Epithelial cell adhesion molecule (redirect from EpCAM)
Epithelial cell adhesion molecule (EpCAM), also known as CD326 among other names, is a transmembrane glycoprotein mediating Ca2+-independent homotypic...
20 KB (2,451 words) - 18:22, 29 November 2024
EpCAM. It was developed by Fresenius Biotech and Trion Pharma (Germany). The drug is used for the treatment of malignant ascites in people with EpCAM-positive...
9 KB (814 words) - 05:50, 21 October 2024
DNA mutation in one of the MMR genes (MLH1, MSH2, MSH6, and PMS2) or the EPCAM gene, identified by genetic testing. Candidates for germline genetic testing...
48 KB (4,986 words) - 00:50, 22 November 2024
aid in the diagnosis of basal cell carcinoma (BCC). It is an antibody to EpCAM (epithelial cell adhesion molecule). BerEp4 has a high sensitivity and specificity...
3 KB (210 words) - 23:22, 15 December 2021
One of the scFvs binds to T cells via the CD3 receptor, and the other to EpCAM as a tumor antigen against gastrointestinal, lung, and other cancers. Like...
3 KB (256 words) - 16:20, 9 February 2023
use in the European Union in June 2022. Solitomab links T cells with the EpCAM antigen which is expressed by colon, gastric, prostate, ovarian, lung, and...
12 KB (1,710 words) - 23:52, 30 October 2024
levels of EpCAM-positive cells. Patients with severe skin burns can also carry EpCAM positive cells in the blood. Therefore, the use of EpCAM-positive...
68 KB (8,271 words) - 18:13, 8 November 2024
human dilated cardiomyopathy. CD326 Epithelial cell adhesion molecule (EpCAM) or Tumor-associated calcium signal transducer 1 (TACSTD1). Expressed on...
96 KB (492 words) - 06:06, 25 November 2024
(thyroid transcription factor-1) Podoplanin (PDPN) Claudin-4 Osteopontin Epithelial cell adhesion molecule (EpCAM) Estrogen receptor alpha Mammaglobin...
94 KB (10,649 words) - 07:10, 30 December 2024
transmembrane receptor of ligands Dickkopf1, Dickkopf2, Dickkopf3, Dickkopf4, EpCAM and Rspondin1. This gene encodes a high-affinity dickkopf homolog 1 (DKK1)...
6 KB (774 words) - 11:53, 15 November 2024
molecule (EpCAM) on chromosome 2 (2p21) and SPINT2 on chromosome 19. SPINT2 is a Kunitz-type protease inhibitor. The mutation in the EpCAM gene in Kuwait...
7 KB (758 words) - 18:54, 3 December 2023
idiopathic arthritis, hemolytic disease of the newborn Adecatumumab mab human EpCAM prostate and breast cancer Aducanumab Aduhelm mab human Amyloid beta Y Alzheimer's...
138 KB (4,154 words) - 05:18, 17 December 2024
of the four DNA mismatch repair genes (MLH1, MSH2, MSH6, PMS2), or the EpCAM gene. The relative risks of men vs. women with these inherited syndromes...
37 KB (4,659 words) - 08:03, 28 November 2024
interacts with E-cadherin and actin, as well as the cell adhesion molecule EpCam in the EVL, which may modulate adhesion with the underlying deep cells....
14 KB (1,710 words) - 12:42, 11 July 2024
a monoclonal antibody which binds to epithelial cell adhesion molecule (EpCAM, the tumor-associated calcium signal transducer 1). Oportuzumab is fused...
3 KB (225 words) - 23:43, 17 July 2024
target tumor cells. It binds to the epithelial cell adhesion molecule (EpCAM - CD326), with the intent to trigger antibody-dependent cellular cytotoxicity...
3 KB (243 words) - 21:09, 15 March 2024
mouse-derived monoclonal antibody targeting the cell-surface glycoprotein EpCAM (17-1A), which is expressed on epithelial tissues and on various carcinomas...
4 KB (273 words) - 20:33, 1 December 2023
emtansine Trastuzumab deruxtecan Zanidatamab ) Others for solid tumors EpCAM (Catumaxomab Edrecolomab) VEGF-A (Bevacizumab) Leukemia/lymphoma lymphoid:...
12 KB (821 words) - 06:14, 23 December 2024
characterized by negative expression of CD45 and positive expression of EpCAM. Then TECs are divided into two phenotypically and functionally different...
12 KB (1,416 words) - 21:10, 22 December 2024
biopsy analysis. Beads conjugate to anti‐epithelial cell adhesion molecule (EpCAM) antibodies for positive selection in the CTCs isolation chip (iCHIP). CTCs...
104 KB (11,627 words) - 07:57, 3 December 2024
known oncogene, epithelial cell adhesion molecule (EpCAM). Here, expression of BC200 RNA and EpCAM are believed to be correlated as they both play a role...
20 KB (2,531 words) - 23:18, 28 August 2023
antibodies approved for therapeutic use, binds both CD3 on cytotoxic T cells and EpCAM on human adenocarcinomas. The Fc region additionally binds to a cell that...
31 KB (3,539 words) - 06:15, 5 December 2024
VAR2CSA malaria protein efficiently retrieves circulating tumor cells in an EpCAM-independent manner". Nature Communications. 9 (1): 3279. Bibcode:2018NatCo...
25 KB (2,241 words) - 22:12, 8 December 2024
HGNC:3381 P16452 4994 EPC1 HGNC:19876 Q9H2F5 4995 EPC2 HGNC:24543 Q52LR7 4996 EPCAM HGNC:11529 P16422 4997 EPCIP HGNC:1305 Q9NYP8 4998 EPDR1 HGNC:17572 Q9UM22...
277 KB (17 words) - 18:34, 6 October 2024
the cell adhesion, for example Cldn 7 binds directly to adhesion molecule EpCAM on the cell membrane. And Cldn 16 is associated with reabsorption of divalent...
14 KB (1,909 words) - 14:43, 15 May 2024
American biologist, focusing in epidermal Langerhans cells, dendritic cells, EpCAM (epithelial cell adhesion molecule), distal-less and skin immunology, currently...
2 KB (108 words) - 04:46, 11 February 2023
Tumor-associated calcium signal transducer 1 (Epithelial cell adhesion molecule, EpCAM) Tumor-associated calcium signal transducer 2 This disambiguation page lists...
289 bytes (71 words) - 18:25, 17 November 2009
by bispecific oncolytic measles viruses simultaneously using HER2/neu or EpCAM as target receptors. Hanauer JR, Gottschlich L, Riehl D, Rusch T, Koch V...
8 KB (1,073 words) - 20:51, 10 November 2024
"LINC00152 promotes proliferation in hepatocellular carcinoma by targeting EpCAM via the mTOR signaling pathway". Oncotarget. 6 (40): 42813–24. doi:10.18632/oncotarget...
4 KB (583 words) - 22:38, 3 May 2024
emtansine Trastuzumab deruxtecan Zanidatamab ) Others for solid tumors EpCAM (Catumaxomab Edrecolomab) VEGF-A (Bevacizumab) Leukemia/lymphoma lymphoid:...
12 KB (758 words) - 23:46, 14 March 2024