A diketopiperazine (DKP), also known as a dioxopiperazine or piperazinedione, is a class of organic compounds related to piperazine but containing two...
4 KB (413 words) - 03:16, 28 November 2023
2,5-Diketopiperazine is an organic compound with the formula (NHCH2C(O))2. The compound features a six-membered ring containing two amide groups at opposite...
22 KB (2,289 words) - 13:18, 29 June 2024
Retrieved 5 August 2024. Of course if on Earth there had only been diketopiperazines and not amino acids; or if sugars did not have the size they have;...
98 KB (10,138 words) - 17:57, 6 August 2024
2CONHCH 2COO− + H2O Pyrolysis of glycine or glycylglycine gives 2,5-diketopiperazine, the cyclic diamide. It forms esters with alcohols. They are often...
38 KB (3,403 words) - 03:29, 5 August 2024
Tadalafil (category Diketopiperazines)
body of inhibiting PDE11 are not known. Tadalafil is an annulated 2,5-diketopiperazine. It is also a 1,2,3,4-tetrahydro-β-carboline. Tadalafil can be synthesized...
36 KB (3,239 words) - 12:12, 6 August 2024
Penicillium which occurs in kangaroo rats and produces penicillin and the diketopiperazine dipodazine. List of Penicillium species MycoBank UniProt Henk, D. A...
3 KB (198 words) - 22:28, 16 January 2024
coffee. The bitter flavor of diketopiperazines is perceptible at around 20 mg/liter of water. The content of diketopiperazines in espresso is about 20 to...
33 KB (4,085 words) - 04:31, 18 June 2024
tending to polymerize when stored at room temperature or convert to diketopiperazine. The hydrochloride is shelf-stable. "Glycine methyl ester hydrochloride"...
3 KB (194 words) - 10:03, 21 September 2023
Partisi, Revolutionary Communard Party, Turkey Diketopiperazine, a class of organic compounds 2,5-Diketopiperazine, a specific form Duffin–Kemmer–Petiau algebra...
917 bytes (136 words) - 11:23, 19 February 2024
Verruculogen (category Diketopiperazines)
of aspergillus that belongs to a class of naturally occurring 2,5-diketopiperazines. It is an annulated analogue of cyclo(L-Trp-L-Pro) which belongs to...
3 KB (198 words) - 14:34, 25 September 2023
synthesized by Emil Fischer and Ernest Fourneau in 1901 by boiling 2,5-diketopiperazine (glycine anhydride) with hydrochloric acid. Shaking with alkali and...
6 KB (393 words) - 17:18, 18 June 2024
Dipeptides activate G-cells found in the stomach to secrete gastrin. Diketopiperazines are a special class of dipeptides, which are cyclic. They form as...
7 KB (749 words) - 14:33, 28 May 2024
stored at a relatively high temperature can lead to the formation of diketopiperazine, a cyclo (Pro-Leu) that makes it bitter as it ages Sake has high microbiological...
102 KB (11,861 words) - 20:42, 4 June 2024
Fumitremorgin (category Diketopiperazines)
and Penicillium, that belong to a class of naturally occurring 2,5-diketopiperazines. Biosynthesis pathway of fumitremorgin pathway involves several different...
3 KB (335 words) - 00:22, 22 February 2024
acid Dihydrouracil, an intermediate in the catabolism of uracil 2,5-Diketopiperazine Ethyl diazoacetate, a reagent used in organic chemistry Muscimol, the...
490 bytes (78 words) - 20:55, 9 August 2019
to the alpha amine of another). The smallest such species are 2,5-diketopiperazines, being derived from the cyclisation of a dipeptide. Cyclic isopeptides...
6 KB (742 words) - 00:40, 1 November 2023
structures of proteins were proposed by various researchers, such as the diketopiperazine model of Emil Abderhalden and the pyrrol/piperidine model of Troensegaard...
21 KB (2,595 words) - 15:26, 27 May 2024
Brevianamide F (category Diketopiperazines)
cyclo-(L-Trp-L-Pro), belongs to a class of naturally occurring 2,5-diketopiperazines. It is the simplest member and the biosynthetic precursor of a large...
6 KB (560 words) - 16:41, 4 January 2024
Drimentine G (category Diketopiperazines)
(DMT G) belongs to the family of drimentines, which are terpenylated diketopiperazines. As the name suggests, DMT G contains two different parts, one comes...
7 KB (674 words) - 15:35, 11 June 2024
employed as the enolate-forming component of the condensation. 2,5-Diketopiperazine can be used as a methylene component as well; its condensation products...
5 KB (578 words) - 12:26, 26 March 2023
Retosiban (category Diketopiperazines)
22 mg/ml), with a logd of 2.2. Retosiban consists of a central 2,5 diketopiperazine ring with an R-indanyl group at the 3 position and an R (S-secButyl)...
10 KB (1,099 words) - 16:40, 19 December 2023
Gliotoxin (category Diketopiperazines)
sulfur-containing mycotoxin that belongs to a class of naturally occurring 2,5-diketopiperazines produced by several species of fungi, especially those of marine origin...
31 KB (3,171 words) - 18:28, 7 June 2024
insulin. It includes powder-dissolved recombinant human insulin (fumaryl diketopiperazine). Technosphere insulin is quickly absorbed by the lung surface after...
110 KB (11,398 words) - 13:41, 20 July 2024
of compound Discovered/described by Biactivities Structure barettin diketopiperazine (monobrominated) Lidgren, Bohlin and Bergman (1986) antifouling selective...
33 KB (3,032 words) - 07:30, 22 June 2024
Piscarinine (category Diketopiperazines)
piscarium Westling that belong to a class of naturally occurring 2,5-diketopiperazines. The cytotoxic dehydroproline tryptophan derivatives piscarinines...
2 KB (159 words) - 00:28, 7 April 2022
Piperacillin (category Diketopiperazines)
Piperacillin is a broad-spectrum β-lactam antibiotic of the ureidopenicillin class. The chemical structure of piperacillin and other ureidopenicillins...
44 KB (4,767 words) - 05:13, 3 June 2024
related compounds. Enzymatic epoxidation of phenylalanine-derived diketopiperazine forms the arene oxide, which undergoes a 6π disrotatory ring opening...
10 KB (1,268 words) - 20:37, 22 July 2024
Bicyclomycin (category Diketopiperazines)
aizumenses in 1972. It belongs to a class of naturally occurring 2,5-diketopiperazines, that are among the most numerous of all the naturally occurring peptide...
9 KB (839 words) - 21:35, 21 November 2023
did not allow for the incorporation of functionality on the interior diketopiperazine (DKP) nitrogens. Much work has been done to allow for the functionalization...
9 KB (869 words) - 21:56, 12 February 2024
Roquefortine C (category Diketopiperazines)
is a mycotoxin that belongs to a class of naturally occurring 2,5-diketopiperazines produced by various fungi, particularly species from the genus Penicillium...
7 KB (566 words) - 20:24, 29 January 2023