Dabigatran, sold under the brand name Pradaxa among others, is an anticoagulant used to treat and prevent blood clots and to prevent stroke in people with...
41 KB (3,748 words) - 03:02, 10 December 2024
US FDA in 2015, that reverses the effect of dabigatran by binding to both free and thrombin-bound dabigatran. Andexanet alfa is a recombinant modified human...
78 KB (8,755 words) - 07:51, 27 October 2024
name Praxbind, is a monoclonal antibody used as a reversal agent for dabigatran. Idarucizumab was developed by Boehringer Ingelheim. One study sponsored...
11 KB (806 words) - 05:38, 27 May 2024
(pramipexole) Ofev / Vargatef (Nintedanib) Mobic / Movalis (meloxicam) Pradaxa (dabigatran etexilate) Spiriva (tiotropium bromide) Trajenta / Tradjenta (linagliptin)...
40 KB (3,323 words) - 11:47, 26 November 2024
Unfractionated heparin (w/ warfarin) LMWH/Low molecular weight heparin Dabigatran Direct Factor Xa Inhibitors Graduated compressed stocking High degree...
10 KB (1,049 words) - 04:14, 19 October 2024
Other drugs with adverse reactions include dabigatran etexilate, lamivudine, and vincristine. Dabigatran etexilate used with p-glycoprotein inducers...
29 KB (2,369 words) - 15:54, 16 November 2024
INR of 2-3) or one of the direct oral anticoagulant drugs (DOACs, e.g. dabigatran, rivaroxaban, edoxaban, or apixaban) is recommended. If the patient is...
30 KB (2,888 words) - 17:25, 11 November 2024
knowledge of NAPAP to develop DTIs. Dabigatran, like NAPAP binds to S1, S2 and S4 pockets. Benzamidine group on the dabigatran structure binds deep in the S1...
33 KB (3,756 words) - 17:07, 14 December 2023
including factor Xa inhibitors (rivaroxaban, apixaban and edoxaban), dabigatran, and heparins (including fondaparinux, low molecular weight heparins (LMWH)...
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diabetes, or symptomatic heart failure. Apixaban and other anticoagulants (dabigatran, edoxaban and rivaroxaban) appear equally effective as warfarin in preventing...
25 KB (2,072 words) - 19:30, 7 December 2024
already in clinical use (such as lepirudin, argatroban, bivalirudin and dabigatran). Also in clinical use are other small molecular compounds that interfere...
64 KB (6,553 words) - 00:22, 16 December 2024
10 but there is no active bleeding. The newer anticoagulants apixaban, dabigatran and rivaroxaban are not vitamin K antagonists. Coumarin is used in the...
69 KB (7,757 words) - 14:42, 24 September 2024
treatment used. Oral anticoagulants, especially Xa (apixaban) and thrombin (dabigatran) inhibitors, have been shown to be superior to warfarin in stroke reduction...
187 KB (20,646 words) - 11:42, 22 December 2024
treatment, whereas dabigatran and edoxaban do. A Cochrane review found that there is no evidence of a difference between oral DTIs (dabigatran, rivaroxaban...
87 KB (9,764 words) - 15:58, 17 December 2024
2015 and six in 2017. Examples of recently approved prodrugs are such as dabigatran etexilate (approved in 2010), gabapentin enacarbil (2011), sofosbuvir...
12 KB (1,285 words) - 05:41, 9 December 2024
because it prevents thrombus extension. The anti-coagulation medications dabigatran and rivaroxaban decrease D-dimer levels but do not interfere with the...
20 KB (2,204 words) - 10:47, 16 December 2024
acid Hydroxocobalamin Complementary: Erythropoiesis-stimulating agentsα Dabigatran Enoxaparin Heparin sodium Phytomenadione Protamine sulfate Tranexamic...
67 KB (4,835 words) - 02:06, 4 December 2024
include: Argatroban Inogatran Melagatran (and its prodrug ximelagatran) Dabigatran Thrombin demonstrates a high level of allosteric regulation. Allosterism...
7 KB (821 words) - 09:44, 30 January 2023
other newer generation anticoagulants such as edoxaban, apixaban, and dabigatran as well as with the generic anticoagulant warfarin. It has similar efficacy...
121 KB (11,533 words) - 10:41, 15 December 2024
20 April 2014. Moore T. "Monitoring FDA MedWatch Reports: Signals for Dabigatran and Metoclopramide" (PDF). QuarterWatch. Institute for Safe Medication...
36 KB (3,364 words) - 14:30, 17 December 2024
Carbon monoxide poisoning and cyanide poisoning Idarucizumab Reversal of dabigatran etexilate, an anticoagulant Insulin + Glucagon Beta blocker poisoning...
8 KB (523 words) - 11:51, 18 May 2024
which contain a benzimidazole group include abemaciclib, bendamustine, dabigatran, daridorexant, and glasdegib. In printed circuit board manufacturing,...
9 KB (721 words) - 13:33, 3 September 2024
offering the efficacy of warfarin without a need for monitoring, such as dabigatran, apixaban, edoxaban, and rivaroxaban, have been approved in a number of...
94 KB (9,796 words) - 09:56, 4 November 2024
ciclosporin, antiplatelet drugs like clopidogrel, anticoagulants like dabigatran or warfarin, or NSAIDs such as aspirin, celecoxib, or ibuprofen. Prolonged...
44 KB (3,621 words) - 09:11, 17 December 2024
PMID 34703341. DeDea L (January 2011). "The difference between Tdap and DTaP; dabigatran versus warfarin". JAAPA. 24 (1): 14. doi:10.1097/01720610-201101000-00002...
72 KB (6,125 words) - 19:27, 26 November 2024
Anticoagulation can be achieved through several means including warfarin, heparin, dabigatran, rivaroxaban, edoxaban, and apixaban. Many issues should be considered...
153 KB (17,044 words) - 04:14, 12 December 2024
antithrombin III. The drug is not effective against factor IIa inhibitor dabigatran. Its activity is measured using the anti-Xa test, which is utilized to...
16 KB (1,367 words) - 13:26, 14 October 2024
apixaban, but is very sensitive to direct thrombin inhibitors including dabigatran, argatroban, and bivalirudin. After separating the plasma from the whole...
7 KB (742 words) - 23:19, 23 November 2024
that is widely used for lupus anticoagulant testing in certain regions. Dabigatran etexilate is a direct oral thrombin inhibitor that has been approved as...
9 KB (1,177 words) - 01:04, 3 February 2024
Terleira-Fernández AI, Calvo-Rojas G, Suárez-Gea ML, Vargas-Castrillón E (2013). "Dabigatran, Rivaroxaban, or Apixaban versus Warfarin in Patients with Nonvalvular...
29 KB (2,612 words) - 03:54, 20 November 2024