753 words) - 03:43, 26 August 2024
  • Thumbnail for Inhibitor of cdk, cyclin a1 interacting protein 1
    Inhibitor of CDK, cyclin A1 interacting protein 1 is a protein that in humans is encoded by the INCA1 gene. GRCh38: Ensembl release 89: ENSG00000196388...
    1,011 bytes (149 words) - 17:45, 8 November 2024
  • beta A1 Cyclic nucleotide-gated channel alpha 1 Cyclin A1 Cytochrome P450, family 1, member A1 Defensin, alpha 1 Dystrophin-associated protein A1 Ephrin...
    5 KB (667 words) - 18:06, 14 March 2022
  • Thumbnail for Retinoblastoma protein
    ARID4A Aryl hydrocarbon receptor BRCA1 BRF1 C-jun C-Raf CDK9 CUTL1 Cyclin A1 Cyclin D1 Cyclin T2 DNMT1 E2F1 E2F2, E4F1 EID1 ENC1 FRK HBP1 HDAC1 HDAC3 Histone...
    79 KB (9,502 words) - 07:42, 4 September 2024
  • Thumbnail for P16
    p16 (also known as p16INK4a, cyclin-dependent kinase inhibitor 2A, CDKN2A, multiple tumor suppressor 1 and numerous other synonyms), is a protein that...
    37 KB (4,271 words) - 15:30, 14 June 2024
  • Thumbnail for Chromosome 17
    inducible domain family member 1B INCA1: encoding protein Inhibitor of cdk, cyclin a1 interacting protein 1 JPT1: encoding protein Jupiter microtubule associated...
    28 KB (2,133 words) - 22:16, 24 December 2024
  • Thumbnail for Cyclin B3
    G2/mitotic-specific cyclin-B3 is a protein encoded by the CCNB3 gene located on the X chromosome in humans. Cyclin B3 has features of both A type cyclins and B type...
    16 KB (1,888 words) - 15:35, 30 December 2024
  • Thumbnail for MYBL2
    MYBL2 has been shown to interact with: CDK9 CREB-binding protein Cyclin A1 Cyclin-dependent kinase inhibitor 1C EP300 PARP1 Retinoblastoma-like protein...
    13 KB (1,486 words) - 15:26, 22 August 2024
  • Thumbnail for Cytoglobin
    Risk JM (Feb 2006). "Promoter methylation of P16, RARbeta, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing"...
    13 KB (1,486 words) - 21:07, 6 December 2024
  • Thumbnail for E2F1
    promoter[PAX8] => E2F1 E2F1 has been shown to interact with: ARID3A, CUL1, Cyclin A1, Cyclin A2, GTF2H1, MDM4, NCOA6, NDN, NPDC1, PURA, PHB, RB1, UDG, RBL1, SKP2...
    16 KB (1,875 words) - 09:14, 29 March 2024
  • Thumbnail for Receptor for activated C kinase 1
    has been shown to interact with: AGTRAP Androgen receptor, CD18, CD29 Cyclin A1 EIF6, FYN, IFNAR2, Janus kinase 1 OTUB1, P73, PDE4D, PRKCB1, PRKCE, PTPRM...
    22 KB (2,598 words) - 10:03, 11 April 2024
  • by the absence of cyclin E1 and/or the inhibition of the cyclin-E1–CDK2 complex by p21, p27, and p53. Next, the absence of cyclin A1 commits the neuron...
    12 KB (1,732 words) - 19:27, 30 October 2024
  • Specifically, miR-427 targets include cell cycle regulators such as Cyclin A1 and Cyclin B2. Lee MT, Bonneau AR, Takacs CM, Bazzini AA, DiVito KR, Fleming...
    10 KB (1,215 words) - 01:06, 25 October 2024
  • Thumbnail for GPS2 (gene)
    protein 1) function. GPS2 (gene) has been shown to interact with: C21orf7, Cyclin A1, EP300, HDAC3, NCOR1, P53, and TBL1X. GRCh38: Ensembl release 89: ENSG00000132522...
    10 KB (1,333 words) - 20:36, 13 October 2022
  • Thumbnail for CDC20
    below). CDC20 has been shown to interact with: ANAPC7 BUB1B, CDC16, CDC27, Cyclin A1, FBXO5, HDAC1, HDAC2, and MAD2L1. However, the most important interaction...
    26 KB (3,307 words) - 16:24, 13 October 2024
  • Thumbnail for OCEL1
    Leukemia Cell Proliferation by Phosphorylating Acinus and Regulating Cyclin A1". Cancer Research. 68 (12): 4559–4570. doi:10.1158/0008-5472.can-08-0021...
    14 KB (1,572 words) - 02:17, 28 March 2024
  • Thumbnail for Cell division
    controlled by cyclin and cyclin-dependent kinases. The progression of interphase is the result of the increased amount of cyclin. As the amount of cyclin increases...
    41 KB (4,735 words) - 04:45, 17 December 2024
  • Thumbnail for RBM4
    engages in interactions with cyclin A1 and undergoes phosphorylation by cyclin A1–CDK2. The levels of RBM4 and cyclin A1 exhibit a correlation in normal...
    19 KB (2,376 words) - 10:41, 11 April 2024
  • Thumbnail for Cyclin-dependent kinase 6
    encoded by the CDK6 gene. It is regulated by cyclins, more specifically by Cyclin D proteins and Cyclin-dependent kinase inhibitor proteins. The protein...
    35 KB (4,042 words) - 05:00, 1 April 2024
  • Thumbnail for Retinoblastoma-like protein 2
    Retinoblastoma-like protein 2 has been shown to interact with: BRCA1, BRF1 C-Raf, Cyclin E1, Cyclin-dependent kinase 2, HDAC1, Prohibitin, and RBBP8. Pocket protein family...
    12 KB (1,534 words) - 09:05, 4 January 2024
  • Thumbnail for ARID2
    2004). "Identification of interaction partners and substrates of the cyclin A1-CDK2 complex". The Journal of Biological Chemistry. 279 (32): 33727–41...
    8 KB (1,027 words) - 06:54, 18 December 2023
  • Thumbnail for Homeobox protein SIX1
    2004). "The Six1 homeoprotein stimulates tumorigenesis by reactivation of cyclin A1". Proceedings of the National Academy of Sciences of the United States...
    11 KB (1,387 words) - 06:32, 15 August 2023
  • the molecular mechanisms of sleep. Rogulja found that cyclin A (CycA) and its regulator cyclin A1 promote sleep in Drosophila. Fascinatingly, CycA is only...
    16 KB (1,872 words) - 08:26, 3 January 2023
  • Thumbnail for Meiosis
    WEE1 as well as regulation of cyclin B levels facilitated by the anaphase-promoting complex (APC). CDK1 is regulated by cyclin B, whose synthesis peaks at...
    76 KB (8,952 words) - 05:29, 19 December 2024
  • Thumbnail for CCNY (gene)
    Cyclin-Y is a protein that in humans is encoded by the CCNY gene. GRCh38: Ensembl release 89: ENSG00000108100 – Ensembl, May 2017 GRCm38: Ensembl release...
    3 KB (399 words) - 14:15, 25 March 2024
  • Thumbnail for P-TEFb
    Drosophila cells. It is a cyclin dependent kinase containing the catalytic subunit, Cdk9, and a regulatory subunit, cyclin T in Drosophila. In humans...
    10 KB (1,397 words) - 12:01, 17 October 2024
  • Thumbnail for 7SK RNA
    P-TEFb was a component of the complex. 7SK associates with and inhibits the cyclin dependent kinase activity of P-TEFb through the action of the RNA binding...
    10 KB (1,102 words) - 05:38, 18 August 2021