• Thumbnail for Deoxycytidine triphosphate
    Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that contains the pyrimidine base cytosine. The triphosphate group contains high-energy...
    3 KB (139 words) - 18:28, 30 April 2023
  • Thumbnail for Deoxycytidine diphosphate
    Deoxycytidine diphosphate is a nucleoside diphosphate. It is related to the common nucleic acid CTP, or cytidine triphosphate, with the -OH (hydroxyl)...
    4 KB (260 words) - 17:14, 18 July 2024
  • Thumbnail for Deoxycytidine kinase
    Deoxycytidine kinase (dCK) is an enzyme which is encoded by the DCK gene in humans. dCK predominantly phosphorylates deoxycytidine (dC) and converts dC...
    21 KB (2,519 words) - 01:02, 3 December 2023
  • nucleoside diphosphate kinase can phosphorylate into cytidine triphosphate or deoxycytidine triphosphate. Phosphoribosyltransferases add activated ribose-5-phosphate...
    7 KB (736 words) - 10:22, 12 August 2024
  • Thumbnail for Deoxyadenosine triphosphate
    triphosphate (dATP) is a nucleotide used in cells for DNA synthesis (or replication), as a substrate of DNA polymerase. Deoxyadenosine triphosphate is...
    8 KB (653 words) - 16:18, 4 September 2023
  • Thumbnail for Gemcitabine
    active as gemcitabine triphosphate (dFdCTP). After being thrice phosphorylated, gemcitabine can masquerade as deoxycytidine triphosphate and is incorporated...
    26 KB (2,420 words) - 15:49, 26 June 2024
  • deoxynucleotide concentrations, including deoxycytidine triphosphate. Gemcitabine triphosphate competes with deoxycytidine triphosphate for incorporation into DNA....
    60 KB (6,590 words) - 06:01, 15 September 2024
  • Thumbnail for Azacitidine
    azacitidine have been metabolized to 5-aza-2′-deoxycytidine-triphosphate (aka, decitabine-triphosphate), they can be incorporated into DNA and azacytosine...
    20 KB (1,915 words) - 00:12, 31 March 2024
  • polymerase and "rotating the template guanine," which prevents deoxycytidine triphosphate (dCTP) from binding. This S phase block induces apoptosis in HeLa...
    27 KB (3,275 words) - 08:57, 2 November 2024
  • Thumbnail for Cytidine monophosphate
    adenosine triphosphate or guanosine triphosphate donating the phosphate group. Since cytidine triphosphate is generated by amination of uridine triphosphate, the...
    3 KB (144 words) - 17:01, 30 April 2023
  • class is dCTP aminohydrolase. Other names in common use include deoxycytidine triphosphate deaminase, and 5-methyl-dCTP deaminase. This enzyme participates...
    2 KB (164 words) - 13:44, 26 August 2023
  • Thumbnail for Arabinofuranosylcytosine triphosphate
    Arabinofuranosylcytosine triphosphate is a nucleotide that inhibits the synthesis of DNA by acting as an antimetabolic agent against deoxycytidine (a component of...
    2 KB (39 words) - 02:52, 29 April 2023
  • Thumbnail for DNA polymerase
    enzymes that catalyze the synthesis of DNA molecules from nucleoside triphosphates, the molecular precursors of DNA. These enzymes are essential for DNA...
    59 KB (7,090 words) - 06:49, 30 June 2024
  • pyrimidine metabolism. Zimmerman SB, Kornberg A (May 1961). "Deoxycytidine di- and triphosphate cleavage by an enzyme formed in bacteriophage-infected Eschrichia...
    2 KB (129 words) - 13:44, 26 August 2023
  • Thumbnail for Clofarabine
    cells via hENT1, hENT2, and hCNT2, where upon it is phosphorylated by deoxycytidine kinase to generate clofarabine-5´-monophosphate. The rate-limiting step...
    11 KB (926 words) - 07:57, 25 September 2023
  • Thumbnail for XTP3-transactivated gene A protein
    1 is an enzyme that in humans is encoded by the DCTPP1 gene. Deoxycytidine triphosphate (dCTP) Transactivation GRCh38: Ensembl release 89: ENSG00000179958...
    2 KB (253 words) - 17:54, 4 January 2024
  • Thumbnail for Cytarabine
    by hENT-1. It is then monophosphorylated by deoxycytidine kinase and eventually cytarabine-5´-triphosphate, which is the active metabolite being incorporated...
    19 KB (1,757 words) - 09:15, 29 October 2024
  • Thumbnail for Zalcitabine
    analog of pyrimidine. It is a derivative of the naturally existing deoxycytidine, made by replacing the hydroxyl group in position 3' with a hydrogen...
    11 KB (1,054 words) - 16:44, 29 September 2024
  • Thumbnail for Aciclovir
    required for productive substrate positioning in the active site of human deoxycytidine kinase (dCK): implications for the development of dCK-activated acyclic...
    39 KB (3,730 words) - 07:40, 30 September 2024
  • a synthetic pyrimidine nucleoside analogue, structurally related to deoxycytidine, in which the 3´-hydroxyl group of the ribose sugar moiety is substituted...
    33 KB (3,234 words) - 06:11, 2 November 2024
  • Thumbnail for Cladribine
    Once inside a cell, cladribine undergoes phosphorylation by the enzyme deoxycytidine kinase (DCK) to produce mononucleotide 2-chlorodeoxyadenosine 5’monophosphate...
    43 KB (4,492 words) - 00:15, 27 August 2024
  • deoxycytidylate kinase, CMP kinase, CTP:CMP phosphotransferase, dCMP kinase, deoxycytidine monophosphokinase, UMP-CMP kinase, ATP:UMP-CMP phosphotransferase, and...
    2 KB (203 words) - 15:27, 16 October 2024
  • lymphomas, is converted into cytosine arabinoside triphosphate by deoxycytidine kinase. Mutation of deoxycytidine kinase or loss of expression results in resistance...
    35 KB (3,844 words) - 23:17, 21 July 2024
  • Thumbnail for Nucleoside
    symbol U or Ura uridine symbol U or Urd deoxyuridine symbol dU or dUrd cytosine symbol C or Cyt cytidine symbol C or Cyd deoxycytidine symbol dC or dCyd...
    10 KB (813 words) - 19:42, 12 August 2024
  • carbon of a ribose sugar. Cytosine bonded to deoxyribose is known as deoxycytidine, which is the version used in DNA. cytochemistry The branch of cell...
    315 KB (29,380 words) - 23:23, 22 October 2024
  • Thumbnail for Cytidine
    generated interest as a potential glutamatergic antidepressant drug. Deoxycytidine is cytosine attached to a deoxyribose. William M. Haynes (2016). CRC...
    7 KB (442 words) - 15:25, 24 May 2024
  • Thumbnail for DNA polymerase beta
    MILLIMOLAR) 9icr: DNA POLYMERASE BETA (E.C.2.7.7.7)/DNA COMPLEX + 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, SOAKED IN THE PRESENCE OF DCTP AND MNCL2 9ics: DNA POLYMERASE...
    19 KB (2,214 words) - 09:45, 23 December 2023
  • 246.400 – cytidine triphosphate MeSH D13.695.740.246.425 – deoxycytosine nucleotides MeSH D13.695.740.246.425.300 – deoxycytidine monophosphate MeSH D13...
    42 KB (3,875 words) - 18:21, 20 June 2023
  • Thumbnail for 5-HT2A receptor
    M, Degan P, et al. (March 2010). "Defective repair of 5-hydroxy-2'-deoxycytidine in Cockayne syndrome cells and its complementation by Escherichia coli...
    91 KB (9,992 words) - 04:35, 30 October 2024
  • Thumbnail for Thymidine kinase
    Thd + ATP → TMP + ADP where Thd is (deoxy)thymidine, ATP is adenosine triphosphate, TMP is (deoxy)thymidine monophosphate and ADP is adenosine diphosphate...
    103 KB (11,263 words) - 15:52, 2 November 2024