• Thumbnail for Discoidin domain
    Discoidin domain (also known as F5/8 type C domain, or C2-like domain) is major protein domain of many blood coagulation factors. Blood coagulation factors...
    6 KB (723 words) - 07:51, 27 August 2021
  • Thumbnail for Discoidin domain-containing receptor 2
    Discoidin domain-containing receptor 2, also known as CD167b (cluster of differentiation 167b), is a protein that in humans is encoded by the DDR2 gene...
    11 KB (1,397 words) - 20:28, 3 March 2023
  • Thumbnail for Receptor tyrosine kinase
    Mahasenan KV, Mobashery S, Huang P, Agarwal G, Fridman R (March 2013). "Discoidin domain receptors: unique receptor tyrosine kinases in collagen-mediated signaling"...
    28 KB (3,078 words) - 07:46, 3 June 2024
  • Thumbnail for DDR1
    Discoidin domain receptor family, member 1, also known as DDR1 or CD167a (cluster of differentiation 167a), is a human gene. Receptor tyrosine kinases...
    10 KB (1,207 words) - 19:16, 27 March 2024
  • integrin α10β2, which is situated on monocytes and binds type I collagen. Discoidin domain receptors form a subgroup of receptor tyrosine kinases. Receptor activation...
    8 KB (1,090 words) - 21:55, 30 September 2023
  • Thumbnail for Spondylo-meta-epiphyseal dysplasia
    skeletal disorders. SMED is thought to be caused by a mutation in the Discoidin Domain Receptor 2 (DDR2) gene. Spondyloepimetaphyseal dysplasia-short limb-abnormal...
    3 KB (190 words) - 16:12, 21 October 2024
  • F58 may refer to: F5/8 type C domain (Discoidin domain) is a major protein domain of many blood coagulation factors HMS Hermione (F58), Leander-class...
    467 bytes (99 words) - 21:22, 24 August 2018
  • Thumbnail for WWC1
    Kaplan W, Daly RJ, Ormandy CJ (March 2008). "KIBRA interacts with discoidin domain receptor 1 to modulate collagen-induced signalling". Biochimica et...
    10 KB (1,113 words) - 08:17, 23 October 2024
  • Thumbnail for Factor VIII
    copper-binding protein ceruloplasmin. The C domains belong to the phospholipid-binding discoidin domain family, and the C2 domain mediate membrane binding. Activation...
    17 KB (2,001 words) - 15:23, 28 August 2024
  • Thumbnail for Factor V
    with the plasma. The C domains belong to the phospholipid-binding discoidin domain family (unrelated to C2 domain), and the C2 domain mediates membrane binding...
    14 KB (1,814 words) - 07:38, 3 June 2024
  • Discoidal cleavage, a type of partial cleavage in embryos Discoidin domain, a protein domain of many blood coagulation factors Blaberus discoidalis, the...
    947 bytes (146 words) - 19:10, 5 November 2022
  • Thumbnail for Peripheral membrane protein
    domain and certain PDZ domains. They bind PtdIns(4,5)P2. Discoidin domains of blood coagulation factors ENTH, VHS and ANTH domains Structural domains...
    55 KB (4,414 words) - 20:08, 7 October 2024
  • Thumbnail for Tumor microenvironment
    and bind to the ECM through transmembrane receptors like integrins, discoidin domain receptor 2 (DDRs), and syndecans. The transmission of signals from...
    65 KB (6,977 words) - 12:40, 13 October 2024
  • Thumbnail for Neuropilin
    four domains: N-terminal CUB domain (for complement C1r/C1s, Uegf, Bmp1) Coagulation factor 5/8 type, C-terminal (discoidin domain) MAM domain (for meprin...
    11 KB (1,055 words) - 03:34, 23 June 2024
  • Desmin Marker for maturation of microvessels (to mark for angiogenesis) Discoidin domain-containing receptor 2 (DDR2) Platelet derived growth factor receptor-α...
    31 KB (3,599 words) - 19:59, 30 June 2024
  • ligand for CD6 and involved in neurite extension CD167a Epithelial discoidin domain-containing receptor 1, encoded by DDR1 gene; tyrosine kinase that functions...
    96 KB (467 words) - 19:33, 6 August 2024
  • Thumbnail for Collagen, type X, alpha 1
    chondrodysplasia)". Kwan et al. 2005 Leitinger B, Kwan AP (August 2006). "The discoidin domain receptor DDR2 is a receptor for type X collagen". Matrix Biol. 25 (6):...
    10 KB (1,321 words) - 06:15, 15 January 2024
  • Thumbnail for LCCL domain
    complement B-type domains, C-type lectin domains, von Willebrand type A domains, CUB domains, discoidin lectin domains or CAP domains. It has been proposed...
    4 KB (415 words) - 04:30, 1 January 2021
  • K.; Ford, C. E. (2007). "Expression and mutation analysis of the discoidin domain receptors 1 and 2 in non-small cell lung carcinoma". British Journal...
    11 KB (968 words) - 11:33, 25 July 2024
  • Thumbnail for Retinoschisin
    becomes functional), and a highly conserved sequence motif called the discoidin domain which consists of 157 amino acids, important for the protein's function...
    14 KB (1,783 words) - 03:22, 27 April 2024
  • Thumbnail for Mir-199 microRNA precursor
    Gerken G, Beckebaum S (August 2010). "Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion". Molecular Cancer...
    11 KB (1,280 words) - 09:14, 1 December 2023
  • Thumbnail for FRS2
    Bradshaw RA (May 2000). "Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric...
    16 KB (1,851 words) - 19:13, 27 March 2024
  • Thumbnail for EDIL3
    EGF like repeats and discoidin domains 3 is a protein that in humans is encoded by the EDIL3 gene. The protein encoded by this gene is an integrin ligand...
    4 KB (592 words) - 09:02, 6 September 2023
  • Thumbnail for SOS1
    Dimarco E, et al. (May 2000). "Discoidin domain receptor 1 (DDR1) signaling in PC12 cells: activation of juxtamembrane domains in PDGFR/DDR/TrkA chimeric...
    32 KB (3,595 words) - 10:04, 27 March 2024
  • Thumbnail for Kelch protein
    contain other protein domains, including Discoidin, F-box, and Broad-complex, Tramtrack, Bric-a-Brac/Poxvirus Zinc finger (BTB/POZ) domains. Kelch proteins...
    5 KB (531 words) - 17:36, 18 February 2024
  • Thumbnail for DCBLD2
    Discoidin, CUB and LCCL domain-containing protein 2 is a protein that in humans is encoded by the DCBLD2 gene. GRCh38: Ensembl release 89: ENSG00000057019...
    3 KB (423 words) - 11:02, 17 January 2024
  • Thumbnail for CNTNAP2
    G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and...
    11 KB (1,355 words) - 23:40, 23 October 2024
  • Thumbnail for Muskelin
    (2004). "Molecular analysis of muskelin identifies a conserved discoidin-like domain that contributes to protein self-association". Biochem. J. 381 (Pt...
    4 KB (538 words) - 23:54, 3 March 2023
  • Thumbnail for CNTNAP4
    repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, and thrombospondin N-terminal-like...
    4 KB (485 words) - 13:52, 28 October 2022
  • Thumbnail for Subcommissural organ
    a coagulation factor 5/8 type C (FA5-8C) or discoidin motif and a C-terminal cystin knot (CTCK) domain provides a wider insight into the putative function...
    29 KB (3,542 words) - 20:53, 17 August 2024