molecules of dihydrolipoyl transacetylase (E2). Up to 16 homodimers of pyruvate dehydrogenase (E1) and 8 homodimers of dihydrolipoyl dehydrogenase (E3) bind...
29 KB (3,340 words) - 20:01, 15 August 2024
Dihydrolipoyl transacetylase (or dihydrolipoamide acetyltransferase) is an enzyme component of the multienzyme pyruvate dehydrogenase complex. The pyruvate...
21 KB (2,487 words) - 00:19, 8 June 2024
Dihydrolipoamide dehydrogenase (DLD), also known as dihydrolipoyl dehydrogenase, mitochondrial, is an enzyme that in humans is encoded by the DLD gene...
21 KB (2,346 words) - 00:15, 8 June 2024
and E3, which regenerates lipoamide from dihydrolipoamide, is dihydrolipoyl dehydrogenase. Starting at the left-hand side, the thiazolium form of the TPP...
12 KB (1,563 words) - 10:53, 6 August 2024
copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT) (E2; EC 2.3.1.12); and dihydrolipoyl dehydrogenase (DLD) (E3; EC 1.8.1.4). The E1 enzyme...
22 KB (2,885 words) - 20:23, 2 January 2024
More rarely, mutations occur in the E2 (dihydrolipoyl transacetylase) or the E3 (dihydrolipoyl dehydrogenase) subunits of the PDC enzymatic complex, DLAT...
20 KB (2,217 words) - 02:43, 11 October 2023
The oxoglutarate dehydrogenase complex (OGDC) or α-ketoglutarate dehydrogenase complex is an enzyme complex, most commonly known for its role in the citric...
17 KB (1,893 words) - 16:48, 27 June 2024
Pyruvate dehydrogenase has three chemical compartments; E1 (pyruvate decarboxylase), E2 (dihydrolipoyl transacetylase) and E3 (dihydrolipoyl dehydrogenase)....
1 KB (157 words) - 04:38, 6 January 2024
oxidized by dihydrolipoyl dehydrogenase in order to produce lipoamide. Lipoamide is subsequently used as a cofactor for α-ketoglutarate dehydrogenase, the pyruvate...
2 KB (88 words) - 14:19, 18 August 2022
dehydrogenase EC 1.8.1.1: deleted EC 1.8.1.2: sulfite reductase (NADPH) EC 1.8.1.3: hypotaurine dehydrogenase EC 1.8.1.4: dihydrolipoyl dehydrogenase...
189 KB (24,607 words) - 12:36, 11 June 2024
(1985). "Subunit structure of the dihydrolipoyl transacylase component of branched-chain alpha-keto acid dehydrogenase complex from bovine liver. Characterization...
16 KB (1,781 words) - 18:08, 24 April 2024
Dihydrolipoyllysine-residue succinyltransferase (redirect from Succinyl-CoA:enzyme-N6-(dihydrolipoyl)lysine S-succinyltransferase)
and preliminary structural analysis of dihydrolipoyl transsuccinylase, the core of the 2-oxoglutarate dehydrogenase complex". Proc. Natl. Acad. Sci. U.S...
3 KB (326 words) - 13:50, 26 August 2023
evaluation of the lipoyl domains of the dihydrolipoyl acetyltransferase component of the human pyruvate dehydrogenase complex". Arch. Biochem. Biophys. 316...
12 KB (1,616 words) - 09:57, 3 June 2024
Dihydrolipoyllysine-residue (2-methylpropanoyl)transferase (redirect from 2-methylpropanoyl-CoA:enzyme-N6-(dihydrolipoyl)lysine S-(2-methylpropanoyl)transferase)
structural properties of the dihydrolipoyl transacylase component of bovine branched-chain alpha-keto acid dehydrogenase". J. Biol. Chem. 259 (14): 9277–84...
3 KB (325 words) - 13:50, 26 August 2023
lowered efficiency of the glycine cleavage system. dihydrolipoamide dehydrogenase lipoic acid glycine encephalopathy Kikuchi G (June 1973). "The glycine...
12 KB (1,267 words) - 10:23, 19 June 2024
an estrogen steroid hormone Dihydrolipoyl transacetylase, the second element of the multienzyme pyruvate dehydrogenase complex Acireductone dioxygenase...
4 KB (571 words) - 00:32, 29 July 2024
"The complete cDNA sequence for dihydrolipoyl transacylase (E2) of human branched-chain alpha-keto acid dehydrogenase complex". Biochim Biophys Acta....
9 KB (1,085 words) - 00:21, 8 June 2024
PDK2 (redirect from Pyruvate dehydrogenase kinase 2)
2003). "Facilitated interaction between the pyruvate dehydrogenase kinase isoform 2 and the dihydrolipoyl acetyltransferase". The Journal of Biological Chemistry...
16 KB (1,929 words) - 07:41, 4 January 2024
enzymes: pyruvate dehydrogenase, α-ketoglutarate dehydrogenase, the glycine cleavage system, branched-chain alpha-keto acid dehydrogenase, and the α-oxo(keto)adipate...
48 KB (4,958 words) - 01:02, 6 August 2024
protein, nucleoside triphosphatase YtkD, protease modulator HflC, dihydrolipoyl dehydrogenase, DUF3603 family protein, M20/M25/M40 family metallohydrolase...
6 KB (607 words) - 17:34, 17 April 2024
characterization, and mapping of gene encoding dihydrolipoyl succinyltransferase (E2k) of human alpha-ketoglutarate dehydrogenase complex". Somat Cell Mol Genet. 20...
8 KB (968 words) - 18:03, 20 November 2023
evaluation of the lipoyl domains of the dihydrolipoyl acetyltransferase component of the human pyruvate dehydrogenase complex". Arch. Biochem. Biophys. 316...
12 KB (1,599 words) - 17:36, 4 January 2024
2003). "Facilitated interaction between the pyruvate dehydrogenase kinase isoform 2 and the dihydrolipoyl acetyltransferase". The Journal of Biological Chemistry...
19 KB (2,614 words) - 00:20, 8 June 2024
decarboxylase (E1), a homo-24-meric dihydrolipoyl transacylase (E2; MIM 248610), and a homodimeric dihydrolipoamide dehydrogenase (E3; MIM 238331). The reaction...
16 KB (2,092 words) - 00:13, 8 June 2024
tetrahydrofolate, while the L-protein, a lipoamide dehydrogenase, catalyzes the oxidation of the dihydrolipoyl residue of H-protein and reduction of NAD. Human...
12 KB (1,457 words) - 09:36, 8 January 2024