domain-containing protein 1 (EPAS1, also known as hypoxia-inducible factor-2alpha (HIF-2α)) is a protein that is encoded by the EPAS1 gene in mammals. It is...
22 KB (2,683 words) - 21:13, 23 October 2024
Per-Arnt-Sim (PAS) domain protein 1 (EPAS1). It was found that one single-nucleotide polymorphism (SNP) at EPAS1 shows a 78% frequency difference between...
52 KB (5,651 words) - 22:13, 16 July 2024
deeply-diverged from modern Holarctic wolves and dogs has contributed the EPAS1 allele found in both Himalayan wolves and dogs, and this allows them to...
20 KB (2,360 words) - 11:12, 31 October 2024
continents. Tibetan humans and Tibetan domestic dogs share a genetic mutation in EPAS1, but it has not been seen in Andean humans. Tardigrades live over the entire...
52 KB (5,509 words) - 00:00, 18 October 2024
that make Tibetans' bodies well-suited for high-altitudes, including the EPAS1 gene, also referred to as the "super-athlete gene", which regulates the...
49 KB (4,959 words) - 23:28, 9 October 2024
brown eyes. The Denisovan genome also contains a variant region around the EPAS1 gene that in Tibetans assists with adaptation to low oxygen levels at high...
73 KB (7,460 words) - 22:13, 12 November 2024
factors that make Tibetan bodies well-suited for high altitudes, including EPAS1, referred to as the "super-athlete gene," that regulates the body's production...
47 KB (5,201 words) - 01:00, 16 November 2024
Tibetans evolving over 3,000 years to have high proportions of an allele of EPAS1 that is adaptive to high altitudes. Other evolution is related to endemic...
263 KB (26,337 words) - 01:57, 16 November 2024
alleles' high mutation rate. Tibetan people received an advantageous EGLN1 and EPAS1 gene variant, associated with hemoglobin concentration and response to hypoxia...
92 KB (11,168 words) - 22:35, 6 November 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
42 KB (4,879 words) - 13:27, 9 October 2024
contributed 39% to the Himalayan wolf's nuclear genome, and contributed the EPAS1 allele which can be found in both Himalayan wolves and dogs which allows...
56 KB (5,583 words) - 12:59, 5 October 2024
and wolves living in the Himalayas and on the Tibetan plateau carry the EPAS1 allele that is associated with high-altitude oxygen adaptation, which has...
172 KB (20,432 words) - 16:54, 10 November 2024
ENSG00000163508 T-box Known motif – High-throughput in vitro [202] WTCACACCTH EPAS1 ENSG00000116016 bHLH Known motif – In vivo/Misc source [203] VDACGTGHH ERF...
374 KB (81 words) - 02:10, 23 September 2023
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
20 KB (2,045 words) - 23:47, 25 October 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
18 KB (1,897 words) - 23:57, 4 October 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
41 KB (4,385 words) - 21:28, 21 August 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
17 KB (2,005 words) - 23:01, 20 August 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
39 KB (4,859 words) - 19:32, 22 August 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
24 KB (2,820 words) - 05:34, 10 July 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
57 KB (6,672 words) - 01:42, 9 October 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
5 KB (593 words) - 20:14, 3 June 2022
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
29 KB (3,402 words) - 07:08, 20 May 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
6 KB (702 words) - 00:43, 29 November 2023
as the Sherpas from Nepal is believed to have inherited an allele called EPAS1, which allows them to breathe easily at high altitudes, from the Denisovans...
101 KB (11,819 words) - 01:21, 5 November 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
28 KB (3,340 words) - 22:59, 25 September 2024
(December 2019). "Vascular Changes in the Retina and Choroid of Patients With EPAS1 Gain-of-Function Mutation Syndrome". JAMA Ophthalmology. 138 (2): 148–155...
151 KB (16,268 words) - 03:01, 14 October 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
124 KB (13,220 words) - 11:01, 30 August 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
74 KB (8,192 words) - 09:41, 10 November 2024
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
6 KB (514 words) - 21:03, 25 November 2022
n-Myc MXD4 TCF4 Group C bHLH-PAS AhR AHRR ARNT ARNTL ARNTL2 CLOCK HIF 1A EPAS1 3A NPAS 1 2 3 PER 1 2 3 Period SIM 1 2 Group D BHLH 2 3 9 Pho4 ID 1 2 3...
19 KB (2,243 words) - 23:46, 9 September 2024