Elevated alkaline phosphatase occurs when levels of alkaline phosphatase (ALP) exceed the reference range. This group of enzymes has a low substrate specificity...
15 KB (1,662 words) - 21:45, 20 June 2024
The enzyme alkaline phosphatase (ALP, alkaline phenyl phosphatase) is a phosphatase with the physiological role of dephosphorylating compounds. The enzyme...
55 KB (6,147 words) - 03:33, 2 November 2024
depleted Elevated aspartate aminotransferase (AST), bilirubin and lactate dehydrogenase (LDH) Hypercalcemia and elevated alkaline phosphatase due to increased...
29 KB (2,927 words) - 21:22, 1 June 2024
(cholestatic pattern). This is often displayed by markedly elevated alkaline phosphatase levels and milder or no elevation in liver enzyme levels. Results...
142 KB (16,206 words) - 01:32, 14 November 2024
first clinical manifestation of Paget's disease is usually an elevated alkaline phosphatase in the blood. Paget's disease may be diagnosed using one or...
41 KB (4,772 words) - 19:55, 23 August 2024
characterized by severe mental retardation, considerably elevated serum levels of alkaline phosphatase, hypoplastic terminal phalanges, and distinct facial...
7 KB (595 words) - 18:17, 30 October 2024
may be associated with elevated alkaline phosphatase levels, while others (such as Ewing sarcoma) can be associated with elevated erythrocyte sedimentation...
37 KB (4,087 words) - 06:31, 11 October 2024
ALPL (redirect from Tissue-nonspecific alkaline phosphatase)
Alkaline phosphatase, tissue-nonspecific isozyme is an enzyme that in humans is encoded by the ALPL gene. There are at least four distinct but related...
17 KB (2,063 words) - 04:51, 6 September 2024
obesity); it also has cytoplasmic clearing and cell swelling. Elevated alkaline phosphatase (ALP) Mallory body Non-alcoholic fatty liver disease Steatohepatitis...
2 KB (132 words) - 21:12, 29 July 2023
depression, and encephalopathy, low white blood cell levels, elevated alkaline phosphatase, and idiopathic intracranial hypertension that can cause headache...
21 KB (1,618 words) - 01:40, 12 November 2024
conditions linked to the biliary tract (gamma-glutamyl transferase and alkaline phosphatase). Because some of these tests do not measure function, it is more...
24 KB (2,897 words) - 05:51, 21 July 2024
Alanine transaminase (redirect from Elevated ALT)
For example, elevated ALT levels due to hepatocyte damage can be distinguished from bile duct problems by measuring alkaline phosphatase. Also, myopathy-related...
13 KB (1,370 words) - 19:23, 21 September 2024
A protein phosphatase is a phosphatase enzyme that removes a phosphate group from the phosphorylated amino acid residue of its substrate protein. Protein...
21 KB (2,519 words) - 14:43, 22 June 2024
is shown to target the major symptoms of XLH by decreasing elevated alkaline phosphatase and normalizing severe hypophosphatemia, leading to substantial...
28 KB (2,782 words) - 21:35, 21 November 2024
Malabsorption Fat-soluble vitamin deficiencies Elevated alkaline phosphatase Elevated gamma-glutamyltransferase Elevated conjugated bilirubin In fetal and neonatal...
3 KB (271 words) - 21:38, 2 November 2024
universally elevated. Alkaline phosphatase is often elevated in pregnancy due to production from the placenta, but may be additionally elevated. Other abnormalities...
17 KB (1,954 words) - 12:21, 20 October 2024
product of the breast cancer-associated MUC1 gene. Elevated CA15-3, in conjunction with alkaline phosphatase (ALP), was found to be associated with an increased...
2 KB (275 words) - 19:38, 30 June 2024
250 mg/kg only a slight loss of weight, and with 250 mg/kg mildly elevated Alkaline phosphatase and Gamma-GT. Studies in dogs revealed no toxicity relevant...
83 KB (9,142 words) - 14:24, 11 November 2024
Hypophosphatasia (/ˌhaɪpoʊˈfɒsfeɪtˌeɪʒə/; also called deficiency of alkaline phosphatase, phosphoethanolaminuria, or Rathbun's syndrome; sometimes abbreviated...
41 KB (4,499 words) - 13:02, 2 September 2024
forms typically seen in acute leukemia. Serum leukocyte alkaline phosphatase is normal or elevated in leukemoid reaction, but is depressed in chronic myelogenous...
5 KB (469 words) - 21:40, 19 October 2024
titer of anti-mitochondrial antibody (AMA) against PDC-E2 and elevated alkaline phosphatase persisting for 6+ months. Ursodeoxycholic acid (UDCA) is an...
112 KB (12,705 words) - 05:14, 2 November 2024
All patients with RVCL develop kidney and liver disease, with elevated alkaline phosphatase. Some patients develop bone lesions (osteonecrosis) as well...
17 KB (1,801 words) - 06:00, 24 June 2024
Alkaline phosphatase, placental-like 2 is a protein that in humans is encoded by the ALPPL2 gene. There are at least four distinct but related alkaline...
4 KB (582 words) - 21:07, 11 October 2022
established hepatotoxic effects including increased liver weight, elevated alkaline phosphatase activity and reduced cholesterol and lipid levels. Increased...
24 KB (2,515 words) - 05:55, 22 November 2024
nilutamide, and bicalutamide), there has been no evidence of hepatotoxicity or elevated liver enzymes in association with enzalutamide treatment in clinical trials...
85 KB (8,727 words) - 01:24, 2 September 2024
of renal osteodystrophy Elevated serum alkaline phosphatase (due to an increase in compensatory osteoblast activity) Elevated parathyroid hormone (due...
16 KB (1,666 words) - 16:03, 20 November 2024
5'-nucleotidase (redirect from 5'-adenylic phosphatase)
liver problems. The combined assays of serum 5'nucleotisase and alkaline phosphatase (AP) activities are extremely helpful in differential diagnosis since...
15 KB (1,598 words) - 21:11, 19 February 2024
anemia. Typical clinical features include jaundice, elevated blood levels of alkaline phosphatase, calcinosis cutis, telangiectasias, and pruritus. This...
3 KB (193 words) - 02:53, 13 January 2024
Biochemical studies reveal hypophosphatemia (low blood phosphate), elevated alkaline phosphatase and low serum 1,25 dihydroxyvitamin D levels. Routine laboratory...
11 KB (1,162 words) - 13:44, 26 July 2024
Hyperparathyroidism (section Alkaline phosphatase)
serum phosphate levels are generally elevated because of kidney disease.[citation needed] Alkaline phosphatase levels are usually high in hyperparathyroidism...
53 KB (5,241 words) - 03:36, 19 October 2024