In organic chemistry, diazirines are a class of organic molecules consisting of a carbon bound to two nitrogen atoms, which are double-bonded to each other...

photoreactive diazirine analogs to leucine and methionine, which are incorporated into proteins. Upon exposure to ultraviolet light, the diazirines are activated...

l-Leucine amino acid. l-photo-leucine is characterized by the presence of a diazirine ring linked to the R radical of the original amino acid. This cyclopropene...

Graham reaction is an oxidation reaction that converts an amidine into a diazirine using a hypohalite reagent. The halide of the hypohalite oxidant, or another...

stable but still isolable isomers of diazomethane include the cyclic 3H-diazirine and isocyanoamine (isodiazomethane). In addition, the parent nitrilimine...

vitro. Photo-reactive amino acid analogs in common use are photoreactive diazirine analogs to leucine and methionine, and para-benzoylphenylalanine. Upon...

such as ketene (ethenone) (CH 2=CO), diazomethane (linear CH 2=N 2), diazirine (cyclic [-CH 2-N=N-]) and diiodomethane (I-CH 2-I). The decomposition...

mammalian GABAA receptors has been identified by photolabeling using a diazirine derivative. Additionally, it was shown that the hyaluronan polymer present...

CH2N2 may refer to: Cyanamide, an organic compound Diazirine, class of organic molecules with a cyclopropene-like ring, 3H-diazirene Diazomethane, chemical...

functional groups are replaced with a photoreactive group, such as an azide, a diazirine or a benzophenone. Photoaffinity labeling Photoaffinity labeling, Gold...

produced from an extrusion reaction with a large free energy change. Diazirines and epoxides photolyze with a tremendous release in ring strain to carbenes...

leverages the photonic energy of iridium-based photocatalysts to activate diazirine probes that can tag proximal proteins within a tight radius of about four...

heteroatoms Heteroatoms Saturated Unsaturated 2× Nitrogen Diaziridine Diazirine Nitrogen + oxygen Oxaziridine Oxazirine 2× Oxygen Dioxirane (highly unstable)...

TDBzcholine is a diazirine analog of acetylcholine that can be used to label the nicotinic acetylcholine receptor. TDBzcholine is able to bind to the...

group of isomeric compounds with only few similar properties are the diazirines, where the carbon and two nitrogens are linked as a ring. Four resonance...

photoreactive diazirine analogs to leucine and methionine, which are incorporated into proteins. Upon exposure to ultraviolet light, the diazirines are activated...

facilitate a better understanding of biological mechanisms. RNP-MaP uses NHS-diazirine (SDA), a hetero-bifunctional crosslinker, to freeze RNA-bound proteins...

previous synthesis had worked, photo-methionine is photo-reactive due to the diazirine ring. Once this ring has become exposed to UV light, nitrogen leaves as...

mammalian GABAA receptors has been identified by photolabeling using a diazirine derivative. Strong activation of tonic GABAA receptor conductance by clinical...

diaziridines are often directly oxidized (I2/NEt3) to the more stable diazirines. They can undergo ring expansion reaction with electrophilic reagents...

2001). "Interactions between 3-(trifluoromethyl)-3-(m-[125I]iodophenyl)diazirine and tetracaine, phencyclidine, or histrionicotoxin in the Torpedo species...

O-GlcNAcylated proteins. The N-acetyl group may be elongated to incorporate a diazirine moiety. Treatment of cells with peracetylated, phosphate-protected...

Dailey et al. reported that the photolysis of 3-bromo-3-(trifluoromethyl)diazirines in an argon matrix could afford bromo(trifluoromethyl)carbene....

fragmentation. A closely related fragmentation has been reported, employing diazirine derivatives of cyclic α,β-epoxyketones. Grob fragmentation Wharton reaction...

cyclohexanone) diaziridines, which can easily be oxidized to the more stable diazirines. The reaction also provides substituted aziridines from simple aldehydes...

Kaiser, Markus; Bayer, Peter (2020). "Targeting of parvulin interactors by diazirine mediated cross-linking discloses a cellular role of human Par14/17 in...

synthesis, iterative cross-coupling, and accessing reactive, unstable diazirines.[citation needed] It is designed to perform these reactions in a single...

Kaiser, Markus; Bayer, Peter (2020). "Targeting of parvulin interactors by diazirine mediated cross-linking discloses a cellular role of human Par14/17 in...

orally, among the highest noted. Church RF, Kende AS, Weiss MJ (1965). "Diazirines. I. Some Observations on the Scope of the Ammonia-Hydroxylamine-O-sulfonic...