DNA polymerase IV is a prokaryotic polymerase that is involved in mutagenesis and is encoded by the dinB gene. It exhibits no 3′→5′ exonuclease (proofreading)...
5 KB (559 words) - 03:25, 13 March 2023
A DNA polymerase is a member of a family of enzymes that catalyze the synthesis of DNA molecules from nucleoside triphosphates, the molecular precursors...
59 KB (7,090 words) - 06:49, 30 June 2024
DNA polymerase II (also known as DNA Pol II or Pol II) is a prokaryotic DNA-dependent DNA polymerase encoded by the PolB gene. DNA Polymerase II is an...
19 KB (2,328 words) - 05:16, 22 August 2024
DNA polymerase III holoenzyme is the primary enzyme complex involved in prokaryotic DNA replication. It was discovered by Thomas Kornberg (son of Arthur...
7 KB (807 words) - 13:43, 10 December 2023
DNA polymerase IV (DinB) and DNA polymerase V (UmuD'2C) - SOS repair polymerases; Pol η, ι, κ Reverse transcriptase (RT; RNA-directed DNA polymerase;...
7 KB (673 words) - 23:08, 9 July 2024
DNA polymerase I (or Pol I) is an enzyme that participates in the process of prokaryotic DNA replication. Discovered by Arthur Kornberg in 1956, it was...
15 KB (1,871 words) - 06:15, 30 May 2024
DNA polymerase may refer to: DNA polymerase, enzymes that create DNA molecules by assembling nucleotides DNA polymerase I, an enzyme that participates...
1 KB (209 words) - 23:59, 2 April 2016
In molecular biology, RNA polymerase (abbreviated RNAP or RNApol), or more specifically DNA-directed/dependent RNA polymerase (DdRP), is an enzyme that...
43 KB (5,109 words) - 08:28, 28 October 2024
of the DNA polymerase III holoenzyme, the clamp protein binds DNA polymerase and prevents this enzyme from dissociating from the template DNA strand....
23 KB (2,044 words) - 07:04, 10 March 2024
switching out regular DNA polymerases for specialized translesion polymerases (i.e. DNA polymerase IV or V, from the Y Polymerase family), often with larger...
129 KB (15,900 words) - 22:25, 12 October 2024
DNA polymerase mu is a polymerase enzyme found in eukaryotes. In humans, this protein is encoded by the POLM gene. Pol μ is a member of the X family of...
5 KB (702 words) - 16:04, 3 December 2023
known as RNA Polymerases, which synthesize RNA from DNA templates. Discovered via phylogenetic studies of land plants, genes of RNAP IV are thought to...
15 KB (1,821 words) - 09:09, 14 August 2023
gyrase and topoisomerase IV remove the positive supercoils that accumulate ahead of a translocating DNA polymerase, allowing DNA replication to continue...
3 KB (375 words) - 21:08, 29 March 2021
Terminal deoxynucleotidyl transferase (redirect from DNA nucleotidylexotransferase)
transferase (TdT), also known as DNA nucleotidylexotransferase (DNTT) or terminal transferase, is a specialized DNA polymerase expressed in immature, pre-B...
30 KB (3,557 words) - 05:39, 17 August 2024
in an ATP dependent manner while double-stranded DNA is being unwound by elongating RNA-polymerase or by helicase in front of the progressing replication...
15 KB (1,871 words) - 08:04, 9 August 2024
Dicer and RNA-dependent RNA polymerase proteins. RdDM has been implicated in a number of regulatory processes in plants. The DNA methylation added by RdDM...
139 KB (14,822 words) - 02:25, 16 July 2024
POLK (redirect from DNA polymerase kappa)
DNA polymerase kappa is a DNA polymerase that in humans is encoded by the POLK gene. It is involved in translesion synthesis. GRCh38: Ensembl release 89:...
7 KB (928 words) - 02:00, 23 December 2023
Exonuclease (section Significance to polymerase)
the polymerase. This process involves the exonuclease's catching up to the pol II and terminating the transcription. Pol I then synthesizes DNA nucleotides...
14 KB (1,752 words) - 22:37, 2 October 2024
subunit of DNA polymerase III in environments of varying salt concentrations. In DNA replication at the lagging strand site, DNA polymerase III removes...
19 KB (2,263 words) - 01:58, 11 December 2023
in repairing single-strand breaks in duplex DNA in living organisms, but some forms (such as DNA ligase IV) may specifically repair double-strand breaks...
23 KB (2,787 words) - 00:53, 18 June 2024
Topoisomerase (redirect from Dna topoisomerases)
of the DNA duplex during DNA replication and transcription. If left unchanged, this torsion would eventually stop the DNA or RNA polymerases involved...
57 KB (6,173 words) - 00:11, 11 December 2023
core enzymes – a recombinase, a single-stranded DNA-binding protein (SSB) and strand-displacing polymerase. Recombinases are capable of pairing oligonucleotide...
14 KB (1,707 words) - 15:45, 22 October 2024
Circular chromosome (redirect from Bacterial DNA)
Primase (DnaG protein). Deoxynucleotides are then added to this primer by a single DNA polymerase III dimer, in an integrated complex with DnaB helicase...
21 KB (2,745 words) - 15:34, 29 June 2024
required for DNA/RNA synthesis. Because DNA must be unwound for DNA/RNA polymerase action, supercoils will result. The region ahead of the polymerase complex...
32 KB (4,316 words) - 08:47, 15 August 2024
Operon (redirect from DNA operator)
which provides a site for RNA polymerase to bind and initiate transcription. Close to the promoter lies a section of DNA called an operator. All the structural...
21 KB (2,544 words) - 00:40, 27 April 2024
Base excision repair (redirect from Base excision DNA repair)
occur before DNA synthesis can initiate because DNA polymerases require a 3' hydroxyl to extend from. Pol β is the main human polymerase that catalyzes...
29 KB (3,493 words) - 23:41, 26 October 2024
DNA polymerase makes an error resulting in a mismatched base-pair or a small insertion or deletion during DNA synthesis, the cell will repair the DNA...
16 KB (1,844 words) - 17:37, 28 November 2023
Molecular cloning (redirect from Recombinant DNA technology)
Polymerase chain reaction (PCR) methods are often used for amplification of specific DNA or RNA (RT-PCR) sequences prior to molecular cloning. DNA for...
32 KB (4,016 words) - 17:56, 20 August 2024
(siRNA). Together with RNA polymerase IV (Pol IV), Pol V is involved in an siRNA-dependent epigenetic pathway known as RNA-directed DNA methylation (RdDM), which...
4 KB (604 words) - 12:45, 22 February 2024
Non-homologous end joining (category DNA repair)
terminus used to initiate DNA synthesis is less stable at 3' overhangs, necessitating a specialized NHEJ polymerase. The DNA ligase IV complex, consisting of...
28 KB (3,683 words) - 16:38, 29 October 2024