• Thumbnail for Elevated alkaline phosphatase
    Elevated alkaline phosphatase occurs when levels of alkaline phosphatase (ALP) exceed the reference range. This group of enzymes has a low substrate specificity...
    15 KB (1,662 words) - 21:45, 20 June 2024
  • Thumbnail for Alkaline phosphatase
    The enzyme alkaline phosphatase (ALP, alkaline phenyl phosphatase) is a phosphatase with the physiological role of dephosphorylating compounds. The enzyme...
    55 KB (6,147 words) - 03:33, 2 November 2024
  • depleted Elevated aspartate aminotransferase (AST), bilirubin and lactate dehydrogenase (LDH) Hypercalcemia and elevated alkaline phosphatase due to increased...
    29 KB (2,927 words) - 21:22, 1 June 2024
  • Thumbnail for Ulcerative colitis
    (cholestatic pattern). This is often displayed by markedly elevated alkaline phosphatase levels and milder or no elevation in liver enzyme levels. Results...
    142 KB (16,206 words) - 01:32, 14 November 2024
  • Thumbnail for Paget's disease of bone
    first clinical manifestation of Paget's disease is usually an elevated alkaline phosphatase in the blood. Paget's disease may be diagnosed using one or...
    41 KB (4,772 words) - 19:55, 23 August 2024
  • Thumbnail for Hyperphosphatasia with mental retardation syndrome
    characterized by severe mental retardation, considerably elevated serum levels of alkaline phosphatase, hypoplastic terminal phalanges, and distinct facial...
    7 KB (595 words) - 18:17, 30 October 2024
  • Thumbnail for Sarcoma
    may be associated with elevated alkaline phosphatase levels, while others (such as Ewing sarcoma) can be associated with elevated erythrocyte sedimentation...
    37 KB (4,087 words) - 06:31, 11 October 2024
  • Thumbnail for ALPL
    Alkaline phosphatase, tissue-nonspecific isozyme is an enzyme that in humans is encoded by the ALPL gene. There are at least four distinct but related...
    17 KB (2,063 words) - 04:51, 6 September 2024
  • Thumbnail for Feathery degeneration
    obesity); it also has cytoplasmic clearing and cell swelling. Elevated alkaline phosphatase (ALP) Mallory body Non-alcoholic fatty liver disease Steatohepatitis...
    2 KB (132 words) - 21:12, 29 July 2023
  • Thumbnail for Cysteamine
    depression, and encephalopathy, low white blood cell levels, elevated alkaline phosphatase, and idiopathic intracranial hypertension that can cause headache...
    21 KB (1,618 words) - 01:40, 12 November 2024
  • conditions linked to the biliary tract (gamma-glutamyl transferase and alkaline phosphatase). Because some of these tests do not measure function, it is more...
    24 KB (2,897 words) - 05:51, 21 July 2024
  • Thumbnail for Alanine transaminase
    For example, elevated ALT levels due to hepatocyte damage can be distinguished from bile duct problems by measuring alkaline phosphatase. Also, myopathy-related...
    13 KB (1,370 words) - 19:23, 21 September 2024
  • A protein phosphatase is a phosphatase enzyme that removes a phosphate group from the phosphorylated amino acid residue of its substrate protein. Protein...
    21 KB (2,519 words) - 14:43, 22 June 2024
  • Thumbnail for X-linked hypophosphatemia
    is shown to target the major symptoms of XLH by decreasing elevated alkaline phosphatase and normalizing severe hypophosphatemia, leading to substantial...
    28 KB (2,782 words) - 21:35, 21 November 2024
  • Malabsorption Fat-soluble vitamin deficiencies Elevated alkaline phosphatase Elevated gamma-glutamyltransferase Elevated conjugated bilirubin In fetal and neonatal...
    3 KB (271 words) - 21:38, 2 November 2024
  • universally elevated. Alkaline phosphatase is often elevated in pregnancy due to production from the placenta, but may be additionally elevated. Other abnormalities...
    17 KB (1,954 words) - 12:21, 20 October 2024
  • product of the breast cancer-associated MUC1 gene. Elevated CA15-3, in conjunction with alkaline phosphatase (ALP), was found to be associated with an increased...
    2 KB (275 words) - 19:38, 30 June 2024
  • Thumbnail for Moclobemide
    250 mg/kg only a slight loss of weight, and with 250 mg/kg mildly elevated Alkaline phosphatase and Gamma-GT. Studies in dogs revealed no toxicity relevant...
    83 KB (9,142 words) - 14:24, 11 November 2024
  • Thumbnail for Hypophosphatasia
    Hypophosphatasia (/ˌhaɪpoʊˈfɒsfeɪtˌeɪʒə/; also called deficiency of alkaline phosphatase, phosphoethanolaminuria, or Rathbun's syndrome; sometimes abbreviated...
    41 KB (4,499 words) - 13:02, 2 September 2024
  • forms typically seen in acute leukemia. Serum leukocyte alkaline phosphatase is normal or elevated in leukemoid reaction, but is depressed in chronic myelogenous...
    5 KB (469 words) - 21:40, 19 October 2024
  • Thumbnail for Cholestasis
    titer of anti-mitochondrial antibody (AMA) against PDC-E2 and elevated alkaline phosphatase persisting for 6+ months. Ursodeoxycholic acid (UDCA) is an...
    112 KB (12,705 words) - 05:14, 2 November 2024
  • Thumbnail for Retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations
    All patients with RVCL develop kidney and liver disease, with elevated alkaline phosphatase. Some patients develop bone lesions (osteonecrosis) as well...
    17 KB (1,801 words) - 06:00, 24 June 2024
  • Thumbnail for ALPPL2
    Alkaline phosphatase, placental-like 2 is a protein that in humans is encoded by the ALPPL2 gene. There are at least four distinct but related alkaline...
    4 KB (582 words) - 21:07, 11 October 2022
  • Thumbnail for Dimethyl phthalate
    established hepatotoxic effects including increased liver weight, elevated alkaline phosphatase activity and reduced cholesterol and lipid levels. Increased...
    24 KB (2,515 words) - 05:55, 22 November 2024
  • nilutamide, and bicalutamide), there has been no evidence of hepatotoxicity or elevated liver enzymes in association with enzalutamide treatment in clinical trials...
    85 KB (8,727 words) - 01:24, 2 September 2024
  • Thumbnail for Osteomalacia
    of renal osteodystrophy Elevated serum alkaline phosphatase (due to an increase in compensatory osteoblast activity) Elevated parathyroid hormone (due...
    16 KB (1,666 words) - 16:03, 20 November 2024
  • Thumbnail for 5'-nucleotidase
    liver problems. The combined assays of serum 5'nucleotisase and alkaline phosphatase (AP) activities are extremely helpful in differential diagnosis since...
    15 KB (1,598 words) - 21:11, 19 February 2024
  • Thumbnail for Reynolds syndrome
    anemia. Typical clinical features include jaundice, elevated blood levels of alkaline phosphatase, calcinosis cutis, telangiectasias, and pruritus. This...
    3 KB (193 words) - 02:53, 13 January 2024
  • Biochemical studies reveal hypophosphatemia (low blood phosphate), elevated alkaline phosphatase and low serum 1,25 dihydroxyvitamin D levels. Routine laboratory...
    11 KB (1,162 words) - 13:44, 26 July 2024
  • Thumbnail for Hyperparathyroidism
    serum phosphate levels are generally elevated because of kidney disease.[citation needed] Alkaline phosphatase levels are usually high in hyperparathyroidism...
    53 KB (5,241 words) - 03:36, 19 October 2024