The dose–response relationship, or exposure–response relationship, describes the magnitude of the response of an organism, as a function of exposure (or...
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Dose–Response is a quarterly peer-reviewed scientific journal covering research on the dose-response relationship, especially hormesis. It was established...
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Therapeutic index (redirect from Therapeutic dose)
sigmoidal dose–response curves. Thus, a favorable outcome in dose–response for tumor tissue is greater than that of normal tissue for the same dose, meaning...
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is a two-phased dose-response relationship to an environmental agent whereby low-dose amounts have a beneficial effect and high-dose amounts are either...
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Linear no-threshold model (redirect from Maximum permissible dose)
The linear no-threshold model (LNT) is a dose-response model used in radiation protection to estimate stochastic health effects such as radiation-induced...
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theoretical studies indicate that the adaptive response is responsible for the shape of dose-response curve and can transform the linear relationship...
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Threshold dose is the minimum dose of drug that triggers minimal detectable biological effect in an animal. At extremely low doses, biological responses are...
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Hill equation (biochemistry) (section Tissue response)
ligand binding sites. The Hill equation (for response) is important in the construction of dose-response curves. The Hill equation is commonly expressed...
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Toxicology (section Dose response complexities)
and treating exposures to toxins and toxicants. The relationship between dose and its effects on the exposed organism is of high significance in toxicology...
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criteria intended to protect the health of consumers. The concept of a dose-response relationship dates back to as 1493 but its modern usage reaches to the...
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dose response curve shows the graded effect of the drug (y axis) over the dose of the drug (x axis) in one or an average of subjects. A quantal dose response...
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Drug titration (redirect from Dose titration)
Drug titration is the process of adjusting the dose of a medication for the maximum benefit without adverse effects. When a drug has a narrow therapeutic...
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linear dose response for all solid tumors. This means the relationship between dose and human body response is a straight line. The risk of low dose radiation...
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effective dose (ED) or effective concentration (EC) is the dose or concentration of a drug that produces a biological response. The term "effective dose" is...
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and many other fields. Pharmacological dose response relationships are an application of stimulus-response models. Another field this model can be applied...
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cell). Because individuals typically have different levels of response to the same dose of a toxic substance, a population-level measure of toxicity is...
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The first-dose phenomenon is a sudden and severe fall in blood pressure that can occur when changing from a lying to a standing position the first time...
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CT scan (section Dose versus image quality)
and health: and the benefits of low-dose radiation hormesis". Dose-Response. 7 (1): 52–89. doi:10.2203/dose-response.08-024.Cuttler. PMC 2664640. PMID 19343116...
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Look up Dose, dose, dosage, or dosis in Wiktionary, the free dictionary. Dose or Dosage may refer to: Dose (Gov't Mule album), 1998 Dose (Latin Playboys...
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doi:10.1124/pr.55.4.4. PMID 14657418. S2CID 1729572. "Introducing dose response curves". Graphpad Software. Archived from the original on 2012-07-30...
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biological response. When a drug is used therapeutically, it is important to understand the margin of safety that exists between the dose needed for the...
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Epirubicin (section Dose response)
however, response rates and durations are generally lower than those seen after initial treatment with these regimens (FEC and FAC). A reduced dose intensity...
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Flournoy and shown to substantially reduce estimation error for both dose-response and dose-finding applications. Both CIR and the standard isotonic regression...
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M (2016). "Egg consumption and risk of incident type 2 diabetes: a dose–response meta-analysis of prospective cohort studies". British Journal of Nutrition...
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poison' rule of toxicology. Nontraditional dose-response curves are referred to as non-monotonic dose response curves." It has been claimed that tamoxifen...
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minimizing side effects due to the vaccine. Fractional dose vaccination exploits the nonlinear dose-response characteristics of a vaccine: If two persons can...
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produce a biological response. The ability of a ligand to produce a biological response is termed efficacy, in a dose-response profile it is indicated...
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biological response of an agonist. Elucidating an IC50 value is useful for comparing the potency of drugs with similar efficacies, however the dose-response curves...
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Fukushima nuclear accident (section Immediate response)
"Radiation Hormesis: The Good, the Bad, and the Ugly". Dose-Response. 4 (3): 189–190. doi:10.2203/dose-response.06-102.Luckey. PMC 2477686. PMID 18648595. Hamada...
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Caffeine dependence (section Dose tapering)
et al.(1991) were at one dose and small. This is similar to our current data; the lower doses of caffeine on our dose-response curve are weakly, but non-significantly...
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