• Thumbnail for Dose–response relationship
    The doseresponse relationship, or exposure–response relationship, describes the magnitude of the response of an organism, as a function of exposure (or...
    17 KB (1,788 words) - 21:35, 5 September 2024
  • DoseResponse is a quarterly peer-reviewed scientific journal covering research on the dose-response relationship, especially hormesis. It was established...
    3 KB (182 words) - 00:15, 26 April 2023
  • sigmoidal doseresponse curves. Thus, a favorable outcome in doseresponse for tumor tissue is greater than that of normal tissue for the same dose, meaning...
    25 KB (3,220 words) - 09:30, 20 November 2024
  • Thumbnail for Hormesis
    is a two-phased dose-response relationship to an environmental agent whereby low-dose amounts have a beneficial effect and high-dose amounts are either...
    32 KB (3,494 words) - 16:25, 24 November 2024
  • Thumbnail for Linear no-threshold model
    The linear no-threshold model (LNT) is a dose-response model used in radiation protection to estimate stochastic health effects such as radiation-induced...
    39 KB (4,584 words) - 02:24, 25 July 2024
  • Thumbnail for Radiation hormesis
    theoretical studies indicate that the adaptive response is responsible for the shape of dose-response curve and can transform the linear relationship...
    56 KB (6,794 words) - 17:08, 6 November 2024
  • Threshold dose is the minimum dose of drug that triggers minimal detectable biological effect in an animal. At extremely low doses, biological responses are...
    23 KB (2,910 words) - 06:26, 27 September 2023
  • Thumbnail for Hill equation (biochemistry)
    ligand binding sites. The Hill equation (for response) is important in the construction of dose-response curves. The Hill equation is commonly expressed...
    30 KB (3,330 words) - 13:07, 4 October 2024
  • Thumbnail for Toxicology
    and treating exposures to toxins and toxicants. The relationship between dose and its effects on the exposed organism is of high significance in toxicology...
    37 KB (4,044 words) - 01:46, 22 October 2024
  • criteria intended to protect the health of consumers. The concept of a dose-response relationship dates back to as 1493 but its modern usage reaches to the...
    9 KB (1,288 words) - 00:39, 3 June 2024
  • Thumbnail for EC50
    dose response curve shows the graded effect of the drug (y axis) over the dose of the drug (x axis) in one or an average of subjects. A quantal dose response...
    9 KB (1,023 words) - 21:43, 27 August 2024
  • Thumbnail for Drug titration
    Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects. When a drug has a narrow therapeutic...
    4 KB (385 words) - 22:40, 20 November 2024
  • Thumbnail for Radiation exposure
    linear dose response for all solid tumors. This means the relationship between dose and human body response is a straight line. The risk of low dose radiation...
    33 KB (3,707 words) - 12:06, 30 August 2024
  • effective dose (ED) or effective concentration (EC) is the dose or concentration of a drug that produces a biological response. The term "effective dose" is...
    6 KB (684 words) - 16:56, 21 January 2024
  • and many other fields. Pharmacological dose response relationships are an application of stimulus-response models. Another field this model can be applied...
    11 KB (1,309 words) - 13:00, 20 November 2024
  • Thumbnail for Toxicity
    cell). Because individuals typically have different levels of response to the same dose of a toxic substance, a population-level measure of toxicity is...
    30 KB (3,274 words) - 10:06, 15 September 2024
  • The first-dose phenomenon is a sudden and severe fall in blood pressure that can occur when changing from a lying to a standing position the first time...
    4 KB (428 words) - 06:47, 8 November 2023
  • Thumbnail for CT scan
    and health: and the benefits of low-dose radiation hormesis". Dose-Response. 7 (1): 52–89. doi:10.2203/dose-response.08-024.Cuttler. PMC 2664640. PMID 19343116...
    155 KB (16,193 words) - 04:34, 25 November 2024
  • Look up Dose, dose, dosage, or dosis in Wiktionary, the free dictionary. Dose or Dosage may refer to: Dose (Gov't Mule album), 1998 Dose (Latin Playboys...
    2 KB (273 words) - 18:54, 30 September 2024
  • Thumbnail for Potency (pharmacology)
    doi:10.1124/pr.55.4.4. PMID 14657418. S2CID 1729572. "Introducing dose response curves". Graphpad Software. Archived from the original on 2012-07-30...
    4 KB (262 words) - 04:46, 8 August 2024
  • Thumbnail for Agonist
    biological response. When a drug is used therapeutically, it is important to understand the margin of safety that exists between the dose needed for the...
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  • Thumbnail for Epirubicin
    however, response rates and durations are generally lower than those seen after initial treatment with these regimens (FEC and FAC). A reduced dose intensity...
    24 KB (2,750 words) - 06:08, 3 January 2024
  • Thumbnail for Isotonic regression
    Flournoy and shown to substantially reduce estimation error for both dose-response and dose-finding applications. Both CIR and the standard isotonic regression...
    10 KB (1,449 words) - 12:08, 24 October 2024
  • Thumbnail for Eggs as food
    M (2016). "Egg consumption and risk of incident type 2 diabetes: a doseresponse meta-analysis of prospective cohort studies". British Journal of Nutrition...
    94 KB (10,445 words) - 22:10, 19 November 2024
  • Thumbnail for Endocrine disruptor
    poison' rule of toxicology. Nontraditional dose-response curves are referred to as non-monotonic dose response curves." It has been claimed that tamoxifen...
    150 KB (17,094 words) - 05:07, 17 November 2024
  • minimizing side effects due to the vaccine. Fractional dose vaccination exploits the nonlinear dose-response characteristics of a vaccine: If two persons can...
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  • Thumbnail for Pharmacology
    produce a biological response. The ability of a ligand to produce a biological response is termed efficacy, in a dose-response profile it is indicated...
    48 KB (4,744 words) - 01:42, 17 November 2024
  • Thumbnail for Receptor antagonist
    biological response of an agonist. Elucidating an IC50 value is useful for comparing the potency of drugs with similar efficacies, however the dose-response curves...
    33 KB (3,845 words) - 01:47, 19 August 2024
  • Thumbnail for Fukushima nuclear accident
    "Radiation Hormesis: The Good, the Bad, and the Ugly". Dose-Response. 4 (3): 189–190. doi:10.2203/dose-response.06-102.Luckey. PMC 2477686. PMID 18648595. Hamada...
    187 KB (17,450 words) - 01:05, 17 November 2024
  • Thumbnail for Caffeine dependence
    et al.(1991) were at one dose and small. This is similar to our current data; the lower doses of caffeine on our dose-response curve are weakly, but non-significantly...
    26 KB (2,812 words) - 19:35, 14 October 2024